Iván D. Flórez
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View article: Relationship between paediatricians and the pharmaceutical and commercial milk formula industries: an explanatory mixed methods study
Relationship between paediatricians and the pharmaceutical and commercial milk formula industries: an explanatory mixed methods study Open
Objective To describe and understand relationships between paediatricians and industry in Colombia. Methods Mixed methods study composed of three phases: quantitative (cross-sectional study, e-survey to paediatricians) describing interacti…
View article: Sucrose or glucose compared to breast milk for pain control in preterm infants: a systematic review and meta-analysis
Sucrose or glucose compared to breast milk for pain control in preterm infants: a systematic review and meta-analysis Open
The aim of this systematic review/meta-analysis of randomized clinical trials (RCTs) was to determine the efficacy of sucrose or glucose (SG) in preterm infants requiring heel lancing and venipuncture compared to breast milk or expressed b…
View article: Non-invasive respiratory support in pediatric patients with acute hypoxemic respiratory failure: a systematic review and network meta-analysis of randomized controlled trials
Non-invasive respiratory support in pediatric patients with acute hypoxemic respiratory failure: a systematic review and network meta-analysis of randomized controlled trials Open
This study was funded by the Foundation of the First Hospital of Lanzhou University (ldyyyn2023-16), the Gansu Provincial Health Industry Scientific Research Project (GSWSKY2024-18), the Natural Science Foundation of Gansu Province (25JRRA…
View article: Human Trafficking Detection in Health Care Settings: A Scoping Review
Human Trafficking Detection in Health Care Settings: A Scoping Review Open
Objectives This scoping review aimed to identify available tools for detecting human trafficking survivors in healthcare settings and to explore implementation strategies. Methods A systematic search was conducted in MEDLINE/PubMed, EMBASE…
View article: Consolidation, Systematic Appraisal and Comparison of Guideline Recommendations Regarding Management of Chronic Pain: Protocol for a Digital Chronic Pain Recommendation Map
Consolidation, Systematic Appraisal and Comparison of Guideline Recommendations Regarding Management of Chronic Pain: Protocol for a Digital Chronic Pain Recommendation Map Open
Introduction Chronic pain affects 1 in 5 adults and children globally; however, management remains highly variable and low value care is common. Inconsistent recommendations among clinical practice guidelines for management of chronic pain…
View article: Safety and effectiveness of opioid use in adult patients presenting to emergency services with suspected acute appendicitis: a protocol for a systematic review of the literature and network meta-analysis
Safety and effectiveness of opioid use in adult patients presenting to emergency services with suspected acute appendicitis: a protocol for a systematic review of the literature and network meta-analysis Open
Introduction Acute abdominal pain is a chief complaint in emergency departments and represents 7%–10% of emergency room (ER) visits. Acute appendicitis represents 15% of the causes of abdominal pain and 62% of the causes that require surgi…
View article: Egyptian pediatric guidelines for the management of childhood venous thromboembolism: the adapted methodology: a limited resource country perspective
Egyptian pediatric guidelines for the management of childhood venous thromboembolism: the adapted methodology: a limited resource country perspective Open
In general, a complete clinical and radiological assessment and some laboratory tests are indicated at the initial diagnosis to confirm a thrombotic disorder and to further choose the type of workup required. Future research should report …
View article: Evaluating the Quality of Guidelines Using the AGREE II Tool by a Large Language Model vs Human Appraisers
Evaluating the Quality of Guidelines Using the AGREE II Tool by a Large Language Model vs Human Appraisers Open
This quality improvement study examines the efficacy of a large language model to evaluate guidelines for therapeutic drug monitoring compared with human apparaisers.
View article: Core GRADE 6: presenting the evidence in summary of findings tables
Core GRADE 6: presenting the evidence in summary of findings tables Open
This sixth article in a seven part series presents the Core GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach to summary of findings tables. These tables provide essential information about the effects of i…
View article: Core GRADE 4: rating certainty of evidence—risk of bias, publication bias, and reasons for rating up certainty
Core GRADE 4: rating certainty of evidence—risk of bias, publication bias, and reasons for rating up certainty Open
This fourth article in a seven part series presents the Core GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach to addressing risk of bias, publication bias, and rating up certainty. In Core GRADE, randomise…
View article: Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children: a Cochrane review
Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children: a Cochrane review Open
View article: An international guideline training and certification programme
An international guideline training and certification programme Open
View article: A cross‐sectional review of policies on conflicts of interest and funding in the development manuals of practice guidelines
A cross‐sectional review of policies on conflicts of interest and funding in the development manuals of practice guidelines Open
Importance Policies on conflicts of interest (COI) and funding are essential to reduce the risk of bias in the guideline development process. Objective To collate and review the content related to COI and funding policies from guideline de…
View article: Guía de práctica clínica para la evaluación, tratamiento y seguimiento de niños contacto de pacientes con tuberculosis pulmonar en Colombia
Guía de práctica clínica para la evaluación, tratamiento y seguimiento de niños contacto de pacientes con tuberculosis pulmonar en Colombia Open
Introducción: Las guías de práctica clínica (GPC) disponibles sobre infección latente por tuberculosis (ILTB) no son exclusivas de población pediátrica. Objetivo: Desarrollar recomendaciones basadas en evidencia para evaluación, tratamient…
