Isabelle Giraud
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View article: Identification of a sex-determining locus potentially involved in a conflict over sex-ratio
Identification of a sex-determining locus potentially involved in a conflict over sex-ratio Open
Sex-determining genes remain largely uncharacterized outside classical models in vertebrates and insects, leaving a gap in our understanding of their evolutionary emergence and sex chromosome formation. Terrestrial isopods, particularly th…
View article: Temporal stability of sex ratio distorter prevalence in natural populations of the isopod<i>Armadillidium vulgare</i>
Temporal stability of sex ratio distorter prevalence in natural populations of the isopod<i>Armadillidium vulgare</i> Open
In the terrestrial isopod Armadillidium vulgare , many females produce progenies with female-biased sex ratios due to two feminizing sex ratio distorters (SRD): Wolbachia endosymbionts and a nuclear non-mendelian locus called the f element…
View article: Involvement of Pharmacists in the Emergency Department to Correct Errors in the Medication History and the Impact on Adverse Drug Event Detection
Involvement of Pharmacists in the Emergency Department to Correct Errors in the Medication History and the Impact on Adverse Drug Event Detection Open
(1) Incomplete or wrong medication histories can lead to missed diagnoses of Adverse Drug Effects (ADEs). We aimed to evaluate pharmacist-identified ED errors in the medication histories obtained by physicians, and their consequences for A…
View article: Heterogeneous distribution of sex ratio distorters in natural populations of the isopod <i>Armadillidium vulgare</i>
Heterogeneous distribution of sex ratio distorters in natural populations of the isopod <i>Armadillidium vulgare</i> Open
In the isopod Armadillidium vulgare , many females produce progenies with female-biased sex ratios, owing to two feminizing sex ratio distorters (SRD): Wolbachia endosymbionts and the f element. We investigated the distribution and populat…
View article: Heterogeneous distribution of sex ratio distorters in natural populations of the isopod<i>Armadillidium vulgare</i>
Heterogeneous distribution of sex ratio distorters in natural populations of the isopod<i>Armadillidium vulgare</i> Open
In the isopod Armadillidium vulgare , many females produce progenies with female-biased sex ratios, due to two feminizing sex ratio distorters (SRD): Wolbachia endosymbionts and the f element. We investigated the distribution and populatio…
View article: Frequency, Characteristics, and Predictive Factors of Adverse Drug Events in an Adult Emergency Department according to Age: A Cross-Sectional Study
Frequency, Characteristics, and Predictive Factors of Adverse Drug Events in an Adult Emergency Department according to Age: A Cross-Sectional Study Open
Adverse drug events (ADEs) are a major public health concern, given their consequences in terms of morbi-mortality and associated healthcare costs. Many studies have focused on the elderly, who are considered particularly vulnerable in thi…
View article: Characterization of a Sex-Determining Region and Its Genomic Context via Statistical Estimates of Haplotype Frequencies in Daughters and Sons Sequenced in Pools
Characterization of a Sex-Determining Region and Its Genomic Context via Statistical Estimates of Haplotype Frequencies in Daughters and Sons Sequenced in Pools Open
Sex chromosomes are generally derived from a pair of autosomes that have acquired a locus controlling sex. Sex chromosomes may evolve reduced recombination around this locus and undergo a long process of molecular divergence. At that point…
View article: Impact of medication characteristics and adverse drug events on hospital admission after an emergency department visit: Prospective cohort study
Impact of medication characteristics and adverse drug events on hospital admission after an emergency department visit: Prospective cohort study Open
We identified variables associated with hospitalisation including drug-related variables. These results point out the importance and the relevance of collecting medication data in a subacute medical ED (study registered on ClinicalTrials.g…
View article: Draft Genome Sequences of Thelohania contejeani and Cucumispora dikerogammari, Pathogenic Microsporidia of Freshwater Crustaceans
Draft Genome Sequences of Thelohania contejeani and Cucumispora dikerogammari, Pathogenic Microsporidia of Freshwater Crustaceans Open
We announce the draft genome sequences of two pathogenic microsporidia of European freshwater crustaceans, Thelohania contejeani (the causative agent of porcelain disease) and Cucumispora dikerogammari . Both species are implicated in mass…
View article: Comparative Genomics of Strictly Vertically Transmitted, Feminizing Microsporidia Endosymbionts of Amphipod Crustaceans
Comparative Genomics of Strictly Vertically Transmitted, Feminizing Microsporidia Endosymbionts of Amphipod Crustaceans Open
Microsporidia are obligate intracellular eukaryotic parasites of vertebrates and invertebrates. Microsporidia are usually pathogenic and undergo horizontal transmission or a mix of horizontal and vertical transmission. However, cases of no…
View article: Characterization of a new case of XMLV (Bxv1) contamination in the human cell line Hep2 (clone 2B)
