Israel M. Barbash
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View article: Predictive factors for permanent pacemaker implantation and mortality after transcatheter aortic valve replacement in patients with pre-existing atrial fibrillation
Predictive factors for permanent pacemaker implantation and mortality after transcatheter aortic valve replacement in patients with pre-existing atrial fibrillation Open
Background: Atrial fibrillation (AF) is the most common arrhythmia among patients undergoing transcatheter aortic valve replacement (TAVR). Post-TAVR permanent pacemaker implantation (PPI) predictors for patients in sinus rhythm were studi…
View article: Estimating LVEF from ECG with GPT-4o Fine-Tuned Vision: A Novel Approach in AI-Driven Cardiac Diagnostics
Estimating LVEF from ECG with GPT-4o Fine-Tuned Vision: A Novel Approach in AI-Driven Cardiac Diagnostics Open
Background Assessing Left Ventricular Ejection Fraction (LVEF) is crucial for diagnosing reduced systolic function, yet echocardiography (ECHO) may not always be readily available, potentially delaying treatment. Electrocardiography (ECG) …
View article: Long-Term Clinical Outcomes of Left Atrial Appendage Closure in Patients with Left Atrial Appendage Thrombus
Long-Term Clinical Outcomes of Left Atrial Appendage Closure in Patients with Left Atrial Appendage Thrombus Open
Background: Patients with atrial fibrillation (AF) who have a high bleeding risk or contraindications to anticoagulation may be candidates for left atrial appendage closure (LAAC). However, the presence of a thrombus in the left atrial app…
View article: Randomized Controlled Trials Evaluating Artificial Intelligence in Cardiovascular Care
Randomized Controlled Trials Evaluating Artificial Intelligence in Cardiovascular Care Open
View article: Clinical significance and correlation of microRNA-21 expression in patients undergoing transcatheter aortic valve replacement
Clinical significance and correlation of microRNA-21 expression in patients undergoing transcatheter aortic valve replacement Open
A significant drop in circulating microRNA-21 levels 6 h after transcatheter aortic valve replacement (TAVR) was associated with a fourfold increased risk of major adverse cardiovascular or cerebrovascular events (MACCE). This prospective …
View article: Effectiveness of the GPT-4o Model in Interpreting Electrocardiogram Images for Cardiac Diagnostics: Diagnostic Accuracy Study
Effectiveness of the GPT-4o Model in Interpreting Electrocardiogram Images for Cardiac Diagnostics: Diagnostic Accuracy Study Open
Background Recent progress has demonstrated the potential of deep learning models in analyzing electrocardiogram (ECG) pathologies. However, this method is intricate, expensive to develop, and designed for specific purposes. Large language…
View article: European Society of Cardiology quality indicators for the management of acute coronary syndromes: developed in collaboration with the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the ESC
European Society of Cardiology quality indicators for the management of acute coronary syndromes: developed in collaboration with the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the ESC Open
Aims Closing the evidence-practice gap for the treatment of acute coronary syndrome (ACS) is central to improving quality of care. Under the European Society of Cardiology (ESC) framework, we aimed to develop updated quality indicators (QI…
View article: Temporal Trends in Patient Characteristics and Clinical Outcomes of TAVR: Over a Decade of Practice
Temporal Trends in Patient Characteristics and Clinical Outcomes of TAVR: Over a Decade of Practice Open
Background/Objective: Transcatheter aortic valve replacement (TAVR) is indicated for severe aortic stenosis patients with a prohibitive surgical risk. However, its use has been expanding in recent years to include intermediate- and low-ris…
View article: Analyzing aortic stenosis-related mortality before and after transcatheter aortic valve replacement approval: insights from CDC data
Analyzing aortic stenosis-related mortality before and after transcatheter aortic valve replacement approval: insights from CDC data Open
Background In recent decades, Transcatheter Aortic Valve Replacement (TAVR) has revolutionized the treatment landscape for aortic stenosis (AS). This study aimed to investigate the shifts in AS-related mortality rates before and after the …
View article: Chronic kidney disease and survival of patients with tricuspid regurgitation
Chronic kidney disease and survival of patients with tricuspid regurgitation Open
Introduction Chronic kidney disease (CKD) patients are under-represented in clinical trials examining transcatheter interventions for tricuspid regurgitation (TR). The purpose of the current analysis was to investigate how CKD modifies the…