View article: Uptake of core outcome sets in paediatric clinical trials: a protocol
Uptake of core outcome sets in paediatric clinical trials: a protocol Open
Introduction A growing number of paediatric core outcome sets (COS) have been developed in the past 20 years. Previous studies have provided many useful insights into the uptake of COS. In addition to the awareness of COS among clinical tr…
View article: Cost-effectiveness analysis comparing QuantiFERON test and tuberculin skin test for the diagnosis of latent tuberculosis infection in immunocompetent children under 15 years of age in Colombia
Cost-effectiveness analysis comparing QuantiFERON test and tuberculin skin test for the diagnosis of latent tuberculosis infection in immunocompetent children under 15 years of age in Colombia Open
Objective To determine the cost-effectiveness of the QuantiFERON (QFT) test versus the tuberculin skin test (TST) in diagnosing latent tuberculosis infection (LTBI) in immunocompetent children under 15 years of age who are in contact with …
View article: Influence of time of birth in early neonatal mortality and morbidity: retrospective cohort study
Influence of time of birth in early neonatal mortality and morbidity: retrospective cohort study Open
Background A key target of the 2030 Sustainable Development Goals is to eliminate preventable deaths in newborns and children under 5. This study aimed to estimate the effect of time of birth on early neonatal mortality (ENM) and low Apgar…
View article: Scoping review indicates heterogeneous methods for developing and integrating patient decision aids in the context of clinical practice guidelines
Scoping review indicates heterogeneous methods for developing and integrating patient decision aids in the context of clinical practice guidelines Open
We identified heterogeneous methods for developing and integrating PDAs based on CPG recommendations. Empirical testing is required to determine the most useful and practically feasible (combination of) methods. CPG organizations should fo…
View article: Comparative Effects of Obesity Medications for Adults Living with Obesity: A Systematic Review and Network Meta-Analysis
Comparative Effects of Obesity Medications for Adults Living with Obesity: A Systematic Review and Network Meta-Analysis Open
View article: Advancing quality appraisal for living practice guidelines: A scoping review
Advancing quality appraisal for living practice guidelines: A scoping review Open
View article: Fostering innovation and advancement in evidence‐based practice and guidelines within the field of pediatrics: The 2024 BRIGHT declaration
Fostering innovation and advancement in evidence‐based practice and guidelines within the field of pediatrics: The 2024 BRIGHT declaration Open
The first Better evidence and RecommendatIons for the next Generation HealTh—BRIGHT symposium was held in Chongqing, China between June 21 and 23, 2024. The symposium did not only showcase the recent progress made by multidisciplinary team…
View article: Diagnostic accuracy of the point-of-care standard G6PD test™ (SD Biosensor) for glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysis
Diagnostic accuracy of the point-of-care standard G6PD test™ (SD Biosensor) for glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysis Open
View article: Effects of active breaks on educational achievement in children with and without ADHD: study protocol and rationale of the Break4Brain project
Effects of active breaks on educational achievement in children with and without ADHD: study protocol and rationale of the Break4Brain project Open
The Break4Brain project aims to elucidate the effects of both acute and chronic physical activity (PA) on educational achievement in children with and without Attention Deficit Hyperactivity Disorder (ADHD). This study will be conducted in…
View article: Topical Nasal Steroids for Allergic Rhinitis in Children. Is One Better Than the Others? Protocol for a Systematic Review and Network Meta-analysis.
Topical Nasal Steroids for Allergic Rhinitis in Children. Is One Better Than the Others? Protocol for a Systematic Review and Network Meta-analysis. Open
Background The present protocol is registered in the International Prospective Register of Systematic Reviews PROSPERO under de ID code CRD42023476313, and adheres the PRISMA-P 2015 statement. The complete checklist can be consulted in the…
View article: Editorial: The relevance of core outcome sets to clinical guideline development
Editorial: The relevance of core outcome sets to clinical guideline development Open
View article: Fostering Shared Decision-Making Between Patients and Health Care Professionals in Clinical Practice Guidelines: Protocol for a Project to Develop and Test a Tool for Guideline Developers
Fostering Shared Decision-Making Between Patients and Health Care Professionals in Clinical Practice Guidelines: Protocol for a Project to Develop and Test a Tool for Guideline Developers Open
Background Clinical practice guidelines (CPGs) are designed to assist health care professionals in medical decision-making, but they often lack effective integration of shared decision-making (SDM) principles to reflect patient values and …
View article: Introduction to the series “GRADE in Spanish”: Basic articles about the use of evidence in clinical practice
Introduction to the series “GRADE in Spanish”: Basic articles about the use of evidence in clinical practice Open
Editorial
View article: Two decades of network meta‐analysis: Roadmap to their applications and challenges
Two decades of network meta‐analysis: Roadmap to their applications and challenges Open
Recently, Ades and colleagues discussed the controversies and advancements in network meta‐analysis (NMA) over the past two decades, discussing its reliability, assumptions, novel approaches, and provided some useful recommendations for th…
View article: Uptake of core outcome sets in pediatric clinical trials: a protocol
Uptake of core outcome sets in pediatric clinical trials: a protocol Open
Introduction A growing number of pediatric core outcome sets (COS) have been developed in the past 20 years. Previous studies have provided many useful insights into the uptake of COS. In addition to the awareness of COS among clinical tri…
View article: Reporting Conflicts of Interest and Funding in Health Care Guidelines: The RIGHT-COI&F Checklist
Reporting Conflicts of Interest and Funding in Health Care Guidelines: The RIGHT-COI&F Checklist Open
The Fundamental Research Funds for the Central Universities of China.