Isabella V. Trachtenberg
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View article: Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress
Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress Open
Uveal melanoma (UM) is the deadliest form of eye cancer in adults. Inactivating mutations and/or loss of expression of the gene encoding BRCA1-associated protein 1 (BAP1) in UM tumors are associated with an increased risk of metastasis. To…
View article: Supplementary Figure 2 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 2 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
SOX10/Sox10-knockout does not alter sensitivity to cell death mediated by other cytokines
View article: Supplementary Figure 4 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 4 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
SOX10-knockout does not consistently alter cytokine receptor expression
View article: Supplementary Figure 3 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 3 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
SOX10-knockout does not strongly affect the expression of cytokine signaling mediators
View article: Data from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Data from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
The transcription factor, SOX10, plays an important role in the differentiation of neural crest precursors to the melanocytic lineage. Malignant transformation of melanocytes leads to the development of melanoma, and SOX10 promotes melanom…
View article: Supplementary Figure 6 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 6 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
RIPK1 is not activated in response to TNFα treatment
View article: Supplementary Figure 7 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 7 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Caspase-dependent GSDME cleavage is observed concomitant with cytokine-mediated cell death
View article: Supplementary Table 1 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Table 1 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
RPPA Data
View article: Uncropped Blots from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Uncropped Blots from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Uncropped Western blots.
View article: Supplementary Figure 7 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 7 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Caspase-dependent GSDME cleavage is observed concomitant with cytokine-mediated cell death
View article: Supplementary Figure 8 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 8 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Other cytokines have less effect on GSDME cleavage in SOX10/Sox10-knockout cells
View article: Supplementary Figure 1 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 1 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
SOX10/Sox10-knockout cells are more sensitive to cytotoxic T cell-secreted cytokines
View article: Supplementary Figure 2 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 2 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
SOX10/Sox10-knockout does not alter sensitivity to cell death mediated by other cytokines
View article: Supplementary Table 1 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Table 1 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
RPPA Data
View article: Uncropped Blots from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Uncropped Blots from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Uncropped Western blots.
View article: Supplementary Figure 6 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 6 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
RIPK1 is not activated in response to TNFα treatment
View article: Supplementary Figure 3 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 3 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
SOX10-knockout does not strongly affect the expression of cytokine signaling mediators
View article: Supplementary Figure 1 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 1 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
SOX10/Sox10-knockout cells are more sensitive to cytotoxic T cell-secreted cytokines
View article: Data from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Data from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
The transcription factor, SOX10, plays an important role in the differentiation of neural crest precursors to the melanocytic lineage. Malignant transformation of melanocytes leads to the development of melanoma, and SOX10 promotes melanom…
View article: Supplementary Figure 5 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 5 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Cytokine treatment leads to caspase cleavage in SOX10-knockout cells
View article: Supplementary Materials and Methods from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Materials and Methods from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Materials and Methods for Supplementary Figures
View article: Supplementary Figure 5 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 5 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Cytokine treatment leads to caspase cleavage in SOX10-knockout cells
View article: Supplementary Figure 4 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 4 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
SOX10-knockout does not consistently alter cytokine receptor expression
View article: Supplementary Materials and Methods from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Materials and Methods from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Materials and Methods for Supplementary Figures
View article: Supplementary Figure 8 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
Supplementary Figure 8 from SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
Other cytokines have less effect on GSDME cleavage in SOX10/Sox10-knockout cells
View article: SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death
SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death Open
The transcription factor, SOX10, plays an important role in the differentiation of neural crest precursors to the melanocytic lineage. Malignant transformation of melanocytes leads to the development of melanoma, and SOX10 promotes melanom…