View article: Left Atrial Appendage Occlusion versus Novel Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation—One-Year Survival
Left Atrial Appendage Occlusion versus Novel Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation—One-Year Survival Open
Aim To compare the 1-year survival rate of patients with atrial fibrillation (AF) following left atrial appendage occluder (LAAO) implantation vs. treatment with novel oral anticoagulants (NOACs). Methods: We have conducted an indirect, re…
View article: Transcatheter edge-to-edge mitral valve repair in patients with acute decompensated heart failure due to severe mitral regurgitation
Transcatheter edge-to-edge mitral valve repair in patients with acute decompensated heart failure due to severe mitral regurgitation Open
Mitral valve TEER for patients with ADHF and significant MR is safe, feasible, and achieves substantial reduction in MR severity. Despite high early mortality, procedural success is associated with good long-term clinical outcomes for pati…
View article: Body mass index, frailty and outcome of patients with significant tricuspid regurgitation
Body mass index, frailty and outcome of patients with significant tricuspid regurgitation Open
Funding Acknowledgements Type of funding sources: None. Background Body weight is associated with frailty and is an independent strong predictor of adverse outcomes among patients with cardiovascular diseases. Purpose To evaluate how body …
View article: Chronic kidney disease and outcome of patients with tricuspid regurgitation
Chronic kidney disease and outcome of patients with tricuspid regurgitation Open
Funding Acknowledgements Type of funding sources: None. Introduction Although chronic kidney disease (CKD) is common among patients with tricuspid regurgitation (TR), these patients are under-represented in clinical trials examining tricus…
View article: Virtual reality utilization for left atrial appendage occluder device size prediction
Virtual reality utilization for left atrial appendage occluder device size prediction Open
A VR visualization of the LAA ostium in different perspectives allows for a better understanding of its funnel-shaped structure. VR measurement of the maximal ostium diameter had the strongest correlation with the diameter of the inserted …
View article: Management and outcome of patients with non-ST elevation myocardial infarction and intercurrent non-coronary precipitating events
Management and outcome of patients with non-ST elevation myocardial infarction and intercurrent non-coronary precipitating events Open
Aims To evaluate the effect of an intercurrent non-coronary illness on the management and outcome of patients with non-ST-segment elevation myocardial infarction (NSTEMI). Methods and results Consecutive hospitalized patients with a primar…
View article: Left atrial size predicts long-term outcome after balloon mitral valvuloplasty
Left atrial size predicts long-term outcome after balloon mitral valvuloplasty Open
Despite being a relatively low-volume center, excellent short and long-term results were demonstrated, with event-free survival rates consistent with previous studies from high-volume centers. LAVI independently predicted long-term event-f…
View article: Large multicenter evaluation of clinical outcomes of transcatheter aortic valve implantation in different age groups: results from the Israeli TAVI registry
Large multicenter evaluation of clinical outcomes of transcatheter aortic valve implantation in different age groups: results from the Israeli TAVI registry Open
Introduction Transcatheter aortic valve implantation (TAVI) is becoming the preferred treatment for elderly patients with severe aortic stenosis. Clinical outcomes of these patients according to different age groups and especially in the v…
View article: Procedural and long‐term outcome among patients undergoing expedited trans‐catheter aortic valve replacement
Procedural and long‐term outcome among patients undergoing expedited trans‐catheter aortic valve replacement Open
Objective Patients with rapidly deteriorating clinical status due to severe aortic stenosis are often referred for expedited transcatheter aortic valve replacement (TAVR). Data regarding the outcome of such interventions is limited. We aim…
View article: Table of Contents
Table of Contents Open
View article: Clinical Predictors for Procedural Stroke and Implications for Embolic Protection Devices during TAVR: Results from the Multicenter Transcatheter Aortic Valve Replacement In-Hospital Stroke (TASK) Study
Clinical Predictors for Procedural Stroke and Implications for Embolic Protection Devices during TAVR: Results from the Multicenter Transcatheter Aortic Valve Replacement In-Hospital Stroke (TASK) Study Open
