Isabel Pareés
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View article: Evaluation of Free-Living Motor Symptoms in Patients With Parkinson Disease Through Smartwatches: Protocol for Defining Digital Biomarkers
Evaluation of Free-Living Motor Symptoms in Patients With Parkinson Disease Through Smartwatches: Protocol for Defining Digital Biomarkers Open
Background Monitoring motor symptoms in patients with Parkinson disease (PD) presents significant challenges due to the complex nature of symptom progression, variations in medication responses, and the fluctuations that can occur througho…
View article: Correction: Heterogeneity of cognitive progression and clinical predictors in Parkinson’s disease–subjective cognitive decline
Correction: Heterogeneity of cognitive progression and clinical predictors in Parkinson’s disease–subjective cognitive decline Open
View article: Heterogeneity of cognitive progression and clinical predictors in Parkinson’s disease–subjective cognitive decline
Heterogeneity of cognitive progression and clinical predictors in Parkinson’s disease–subjective cognitive decline Open
View article: Evaluation of Free-Living Motor Symptoms in Patients With Parkinson Disease Through Smartwatches: Protocol for Defining Digital Biomarkers (Preprint)
Evaluation of Free-Living Motor Symptoms in Patients With Parkinson Disease Through Smartwatches: Protocol for Defining Digital Biomarkers (Preprint) Open
BACKGROUND Monitoring motor symptoms in patients with Parkinson disease (PD) presents significant challenges due to the complex nature of symptom progression, variations in medication responses, and the fluctuations that can occur through…
View article: Dysphagia in Parkinson´s disease. A 5-year follow-up study
Dysphagia in Parkinson´s disease. A 5-year follow-up study Open
Background and objective Dysphagia at time of diagnosis suggests atypical parkinsonism instead Parkinson´s disease (PD). Our aim was to analyze the frequency of dysphagia in patients with early PD comparing with a control group and to iden…
View article: 20604. LA CLASIFICACIÓN MNCD CORRELACIONA MEJOR CON LA CALIDAD DE VIDA Y SITUACIÓN FUNCIONAL EN LOS PACIENTES CON ENFERMEDAD DE PARKINSON QUE EL HOEHN Y YAHR
20604. LA CLASIFICACIÓN MNCD CORRELACIONA MEJOR CON LA CALIDAD DE VIDA Y SITUACIÓN FUNCIONAL EN LOS PACIENTES CON ENFERMEDAD DE PARKINSON QUE EL HOEHN Y YAHR Open
View article: Functional neurological disorder in Europe: regional differences in education and health policy
Functional neurological disorder in Europe: regional differences in education and health policy Open
Background Functional neurological disorder (FND) is a common cause of neurological disability. Despite recent advances in pathophysiological understanding and treatments, application of this knowledge to clinical practice is variable and …
View article: Beyond movement: Headache in patients with functional movement disorders
Beyond movement: Headache in patients with functional movement disorders Open
Objective To evaluate headache comorbidity in a cohort of patients with functional movement disorders by assessing the prevalence, clinical characteristics, and temporal relationship of headache with the onset of functional symptoms. Backg…
View article: Influence of the Level of Education on the Change in Cognitive Function in Parkinson´s Disease. A 5-year Follow-up Study.
Influence of the Level of Education on the Change in Cognitive Function in Parkinson´s Disease. A 5-year Follow-up Study. Open
Background and objective: Level of Education (LoE) is widely used as an indicator of cognitive reserve and is associated with risk of dementia. The aim of the present study was to know the influence of the LoE on the change in cognitive fu…
View article: Concomitant treatment with safinamide and antidepressant drugs: Safety data from real clinical practice
Concomitant treatment with safinamide and antidepressant drugs: Safety data from real clinical practice Open
Our real clinical practice study suggests that concomitant use of safinamide with antidepressant drugs in PD patients seemed to be safe and well tolerated, even in the long term. However, caution is warranted, individualizing treatment reg…
View article: Functional comorbidity in Parkinson disease: A window of opportunity
Functional comorbidity in Parkinson disease: A window of opportunity Open
View article: Functional neurological disorder is a feminist issue
Functional neurological disorder is a feminist issue Open
Functional neurological disorder (FND) is a common and disabling disorder, often misunderstood by clinicians. Although viewed sceptically by some, FND is a diagnosis that can be made accurately, based on positive clinical signs, with clini…
View article: Validation of the <scp>OPTIMIPARK</scp> Questionnaire: A Tool to Optimize Treatment in Parkinson's Disease
Validation of the <span>OPTIMIPARK</span> Questionnaire: A Tool to Optimize Treatment in Parkinson's Disease Open
Background Dopamine replacement therapy reduces most motor and nonmotor features of Parkinson's disease. However, with disease progression, adjustments of dopaminergics and the application of advanced therapies must be considered. Objectiv…
View article: Teaching Video NeuroImage: Hung-Up Reflex in Stiff Limb Syndrome
Teaching Video NeuroImage: Hung-Up Reflex in Stiff Limb Syndrome Open
A 45-year-old woman developed an intermittent gait disorder and agoraphobia that was initially diagnosed as a functional movement disorder (FMD). Examination revealed fluctuating left leg stiffness with a hung-up reflex (Video 1). Neuroima…
View article: A Critical Investigation of Cerebellar Associative Learning in Isolated Dystonia
A Critical Investigation of Cerebellar Associative Learning in Isolated Dystonia Open
Background Impaired eyeblink conditioning is often cited as evidence for cerebellar dysfunction in isolated dystonia yet the results from individual studies are conflicting and underpowered. Objective To systematically examine the influenc…
View article: Gamma Knife® stereotactic radiosurgery as a treatment for essential and parkinsonian tremor: long-term experience
Gamma Knife® stereotactic radiosurgery as a treatment for essential and parkinsonian tremor: long-term experience Open
This is the largest series of patients with essential and parkinsonian tremor treated with GKT and followed up in the long term in Spain. GKT can be safe and effective in the long term in patients with refractory tremor, including in elder…
View article: Concomitant treatment with safinamide and antidepressant drugs: Safety data from real clinical practice
Concomitant treatment with safinamide and antidepressant drugs: Safety data from real clinical practice Open
Our real clinical practice study suggests that concomitant use of safinamide with antidepressant drugs in PD patients seemed to be safe and well tolerated, even in the long term. However, caution is warranted, individualizing treatment reg…
View article: The final blink: intact eyeblink conditioning in isolated dystonia
The final blink: intact eyeblink conditioning in isolated dystonia Open
Structured Abstract Background Impaired eyeblink conditioning is often cited as evidence for cerebellar dysfunction in isolated dystonia yet the results from individual studies are conflicting and underpowered. Objective To systematically …
View article: Impulse Control Disorders in Parkinson's Disease: Has <scp>COVID‐19</scp> Related Lockdown Been a Trigger?
