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View article: Molecular <scp>IgE</scp> Reactivity Profiling With Micro‐Arrayed Allergens Reveals Distinct Interregional Patterns of Sensitization and a Hypoallergenic Region in Türkiye
Molecular <span>IgE</span> Reactivity Profiling With Micro‐Arrayed Allergens Reveals Distinct Interregional Patterns of Sensitization and a Hypoallergenic Region in Türkiye Open
Background Molecular immunoglobulin E ( IgE ) reactivity profiling with multiple micro‐arrayed allergens is a valuable tool in allergy diagnosis and has provided fundamental insights into the evolution of allergic sensitization in longitud…
View article: A practical and applicable desensitization scheme for ciprofloxacin with a glass of water
A practical and applicable desensitization scheme for ciprofloxacin with a glass of water Open
Desensitization is an immunological process that creates temporary tolerance to a drug, which disappears once treatment is discontinued. Ciprofloxacin is a commonly used antibiotic, particularly for chronic lung diseases, yet there are ver…
View article: A rare case of type IV hypersensitivity: Prilocaine allergy
A rare case of type IV hypersensitivity: Prilocaine allergy Open
Allergic reactions caused by local anesthetics are quite rare and these reactions often manifest as Type I (immediate-type) hypersensitivity; however, Type IV (delayed-type) hypersensitivity reactions also hold clinical significance. Type …
View article: Exploring the link between nutritional status and total antioxidant status in patients with severe asthma: a cross-sectional study
Exploring the link between nutritional status and total antioxidant status in patients with severe asthma: a cross-sectional study Open
Not applicable.
View article: What Does Radiologic Assessment Contribute to Asthma: A Subanalysis of the Turkish Adult Asthma Registry
What Does Radiologic Assessment Contribute to Asthma: A Subanalysis of the Turkish Adult Asthma Registry Open
Objectives It is aimed to assess how physicians use chest imaging in asthma and the relationship between the pathological findings and related disease characteristics in the radiological imaging of asthmatic patients. Background The daily …
View article: Old Questions, new answers: real-world long-term efficiency of hymenoptera venom immunotherapy
Old Questions, new answers: real-world long-term efficiency of hymenoptera venom immunotherapy Open
Background: Hymenoptera venom allergy is a potentially life-threatening allergic reaction. Venom immunotherapy (VIT) is recommended to prevent severe allergic reactions. Field stings indicate the effectiveness of immunotherapy.Objective: T…
View article: Socioeconomic status has direct impact on asthma control: Turkish adult asthma registry
Socioeconomic status has direct impact on asthma control: Turkish adult asthma registry Open
Background Asthma is one of the most common causes of chronic respiratory disease, and countries with low socioeconomic status have both a high prevalence of asthma and asthma‐related death. Objective In this study, we aimed to determine s…
View article: Trends in prescribing montelukast in patients with asthma in real-life: Results from the Turkish adult asthma registry
Trends in prescribing montelukast in patients with asthma in real-life: Results from the Turkish adult asthma registry Open
Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in asthma management remain limited. This registry-based study eval…
View article: Economic burden of short-acting beta-2 agonist (SABA) overuse among asthma patients in Türkiye: a cost analysis with respect to the updated GINA treatment recommendations
Economic burden of short-acting beta-2 agonist (SABA) overuse among asthma patients in Türkiye: a cost analysis with respect to the updated GINA treatment recommendations Open
Background This cost of illness study aimed to determine economic burden of short-acting β2-agonist (SABA) overuse in Türkiye from payer perspective with respect to the updated GINA 2022 treatment recommendations. Methods A total of 3,034,…
View article: Allergic Bronchopulmonary Aspergillosis Treated with Mepolizumab and Omalizumab: Switching Biological Agents
Allergic Bronchopulmonary Aspergillosis Treated with Mepolizumab and Omalizumab: Switching Biological Agents Open
Objective: Allergic bronchopulmonary aspergillosis (ABPA) is a fungal infection commonly seen in patients with uncontrolled severe asthma.Standard treatment includes glucocorticoids and itraconazole; however, the use of biological agents s…
View article: Effectiveness of mepolizumab in patients with severe eosinophilic asthma: In a real life study
Effectiveness of mepolizumab in patients with severe eosinophilic asthma: In a real life study Open
Although the number of patients in our study was limited, mepolizumab improved symptom scores in severe eosinophilic asthma, reduced the number of attacks, and improved pulmonary function test values.
View article: Drug hypersensitivity in drug-resistant tuberculosis
Drug hypersensitivity in drug-resistant tuberculosis Open
Our study is the first study in the literature that evaluated the drug hypersensitivity in drug resıstance tuberculosis patients. Drug hypersensitivity that develops with tuberculosis treatment may lead to discontinuation or change in trea…
View article: Picturing asthma in Turkey: results from the Turkish adult asthma registry
Picturing asthma in Turkey: results from the Turkish adult asthma registry Open
National data on asthma characteristics and the factors associated with uncontrolled asthma seem to be necessary for every country. For this purpose, we developed the Turkish Adult Asthma Registry for patients with asthma aiming to take a …
View article: Tuberculosis Treatment-related Lichenoid Drug Eruptions
Tuberculosis Treatment-related Lichenoid Drug Eruptions Open
Tuberculosis is one of the leading causes of death from infectious diseases in adults worldwide. Drug hypersensitivity in tuberculosis is an important problem affecting the treatment process. Although treatment is started with isoniazid, r…
View article: Treatment and Management of Hypersensitivity Reactions Developed Against Anti-Tuberculosis Drug
Treatment and Management of Hypersensitivity Reactions Developed Against Anti-Tuberculosis Drug Open
Background: The World Health Organization Global Tuberculosis Report 2021 defines tuberculosis as the second infectious disease that causes sickness and death after COVID 19 and ranks it as the 13 th among the global causes of death. Howev…
View article: The significance of eosinophil and eosinophil lymphocyte ratio (ELR) in predicting response to omalizumab treatment in patients with severe allergic asthma
The significance of eosinophil and eosinophil lymphocyte ratio (ELR) in predicting response to omalizumab treatment in patients with severe allergic asthma Open
Instead of expensive and invasive methods for predicting the response of omalizumab therapy in severe allergic asthma, the ELR is correlated with treatment response and giving hope to be easier way to reach.
View article: IGFBP-4: A promising biomarker for lung cancer
IGFBP-4: A promising biomarker for lung cancer Open
Background: Insulin-like growth factor binding protein-4 (IGFBP-4), a member of the insulin-like growth factor (IGF) family, transports, and regulates the activity of IGFs. The pregnancy-associated plasma protein-A (PAPP-A) has proteolytic…
View article: A patient with mushroom allergy; a new etiological agent of Kounis syndrome
A patient with mushroom allergy; a new etiological agent of Kounis syndrome Open
Kounis syndrome (KS) is a rarely diagnosed condition which should always be kept in mind when an acute myocardial infarction (AMI) happens in the context of anaphylactic reactions. We report a case of a 31-year old female; 2 hours after th…