Itzel Alejandra Hernández-Romero
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View article: Mapping early PRC2 nucleation sites upon Suz12 reintroduction reveals features of <i>de novo</i> Polycomb recruitment
Mapping early PRC2 nucleation sites upon Suz12 reintroduction reveals features of <i>de novo</i> Polycomb recruitment Open
Polycomb domains safeguard cell identity by maintaining lineage-specific chromatin states enriched in repressive histone modifications, preserving the epigenetic memory of cell lineages. While Polycomb Repressive Complex 2 (PRC2) can re-es…
View article: De Novo Polycomb Recruitment and Repressive Domain Formation
De Novo Polycomb Recruitment and Repressive Domain Formation Open
Every cell of an organism shares the same genome; even so, each cellular lineage owns a different transcriptome and proteome. The Polycomb group proteins (PcG) are essential regulators of gene repression patterning during development and h…
View article: The Regulatory Roles of Non-coding RNAs in Angiogenesis and Neovascularization From an Epigenetic Perspective
The Regulatory Roles of Non-coding RNAs in Angiogenesis and Neovascularization From an Epigenetic Perspective Open
Angiogenesis is a crucial process for organ morphogenesis and growth during development, and it is especially relevant during the repair of wounded tissue in adults. It is coordinated by an equilibrium of pro- and anti-angiogenic factors; …