Impulse Control Disorders in Parkinson's Disease: Has <span>COVID‐19</span> Related Lockdown Been a Trigger? Open
Background Parkinson's disease (PD) patients, especially those on dopamine agonists (DA), are at risk of impulse control disorders (ICD). Little attention has been paid to the influence of environmental factors. Cases Retrospective analysi…
View article: Dystonia in a Female Fragile X Premutation Carrier
Dystonia in a Female Fragile X Premutation Carrier Open
Fragile X-associated tremor ataxia syndrome (FXTAS) is the most common neurological manifestation described in carriers of a premutation expansion (55–200 CGG repeats) of the fragile X mental retardation 1 (FMR1) gene.1 FXTAS affects mainl…
View article: Patients' Perspective of Dystonia Symptoms during the SARS‐CoV‐2 Pandemic
Patients' Perspective of Dystonia Symptoms during the SARS‐CoV‐2 Pandemic Open
View article: Evidence for a Window of Enhanced Plasticity in the Human Motor Cortex Following Ischemic Stroke
Evidence for a Window of Enhanced Plasticity in the Human Motor Cortex Following Ischemic Stroke Open
Background In preclinical models, behavioral training early after stroke produces larger gains compared with delayed training. The effects are thought to be mediated by increased and widespread reorganization of synaptic connections in the…
View article: Management of Parkinson’s disease and other movement disorders in women of childbearing age: Part 1
Management of Parkinson’s disease and other movement disorders in women of childbearing age: Part 1 Open
View article: Management of Parkinson’s disease and other movement disorders in women of childbearing age: Part 2
Management of Parkinson’s disease and other movement disorders in women of childbearing age: Part 2 Open
Introduction: Many diseases associated with hyperkinetic movement disorders manifest in women of childbearing age. It is important to understand the risks of these diseases during pregnancy, and the potential risks of treatment for the fet…
View article: COVID-19 in Parkinson’s disease: what holds the key?
COVID-19 in Parkinson’s disease: what holds the key? Open
View article: Non-motor symptom burden in patients with Parkinson’s disease with impulse control disorders and compulsive behaviours: results from the COPPADIS cohort
Non-motor symptom burden in patients with Parkinson’s disease with impulse control disorders and compulsive behaviours: results from the COPPADIS cohort Open
View article: Manejo de la enfermedad de Parkinson y otros trastornos del movimiento en mujeres en edad fértil: parte 2
Manejo de la enfermedad de Parkinson y otros trastornos del movimiento en mujeres en edad fértil: parte 2 Open
View article: Radiocirugía estereotáctica con Gamma Knife® como tratamiento del temblor esencial y parkinsoniano: experiencia a largo plazo
Radiocirugía estereotáctica con Gamma Knife® como tratamiento del temblor esencial y parkinsoniano: experiencia a largo plazo Open
This is the largest series of patients with essential and parkinsonian tremor treated with GKT and followed up in the long term in Spain. GKT can be safe and effective in the long term in patients with refractory tremor, including in elder…
View article: Impact of the Coronavirus Disease 2019 Pandemic on Functional Movement Disorders: Lessons From a Specialized Clinic
Impact of the Coronavirus Disease 2019 Pandemic on Functional Movement Disorders: Lessons From a Specialized Clinic Open
The coronavirus disease 2019 (COVID-19) crisis has had a major impact on healthcare systems and patients with movement disorders.1 Functional movement disorders (FMDs) may affect up to 18% of patients evaluated in movement disorder units a…
View article: Manejo de la enfermedad de Parkinson y otros trastornos del movimiento en mujeres en edad fértil: Parte 1
Manejo de la enfermedad de Parkinson y otros trastornos del movimiento en mujeres en edad fértil: Parte 1 Open