Background: Data to support the routine use of embolic protection devices for stroke prevention during transcatheter aortic valve replacement (TAVR) are controversial. Identifying patients at high risk for peri-procedural cerebrovascular e…
View article: Local Anesthesia versus Conscious Sedation among Patients Undergoing Transcatheter Aortic Valve Implantation—A Propensity Score Analysis
Local Anesthesia versus Conscious Sedation among Patients Undergoing Transcatheter Aortic Valve Implantation—A Propensity Score Analysis Open
Background: Conscious sedation (CS) has been used successfully to treat patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) and as such is considered the standard anesthesia method. The local…
View article: Hemodynamic Changes After Left Ventricular Assist Device Implantation Among Heart Failure Patients With and Without Elevated Pulmonary Vascular Resistance
Hemodynamic Changes After Left Ventricular Assist Device Implantation Among Heart Failure Patients With and Without Elevated Pulmonary Vascular Resistance Open
Background Left ventricular assist devices (LVADs) may reverse elevated pulmonary vascular resistance (PVR) which is associated with worse prognosis in heart failure (HF) patients. We aim to describe the temporal changes in hemodynamic par…
View article: Diastolic Plateau – Invasive Hemodynamic Marker of Adverse Outcome Among Left Ventricular Assist Device Patients
Diastolic Plateau – Invasive Hemodynamic Marker of Adverse Outcome Among Left Ventricular Assist Device Patients Open
Background Diastolic plateau is an invasive hemodynamic marker of impaired right ventricular (RV) diastolic filling. The purpose of the current analysis was to evaluate the prognostic importance of this sign in left ventricular assist devi…
View article: Impact of Valve Size on Paravalvular Leak and Valve Hemodynamics in Patients With Borderline Size Aortic Valve Annulus
Impact of Valve Size on Paravalvular Leak and Valve Hemodynamics in Patients With Borderline Size Aortic Valve Annulus Open
Background Transcatheter heart valve (THV) selection for transcatheter aortic valve implantation (TAVI) is crucial to achieve procedural success. Borderline aortic annulus size (BAAS), which allows a choice between two consecutive valve si…
View article: Invasive management in elderly patients with non-ST elevation myocardial infarction is beneficial regardless of frailty status
Invasive management in elderly patients with non-ST elevation myocardial infarction is beneficial regardless of frailty status Open
Introduction Elderly patients are underrepresented in clinical trials evaluating the management of non-ST elevation myocardial infarction (NSTEMI) patients. Moreover, frailty status is often not reported in these trials. Purpose To evaluat…
View article: Clinical and echocardiographic parameters associated with left ventricular recovery after TAVI
Clinical and echocardiographic parameters associated with left ventricular recovery after TAVI Open
Introduction The relationship between severe Aortic Stenosis (AS) and Left Ventricular (LV) dysfunction is well established. However, there is a paucity of data regarding LV functional recovery after TAVI. Purpose To study the clinical and…
View article: Permanent pacemaker implantation post transcatheter aortic valve replacement- the role of pacing burden
Permanent pacemaker implantation post transcatheter aortic valve replacement- the role of pacing burden Open
Introduction Previous studies have provided inconsistent results regarding the clinical impact of new permanent pacemaker (PPM) post TAVR. Our aim is to evaluate whether new PPM post TAVR is associated with higher 1-year mortality and/or h…
View article: Pseudo-discordance mimicking low-flow low-gradient aortic stenosis in transcatheter aortic valve replacement patients with severe symptomatic aortic stenosis
Pseudo-discordance mimicking low-flow low-gradient aortic stenosis in transcatheter aortic valve replacement patients with severe symptomatic aortic stenosis Open
Discordant echocardiographic findings are commonly found in patients with symptomatic AS. Underestimation of the true mean gradient due to technical difficulties is an important cause of these discrepant findings. LVOT area by echocardiogr…
View article: Clinical Outcome and Safety of Transcaval Access for Transcatheter Aortic Valve Replacement as Compared to Other Alternative Approaches
Clinical Outcome and Safety of Transcaval Access for Transcatheter Aortic Valve Replacement as Compared to Other Alternative Approaches Open
Background: A small proportion of patients in need of transcatheter aortic valve replacement (TAVR) are not suitable for the transfemoral approach due to peripheral artery disease. Alternative TAVR approaches are associated with short- and…