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View article: Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects
Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects Open
View article: Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults
Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Plasmodium falciparum Sporozoite Vaccine in Tanzanian Adults Open
We are using controlled human malaria infection (CHMI) by direct venous inoculation (DVI) of cryopreserved, infectious Plasmodium falciparum (Pf) sporozoites (SPZ) (PfSPZ Challenge) to try to reduce time and costs of developing PfSPZ Vacci…
View article: A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein Open
View article: Immunization of Malaria-Preexposed Volunteers With PfSPZ Vaccine Elicits Long-Lived IgM Invasion-Inhibitory and Complement-Fixing Antibodies
Immunization of Malaria-Preexposed Volunteers With PfSPZ Vaccine Elicits Long-Lived IgM Invasion-Inhibitory and Complement-Fixing Antibodies Open
NCT02132299.
View article: Public antibodies to malaria antigens generated by two LAIR1 insertion modalities.
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities. Open
View article: Public antibodies to malaria antigens generated by two LAIR1 insertion modalities
Public antibodies to malaria antigens generated by two LAIR1 insertion modalities Open
View article: Functionally active serum and monoclonal antibody responses targeting the pre-erythrocytic stage of Plasmodium falciparum in Tanzanian adults after vaccination with purified, live-attenuated sporozoites
Functionally active serum and monoclonal antibody responses targeting the pre-erythrocytic stage of Plasmodium falciparum in Tanzanian adults after vaccination with purified, live-attenuated sporozoites Open
\nWith 212 million cases worldwide and an estimated 429,000 deaths in 2015, malaria continues to be a serious global health threat. An effective vaccine could significantly decrease malaria-associated morbidity and mortality, especially in…