Wakako Ito
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View article: Effects of Extended‐Release Methylphenidate on Dopamine and Norepinephrine Transporters in Adults With Attention‐Deficit/Hyperactivity Disorder: A Longitudinal Dual‐Tracer <scp>PET</scp> Study
Effects of Extended‐Release Methylphenidate on Dopamine and Norepinephrine Transporters in Adults With Attention‐Deficit/Hyperactivity Disorder: A Longitudinal Dual‐Tracer <span>PET</span> Study Open
Aim Attention‐deficit/hyperactivity disorder (ADHD) is associated with dysregulation of dopamine and norepinephrine neurotransmission. Extended‐release methylphenidate (MPH), a first‐line treatment for ADHD, modulates these systems. Howeve…
View article: Subjective and Objective Sleepiness Indices in Idiopathic Hypersomnia, Narcolepsy, and Healthy Controls
Subjective and Objective Sleepiness Indices in Idiopathic Hypersomnia, Narcolepsy, and Healthy Controls Open
日中の眠気を正しく評価し解釈することは睡眠問題の予防や心身の健康維持という観点からも極めて重要であり,健常から疾患レベルまでその特徴を包括的に把握する必要がある。本研究では眠気の主観指標と客観指標を併用し,過眠症患者を含む若年成人の日中の眠気について検討した。睡眠検査を行った成人男女42名で,内訳は健常対照群(HC)が19名,特発性過眠症群(IH)が13名,ナルコレプシー群(NA)が10名であった。HC群においては主観的眠気尺度である日本語版エプワース眠気尺度(Epwort…
View article: Changes in sleep profile on exposure to sodium chloride and artificially carbonated springs: a pilot study
Changes in sleep profile on exposure to sodium chloride and artificially carbonated springs: a pilot study Open
[Purpose] Herein, we aimed to investigate the effects of bathing in a sodium chloride spring and an artificially carbonated spring on core body temperature and electroencephalograms, to assess whether the springs facilitate sleep. [Partici…
View article: 0400 Sleep Onset REM Period (SOREMP); Beyond the Diagnostic Marker
0400 Sleep Onset REM Period (SOREMP); Beyond the Diagnostic Marker Open
Introduction Shortened mean sleep latency and multiple Sleep Onset REM Period (SOREMP) on MSLT has been used as a characteristic marker for narcolepsy and incorporated in all editions of International Classification of Sleep Disorders. Epi…
View article: 511 Pathological sleep prolongation and sleep onset REM period
511 Pathological sleep prolongation and sleep onset REM period Open
Introduction ICSD-3 employs two definitions of pathological sleepiness: sleep prolongation with 24-hour total sleep time (24hrPSG TST) ≥660 and high sleep propensity with mean sleep latency(mSL) ≤8 min on MSLT. Multiple SOREMPs on MSLT ref…
View article: Sleep Debt and Social Jetlag Associated with Sleepiness, Mood, and Work Performance among Workers in Japan
Sleep Debt and Social Jetlag Associated with Sleepiness, Mood, and Work Performance among Workers in Japan Open
Although sleep debt and social jetlag (SJL) influence daytime dysfunctions, the effects of both sleep debt and SJL on them have not been analyzed. The aim of this study was to examine the mutual relationship between sleep debt and SJL on d…
View article: Evaluation of pathological sleepiness by <scp>M</scp>ultiple <scp>S</scp>leep <scp>L</scp>atency <scp>T</scp>est and 24‐hour polysomnography in patients suspected of idiopathic hypersomnia
Evaluation of pathological sleepiness by <span>M</span>ultiple <span>S</span>leep <span>L</span>atency <span>T</span>est and 24‐hour polysomnography in patients suspected of idiopathic hypersomnia Open
Sleepiness is considered not to be unidimensional. The International Classification of Sleep Disorders, 3rd edition (ICSD-3) employs two criteria for 'pathological sleepiness' for idiopathic hypersomnia: (i) sleep prolongation with a 24-h …
View article: 0595 MSLT AND 24hr PSG for Diagnosing Idiopathic Hypersomnia
0595 MSLT AND 24hr PSG for Diagnosing Idiopathic Hypersomnia Open
MSLT evaluates the ability to fall asleep in daytime nap opportunities, serving as the gold standard for the diagnosis of narcolepsy type 1. However, recent studies suggest the limitation of MSLT for the diagnosis of other hypersomnias. IC…
View article: 0632 Analysis of Sleep Bout Duration: A New Marker to Differentiate Narcolepsy Type 1
0632 Analysis of Sleep Bout Duration: A New Marker to Differentiate Narcolepsy Type 1 Open
Recent studies reported the diagnostic value of sequential occurrence of sleep stages (stage transition) in addition to the conventional sleep macrostructure (sleep onset REM period) for diagnosis of narcolepsy type 1. However these analys…
View article: 0660 SUBGROUP OF NARCOLEPSY TYPE 2: CHARACTERISTICS OF SLEEP VARIABLES IN HYPERSOMNIA PATIENTS WITH ATTENTION-DEFICIT HYPERACTIVITY DISORDER (ADHD)
0660 SUBGROUP OF NARCOLEPSY TYPE 2: CHARACTERISTICS OF SLEEP VARIABLES IN HYPERSOMNIA PATIENTS WITH ATTENTION-DEFICIT HYPERACTIVITY DISORDER (ADHD) Open
Patients with attention-deficit hyperactivity disorder (ADHD) have been reported to suffer from subjective and objective sleepiness, and sleepiness is suggested to have pathophysiological relevance to ADHD. Narcolepsy type 2 is reported to…
View article: 0659 FREQUENT CRAVING FOR SWEETS AT WAKE UP IS ASSOCIATED WITH SUBJECTIVE NOCTURNAL AWAKENING AND SLEEP STAGE TRANSITION INDEX IN PATIENTS WITH NARCOLEPSY TYPE 1
0659 FREQUENT CRAVING FOR SWEETS AT WAKE UP IS ASSOCIATED WITH SUBJECTIVE NOCTURNAL AWAKENING AND SLEEP STAGE TRANSITION INDEX IN PATIENTS WITH NARCOLEPSY TYPE 1 Open
Body mass index independent metabolic abnormalities are reportedly associated with narcolepsy. We found that abnormal fatty acid metabolism is involved in the pathophysiology of narcolepsy and other hypersomnia, and appeared to be associat…
View article: 0661 EXCESSIVE DAYTIME SLEEPINESS IN ADULTS WITH POSSIBLE ATTENTION DEFICIT/HPERACTIVITY DISORDER (ADHD): A WEB-BASED CROSS-SECTIONAL STUDY
0661 EXCESSIVE DAYTIME SLEEPINESS IN ADULTS WITH POSSIBLE ATTENTION DEFICIT/HPERACTIVITY DISORDER (ADHD): A WEB-BASED CROSS-SECTIONAL STUDY Open
Arousal dysregulation has been speculated to be involved in the pathological mechanism of attention deficit/hyperactivity disorder (ADHD). However, there has been no epidemiological study assessing the real condition of excessive daytime s…