Itamar Terem
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View article: Exercise modulates brain pulsatility: insights from q-aMRI and MRI-based flow methods
Exercise modulates brain pulsatility: insights from q-aMRI and MRI-based flow methods Open
This study investigates intracranial dynamics following the Monro–Kellie doctrine, depicting how brain pulsatility, cerebrospinal fluid (CSF) flow and cerebral blood flow (CBF) interact under resting and exercise conditions. Using quantita…
View article: Dynamic visualization of brain pulsations using amplified MRI: methodology and applications
Dynamic visualization of brain pulsations using amplified MRI: methodology and applications Open
Brain pulsatility offers a compelling application in the study of cerebral biomechanics, particularly for mild traumatic brain injury (mTBI) and elevated intracranial pressure (ICP). In this study, we used amplified MRI to quantify brain t…
View article: 3D Quantitative-Amplified Magnetic Resonance Imaging (3D q-aMRI)
3D Quantitative-Amplified Magnetic Resonance Imaging (3D q-aMRI) Open
Amplified MRI (aMRI) is a promising new technique that can visualize pulsatile brain tissue motion by amplifying sub-voxel motion in cine MRI data, but it lacks the ability to quantify the sub-voxel motion field in physical units. Here, we…
View article: Noninvasive virtual biopsy using micro-registered optical coherence tomography (OCT) in human subjects
Noninvasive virtual biopsy using micro-registered optical coherence tomography (OCT) in human subjects Open
Histological hematoxylin and eosin–stained (H&E) tissue sections are used as the gold standard for pathologic detection of cancer, tumor margin detection, and disease diagnosis. Producing H&E sections, however, is invasive and time-consumi…
View article: Quantitative comparison between aMRI and DENSE for the assessment of brain tissue motion
Quantitative comparison between aMRI and DENSE for the assessment of brain tissue motion Open
Purpose Amplified MRI (aMRI) holds potential for assessing brain tissue motion and strain, using images acquired from readily-available sequences. However, image registration is necessary to extract displacements from the motion-amplified …
View article: Increased Hindbrain Motion in Chiari Malformation I Patients Measured Through 3D Amplified MRI (3D aMRI)
Increased Hindbrain Motion in Chiari Malformation I Patients Measured Through 3D Amplified MRI (3D aMRI) Open
Chiari Malformation type 1 (CM-I) is a neurological disorder characterized by morphological defects such as excessive cerebral tonsils herniation and vast associated symptomatology. Given that these structural defects cannot explain the un…
View article: Intravital 3D visualization and segmentation of murine neural networks at micron resolution
Intravital 3D visualization and segmentation of murine neural networks at micron resolution Open
View article: 3D amplified MRI (aMRI)
3D amplified MRI (aMRI) Open
Purpose Amplified MRI (aMRI) has been introduced as a new method of detecting and visualizing pulsatile brain motion in 2D. Here, we improve aMRI by introducing a novel 3D aMRI approach. Methods 3D aMRI was developed and tested for its abi…
View article: OCT2Hist: Non-Invasive Virtual Biopsy Using Optical Coherence Tomography
OCT2Hist: Non-Invasive Virtual Biopsy Using Optical Coherence Tomography Open
Histological haematoxylin and eosin–stained (H&E) tissue sections are used as the gold standard for pathologic detection of cancer, tumour margin detection, and disease diagnosis 1 . Producing H&E sections, however, is invasive and time-co…
View article: Development, calibration, and testing of 3D amplified MRI (aMRI) for the quantification of intrinsic brain motion
Development, calibration, and testing of 3D amplified MRI (aMRI) for the quantification of intrinsic brain motion Open
Microvascular blood volume pulsations, combined with CSF circulation result in subtle deformation of the brain during each heartbeat. To visualize and quantify these small deformations, an image processing technique called amplified MRI (a…
View article: Novel strain analysis informs about injury susceptibility of the corpus callosum to repeated impacts
Novel strain analysis informs about injury susceptibility of the corpus callosum to repeated impacts Open
Increasing evidence for the cumulative effects of head trauma on structural integrity of the brain has emphasized the need to understand the relationship between tissue mechanic properties and injury susceptibility. Here, diffusion tensor …
View article: Issue Information
Issue Information Open