Ivan A. Yaremenko
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View article: <i>N</i>‐Substituted Bridged Azaozonides as Promising Antimalarial Agents
<i>N</i>‐Substituted Bridged Azaozonides as Promising Antimalarial Agents Open
Forty‐five aminoperoxides belonging to bridged azaozonides, bridged N ‐substituted azaozonides, and tricyclic aminoperoxides were evaluated for in vitro antimalarial activity against Plasmodium falciparum (3D7) and for cytotoxicity against…
View article: Contents list
Contents list Open
View article: Peroxide derivatives as SARS-CoV-2 entry inhibitors
Peroxide derivatives as SARS-CoV-2 entry inhibitors Open
View article: Cyclic Organic Peroxides as New Fungicides against Phytopathogenic Fungi
Cyclic Organic Peroxides as New Fungicides against Phytopathogenic Fungi Open
The search for new classes of fungicides has long been important in plant protection due to the development of fungal resistance to currently used agrochemicals. Organic peroxides have long been regarded as exotic and unstable compounds. T…
View article: Bridged 1,2,4-Trioxolanes: SnCl4—Catalyzed Synthesis and an In Vitro Study against S. mansoni
Bridged 1,2,4-Trioxolanes: SnCl4—Catalyzed Synthesis and an In Vitro Study against S. mansoni Open
A synthesis of bridged 1,2,4-trioxolanes (bridged ozonides) from 1,5-diketones and hydrogen peroxide catalyzed by SnCl4 was developed. It was shown that the ratio of target ozonides can be affected by the application of SnCl4 as a catalyst…
View article: 1-(2-Benzyl-1,5-dimethyl-6,7,8-trioxabicyclo[3.2.1]octan-2-yl)ethan-1-ol
1-(2-Benzyl-1,5-dimethyl-6,7,8-trioxabicyclo[3.2.1]octan-2-yl)ethan-1-ol Open
The title compound, 1-(2-Benzyl-1,5-dimethyl-6,7,8-trioxabicyclo[3.2.1]octan-2-yl)ethan-1-ol, was synthesized for the first time by the selective reduction in keto ozonide under the action of the strong reducing agent LiAlH4. The product w…
View article: FERROTSENNING AYRIM SPIRTLARI SINTEZI
FERROTSENNING AYRIM SPIRTLARI SINTEZI Open
Mazkur maqolada ferrotsenning ayrim spirtlari sintezi o‘rganilgan. Kvant-kimyoviy hisoblashlar natijalari eksperimental natijalar bilan solishtirilgan. Olingan mahsulotlarning tuzilishi YaMR spektroskopiya bilan aniqlangan.
View article: Lewis Acids and Heteropoly Acids in the Synthesis of Organic Peroxides
Lewis Acids and Heteropoly Acids in the Synthesis of Organic Peroxides Open
Organic peroxides are an important class of compounds for organic synthesis, pharmacological chemistry, materials science, and the polymer industry. Here, for the first time, we summarize the main achievements in the synthesis of organic p…
View article: Development of Biodegradable Delivery Systems Containing Novel 1,2,4-Trioxolane Based on Bacterial Polyhydroxyalkanoates
Development of Biodegradable Delivery Systems Containing Novel 1,2,4-Trioxolane Based on Bacterial Polyhydroxyalkanoates Open
In this work, delivery systems in the form of microparticles and films containing 1,2,4-trioxolane (ozonide, OZ) based on polyhydroxyalkanoates (PHAs) were developed. Main systems’ characteristics were investigated: the particle yield, ave…
View article: Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide‐Based Hybrid Compounds against SARS‐CoV‐2 and Cancer
Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide‐Based Hybrid Compounds against SARS‐CoV‐2 and Cancer Open
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) cause life‐threatening diseases in millions of people worldwide, in particular, in patients with cancer, and there is an urgent need for antiviral agents agains…
View article: Artemisinin and Quinoline Hybrid Compounds Inhibit Replication of SARS-CoV-2 In Vitro
Artemisinin and Quinoline Hybrid Compounds Inhibit Replication of SARS-CoV-2 In Vitro Open
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cause life-threatening diseases in millions of people worldwide and there is an urgent need for antiviral agents against this infection. While in vitro activiti…
View article: Artemisinin and Quinoline Hybrid Compounds Inhibit Replication of SARS-CoV-2 In Vitro
Artemisinin and Quinoline Hybrid Compounds Inhibit Replication of SARS-CoV-2 In Vitro Open
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cause life-threatening diseases in millions of people worldwide and there is an urgent need for antiviral agents against this infection. While in vitro activiti…
View article: Correction: Stereoelectronic power of oxygen in control of chemical reactivity: the anomeric effect is not alone
Correction: Stereoelectronic power of oxygen in control of chemical reactivity: the anomeric effect is not alone Open
Correction for ‘Stereoelectronic power of oxygen in control of chemical reactivity: the anomeric effect is not alone’ by Igor V. Alabugin et al. , Chem. Soc. Rev. , 2021, DOI: 10.1039/d1cs00386k.
