Ivan K. Chu
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View article: Cerebrospinal Fluid p-Tau181/Amyloid Beta 42 Ratio Identifies Lymphatic-Venous Anastomosis Patients Who Respond to and Benefit from the Surgery for Relief of Cognitive Impairment with a Diagnostic Accuracy of 0.744
Cerebrospinal Fluid p-Tau181/Amyloid Beta 42 Ratio Identifies Lymphatic-Venous Anastomosis Patients Who Respond to and Benefit from the Surgery for Relief of Cognitive Impairment with a Diagnostic Accuracy of 0.744 Open
Responders (R) and Non-Responders (NR) to lymphatic-venous anastomosis (LVA) surgery for relief of cognitive impairment show significant difference in their p-tau181/Aβ42 ratios via enzyme-linked immunosorbent assay (ELISA) of their cerebr…
View article: Understanding the Binding and Structures in Model Complexes of Polypeptides and Cofactors
Understanding the Binding and Structures in Model Complexes of Polypeptides and Cofactors Open
Competitive binding between metal cofactors and functional groups of polypeptides results in a diversity of structures and chemistries in metalloproteins. Herein, we examined elements of this competitive binding using [metal-(auxiliary lig…
View article: Structure and fragmentation chemistry of the peptide radical cations of glycylphenylalanylglycine (GFG)
Structure and fragmentation chemistry of the peptide radical cations of glycylphenylalanylglycine (GFG) Open
Herein, we explore the generation and characterization of the radical cations of glycylphenylalanylglycine, or [GFG] •+ , formed via dissociative electron-transfer reaction from the tripeptide to copper(II) within a ternary complex. A comp…
View article: Focus Issue on the 9th Asia–Oceania Mass Spectrometry Conference (AOMSC2023)
Focus Issue on the 9th Asia–Oceania Mass Spectrometry Conference (AOMSC2023) Open
ADVERTISEMENT RETURN TO ISSUEEditorialNEXTFocus Issue on the 9th Asia–Oceania Mass Spectrometry Conference (AOMSC2023)Byungoo KimByungoo KimMore by Byungoo Kim, Richard A. J. O'Hair*Richard A. J. O'HairMore by Richard A. J. O'Hair, Ivan K.…
View article: ISSUE INFORMATION ‐ ToC
ISSUE INFORMATION ‐ ToC Open
View article: Study of Potential Synergistic Effect of Probiotic Formulas on Acrylamide Reduction
Study of Potential Synergistic Effect of Probiotic Formulas on Acrylamide Reduction Open
Acrylamide (AA) is a food processing contaminant commonly found in fried and baked food products. In this study, the potential synergistic effect of probiotic formulas in reducing AA was studied. Five selected probiotic strains (Lactiplant…
View article: Study of the Efficacy of Probiotic Bacteria to Reduce Acrylamide in Food and In Vitro Digestion
Study of the Efficacy of Probiotic Bacteria to Reduce Acrylamide in Food and In Vitro Digestion Open
In this study, probiotic bacteria as a new post-processing approach to reduce acrylamide (AA) was investigated. The AA reduction ability of selected Lactobacillus strains and Bifidobacterium strains was demonstrated in (a) AA chemical solu…
View article: Mechanistic examination of C<sub>α</sub>–C<sub>β</sub> tyrosyl bond cleavage: Spectroscopic investigation of the generation of α‐glycyl radical cations from tyrosyl (glycyl/alanyl)tryptophan
Mechanistic examination of C<sub>α</sub>–C<sub>β</sub> tyrosyl bond cleavage: Spectroscopic investigation of the generation of α‐glycyl radical cations from tyrosyl (glycyl/alanyl)tryptophan Open
In this study, dissociative one‐electron transfer dissociation of [Cu II (dien)Y(G/A)W] •2+ [dien = diethylenetriamine; Y(G/A)W = tyrosyl (glycyl/alanyl)tryptophan] was used to generate the tripeptide radical cations [Y(G/A)W] •+ ; subsequ…
View article: Dissociative electron transfer of copper(<scp>ii</scp>) complexes of glycyl(glycyl/alanyl)tryptophan<i>in vacuo</i>: IRMPD action spectroscopy provides evidence of transition from zwitterionic to non-zwitterionic peptide structures
Dissociative electron transfer of copper(<span>ii</span>) complexes of glycyl(glycyl/alanyl)tryptophan<i>in vacuo</i>: IRMPD action spectroscopy provides evidence of transition from zwitterionic to non-zwitterionic peptide structures Open
Non-zwitterionic π-centered [GGWπ]˙+is formed from zwitterionic [CuII(dien)GGW]˙2+through dissociative one-electron transfer involving proton and unpaired electron migrations.
View article: Formation of n → π<sup>+</sup> interaction facilitating dissociative electron transfer in isolated tyrosine-containing molecular peptide radical cations
Formation of n → π<sup>+</sup> interaction facilitating dissociative electron transfer in isolated tyrosine-containing molecular peptide radical cations Open
IRMPD suggests existence of π-radicals of [FYGG]˙+ featuring the n → π+ interaction, which are reactive intermediates toward dissociative electron transfer.
View article: Structures of [GPGG + H – H2O]+ and [GPGG + H – H2O – NH CH2]+ ions; evidence of rearrangement prior to dissociation
Structures of [GPGG + H – H2O]+ and [GPGG + H – H2O – NH CH2]+ ions; evidence of rearrangement prior to dissociation Open
View article: Loss of water from protonated polyglycines: interconversion and dissociation of the product imidazolone ions
Loss of water from protonated polyglycines: interconversion and dissociation of the product imidazolone ions Open
Imidazolones formed from polyglycines are located at the centre of the peptide backbone and dissociate more easily than interconvert.
View article: A tricyclic pyrrolobenzodiazepine produced by Klebsiella oxytoca is associated with cytotoxicity in antibiotic-associated hemorrhagic colitis
A tricyclic pyrrolobenzodiazepine produced by Klebsiella oxytoca is associated with cytotoxicity in antibiotic-associated hemorrhagic colitis Open
Cytotoxin-producing Klebsiella oxytoca is the causative agent of antibiotic-associated hemorrhagic colitis (AAHC). Recently, the cytotoxin associated with AAHC was identified as tilivalline, a known pentacyclic pyrrolobenzodiazepine…
View article: Phosphoproteome of crab-eating macaque cerebral cortex characterized through multidimensional reversed-phase liquid chromatography/mass spectrometry with tandem anion/cation exchange columns
Phosphoproteome of crab-eating macaque cerebral cortex characterized through multidimensional reversed-phase liquid chromatography/mass spectrometry with tandem anion/cation exchange columns Open
View article: Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori
Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori Open
An integrative metalloproteomic approach to unveil the role of antimicrobial metals in general using bismuth as an example.
View article: Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy
Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy Open
View article: Correction: Corrigendum: Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy
Correction: Corrigendum: Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy Open
View article: Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy Open