Ivan Bergo
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View article: The Interconnected World of Coagulation Factors, Platelets and Plasminogen: A Novel Perspective on Biosynthetic Regulation
The Interconnected World of Coagulation Factors, Platelets and Plasminogen: A Novel Perspective on Biosynthetic Regulation Open
Platelets play a pivotal role in coagulation, traditionally recognized for their involvement in thrombin generation via the prothrombinase complex and for regulating thrombopoietin (TPO) synthesis through platelet-mediated TPO uptake. Howe…
View article: Utilization of lipoxins and other specialised pro-resolving mediators in the prevention and treatment of diabetic nephropathy and diabetic cardiovascular disease
Utilization of lipoxins and other specialised pro-resolving mediators in the prevention and treatment of diabetic nephropathy and diabetic cardiovascular disease Open
Diabetes mellitus type 2 is a chronic disease caused by insulin resistance. Whilst first originating in the adipose tissue, this pathophysiological process later affects the muscles and the liver as well. This induces high plasma levels of…
View article: Hormone Imbalance in Polycystic Ovarian Syndrome
Hormone Imbalance in Polycystic Ovarian Syndrome Open
Polycystic Ovarian Syndrome (PCOS) is a disease that is characterized by an increased Gonadotropin-Releasing-Hormone (GnRH) pulsatile frequency, causing an altered LH/FSH ratio. More precisely an increased Luteinizing Hormone (LH) secretio…