Characterization of a new case of XMLV (Bxv1) contamination in the human cell line Hep2 (clone 2B) Open
The use of misidentified cell lines contaminated by other cell lines and/or microorganisms has generated much confusion in the scientific literature. Detailed characterization of such contaminations is therefore crucial to avoid misinterpr…
View article: Characterization of a sex-determining region and its genomic context via statistical estimates of haplotype frequencies in daughters and sons sequenced in pools
Characterization of a sex-determining region and its genomic context via statistical estimates of haplotype frequencies in daughters and sons sequenced in pools Open
Sex chromosomes are generally derived from a pair of autosomes that have acquired a locus controlling sex. Sex chromosomes usually evolve reduced recombination around this locus and undergo a long process of molecular divergence. Although …
View article: Evolutionary transition to XY sex chromosomes associated with Y-linked duplication of a male hormone gene in a terrestrial isopod
Evolutionary transition to XY sex chromosomes associated with Y-linked duplication of a male hormone gene in a terrestrial isopod Open
Sex chromosomes are highly variable in some taxonomic groups, but the evolutionary mechanisms underlying this diversity are not well understood. In terrestrial isopod crustaceans, evolutionary turnovers in sex chromosomes are frequent, pos…
View article: Sex chromosomes control vertical transmission of feminizing Wolbachia symbionts in an isopod
Sex chromosomes control vertical transmission of feminizing Wolbachia symbionts in an isopod Open
Microbial endosymbiosis is widespread in animals, with major ecological and evolutionary implications. Successful symbiosis relies on efficient vertical transmission through host generations. However, when symbionts negatively affect host …
View article: Sex chromosomes control vertical transmission of feminizing <i>Wolbachia</i> symbionts in an isopod
Sex chromosomes control vertical transmission of feminizing <i>Wolbachia</i> symbionts in an isopod Open
Microbial endosymbiosis is widespread in animals, with major ecological and evolutionary implications. Successful symbiosis relies on efficient vertical transmission through host generations. However, when symbionts negatively affect host …
View article: The Genome of<i>Armadillidium vulgare</i>(Crustacea, Isopoda) Provides Insights into Sex Chromosome Evolution in the Context of Cytoplasmic Sex Determination
The Genome of<i>Armadillidium vulgare</i>(Crustacea, Isopoda) Provides Insights into Sex Chromosome Evolution in the Context of Cytoplasmic Sex Determination Open
The terrestrial isopod Armadillidium vulgare is an original model to study the evolution of sex determination and symbiosis in animals. Its sex can be determined by ZW sex chromosomes, or by feminizing Wolbachia bacterial endosymbionts. He…
View article: Investigating the Molecular Genetic Basis of Cytoplasmic Sex Determination Caused by Wolbachia Endosymbionts in Terrestrial Isopods
Investigating the Molecular Genetic Basis of Cytoplasmic Sex Determination Caused by Wolbachia Endosymbionts in Terrestrial Isopods Open
In animals, sexual differences between males and females are usually determined by sex chromosomes. Alternatively, sex may also be determined by vertically transmitted intracellular microbial endosymbionts. The best known cytoplasmic sex m…
View article: A Survey of Virus Recombination Uncovers Canonical Features of Artificial Chimeras Generated During Deep Sequencing Library Preparation
A Survey of Virus Recombination Uncovers Canonical Features of Artificial Chimeras Generated During Deep Sequencing Library Preparation Open
Chimeric reads can be generated by in vitro recombination during the preparation of high-throughput sequencing libraries. Our attempt to detect biological recombination between the genomes of dengue virus (DENV; +ssRNA genome) and its mosq…
View article: Pharmacist intervention to detect drug adverse events on admission to the emergency department: Two case reports of neuroleptic malignant syndrome
Pharmacist intervention to detect drug adverse events on admission to the emergency department: Two case reports of neuroleptic malignant syndrome Open
Adverse drug events may be severe and clinical pharmacists in emergency departments can help to detect them.
View article: Diversity and evolution of sex determination systems in terrestrial isopods
Diversity and evolution of sex determination systems in terrestrial isopods Open
Sex determination systems are highly variable in many taxa, sometimes even between closely related species. Yet the number and direction of transitions between these systems have seldom been characterized, and the underlying mechanisms are…
View article: Birth of a W sex chromosome by horizontal transfer of <i>Wolbachia</i> bacterial symbiont genome
Birth of a W sex chromosome by horizontal transfer of <i>Wolbachia</i> bacterial symbiont genome Open
Significance Sex determination is an evolutionarily ancient, key developmental pathway governing sexual differentiation in animals. Sex determination systems are remarkably variable between species or groups of species, however, and the ev…