View article: Application of BF3·Et2O in the synthesis of cyclic organic peroxides (microreview)
Application of BF3·Et2O in the synthesis of cyclic organic peroxides (microreview) Open
View article: Front Cover: Synthetic Peroxides Promote Apoptosis of Cancer Cells by Inhibiting P‐Glycoprotein ABCB5 (ChemMedChem 13/2020)
Front Cover: Synthetic Peroxides Promote Apoptosis of Cancer Cells by Inhibiting P‐Glycoprotein ABCB5 (ChemMedChem 13/2020) Open
The Front Cover shows the effort of three collaborators from Thailand (BIOTEC), Macau (MUST), and Russia (Zelinsky Institute of Organic Chemistry RAS) on the discovery of promising anticancer agents based on synthetic peroxides. Multidrug …
View article: Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees
Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees Open
In recent years, the number of pollinators in the world has significantly decreased. A possible reason for this is the toxic effects of agrochemicals reducing the immunity of insects that leads to their increased susceptibility to pathogen…
View article: Cover Feature: Catalyst Development for the Synthesis of Ozonides and Tetraoxanes Under Heterogeneous Conditions: Disclosure of an Unprecedented Class of Fungicides for Agricultural Application (Chem. Eur. J. 21/2020)
Cover Feature: Catalyst Development for the Synthesis of Ozonides and Tetraoxanes Under Heterogeneous Conditions: Disclosure of an Unprecedented Class of Fungicides for Agricultural Application (Chem. Eur. J. 21/2020) Open
A catalyst for the synthesis of ozonides and tetraoxanes under heterogeneous conditions was developed. This work reports an unprecedented class of fungicides with significant potential for agricultural applications. More information can be…
View article: Phytomedicinal aspects of sesquiterpenoid peroxides: Origin, structures and biological activity
Phytomedicinal aspects of sesquiterpenoid peroxides: Origin, structures and biological activity Open
View article: Corrigendum: Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity
Corrigendum: Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity Open
On page 904, at the bottom of Table 2, the A549 IC 50 value and selectivity index (SI) for paclitaxel are switched.T he correct entries are:IC 50 = 0.003 mm and SI = 33.2.
View article: Front Cover: Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity (ChemMedChem 9/2018)
Front Cover: Novel Peroxides as Promising Anticancer Agents with Unexpected Depressed Antimalarial Activity (ChemMedChem 9/2018) Open
The Front Cover shows the effort of three collaborators from Thailand (BIOTEC), Macau (MUST), and Russia (Zelinsky Institute) on the discovery of novel anticancer and antimalarial compounds. The present findings showed for the first time p…
View article: Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions
Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions Open
The biological activity of organic peroxides is usually associated with the antimalarial properties of artemisinin and its derivatives. However, the analysis of published data indicates that organic peroxides exhibit a variety of biologica…
View article: Synthetic Strategies for Peroxide Ring Construction in Artemisinin
Synthetic Strategies for Peroxide Ring Construction in Artemisinin Open
The present review summarizes publications on the artemisinin peroxide fragment synthesis from 1983 to 2016. The data are classified according to the structures of a precursor used in the key peroxidation step of artemisinin peroxide cycle…
View article: CCDC 1499580: Experimental Crystal Structure Determination
CCDC 1499580: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1499579: Experimental Crystal Structure Determination
CCDC 1499579: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Rearrangements of organic peroxides and related processes
Rearrangements of organic peroxides and related processes Open
This review is the first to collate and summarize main data on named and unnamed rearrangement reactions of peroxides. It should be noted, that in the chemistry of peroxides two types of processes are considered under the term rearrangemen…