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View article: Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy Open
Viral peptide is key to T cell priming Simian immunodeficiency virus (SIV) vaccines containing a strain 68-1 rhesus cytomegalovirus (RhCMV) vector elicit strong CD8 + T cell responses that can control and clear SIV infections. The SIV pept…
View article: Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy Open
Strain 68-1 rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens elicit CD8 + T cells that recognize peptide epitopes presented by major histocompatibility complex (MHC)-II and MHC-E molecules, ins…
View article: Examination of Vesicular Stomatitis Virus-Induced Morphology Changes in Individual Vero Cells By Qmod Microscopy
Examination of Vesicular Stomatitis Virus-Induced Morphology Changes in Individual Vero Cells By Qmod Microscopy Open
Viral infection of cultured cells induces changes in the biophysical characteristics of the affected cells. Advanced microscopic cameras such as Ovizio's QMod, coupled with the appropriate software, can measure a variety of characteristics…
View article: Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge
Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge Open
The development of a sterilizing vaccine against malaria remains one of the highest priorities for global health research. While sporozoite vaccines targeting the pre-erythrocytic stage show great promise, it has not been possible to maint…