Ivan Lechner
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View article: Associations and Prognostic Implications of Myocardial Tissue Injury Stages in ST-Elevation Myocardial Infarction Using the Canadian Cardiovascular Society Classification
Associations and Prognostic Implications of Myocardial Tissue Injury Stages in ST-Elevation Myocardial Infarction Using the Canadian Cardiovascular Society Classification Open
Aims The recently proposed Canadian Cardiovascular Society (CCS) classification categorizes post-infarction tissue injury into four stages, potentially improving risk stratification and guiding cardioprotective strategies. Its clinical and…
View article: Selective C-reactive protein apheresis in ST-elevation myocardial infarction: Design and rationale of the randomized CRP-STEMI trial
Selective C-reactive protein apheresis in ST-elevation myocardial infarction: Design and rationale of the randomized CRP-STEMI trial Open
CRP-STEMI, NCT04939805, is registered at https://clinicaltrials.gov/study/NCT04939805.
View article: Prediction of late left ventricular thrombus formation after ST-elevation myocardial infarction: A cardiovascular magnetic resonance study
Prediction of late left ventricular thrombus formation after ST-elevation myocardial infarction: A cardiovascular magnetic resonance study Open
View article: Association of Intramyocardial Hemorrhage With Inflammatory Biomarkers in Patients With ST-Segment Elevation Myocardial Infarction
Association of Intramyocardial Hemorrhage With Inflammatory Biomarkers in Patients With ST-Segment Elevation Myocardial Infarction Open
In patients with STEMI treated with primary PCI, inflammatory parameters including hs-CRP, WBCc, and IL-6 were significantly associated with I/R injury as defined by IMH. After adjustment for other factors, hs-CRP was the only independent …
View article: Angiographic microvascular resistance and left ventricular thrombus in STEMI: a novel predictor for early risk stratification?
Angiographic microvascular resistance and left ventricular thrombus in STEMI: a novel predictor for early risk stratification? Open
View article: Age-related outcomes in CMR versus CT-guided TAVR: a secondary analysis of a randomized clinical trial
Age-related outcomes in CMR versus CT-guided TAVR: a secondary analysis of a randomized clinical trial Open
View article: Age and sex-related outcomes in cardiovascular magnetic resonance versus computed tomography-guided transcatheter aortic valve replacement: a secondary analysis of a randomized clinical trial
Age and sex-related outcomes in cardiovascular magnetic resonance versus computed tomography-guided transcatheter aortic valve replacement: a secondary analysis of a randomized clinical trial Open
In this secondary analysis of the TAVR-CMR trial, CMR-guided TAVR was associated with similar outcomes compared with CT-guided TAVR irrespective of age and sex.
View article: Mitral annular disjunction in out-of-hospital cardiac arrest patients—a retrospective cardiac MRI study
Mitral annular disjunction in out-of-hospital cardiac arrest patients—a retrospective cardiac MRI study Open
Background Mitral annular disjunction (MAD), defined as defective attachment of the mitral annulus to the ventricular myocardium, has recently been linked to malignant arrhythmias. However, its role and prognostic significance in patients …
View article: Relation of plasma neuropeptide-Y with myocardial function and infarct severity in acute ST-elevation myocardial infarction
Relation of plasma neuropeptide-Y with myocardial function and infarct severity in acute ST-elevation myocardial infarction Open
High plasma levels of NPY, measured 24h after STEMI, were independently associated with lower LVEF, decreased GLS, larger IS as well as presence of MVO, indicating plasma NPY as a novel clinical risk marker post STEMI.
View article: Culprit Lesion Vessel Size and Risk of Reperfusion Injury in ST‐Segment Elevation Myocardial Infarction: A Cardiac Magnetic Resonance Imaging Study
Culprit Lesion Vessel Size and Risk of Reperfusion Injury in ST‐Segment Elevation Myocardial Infarction: A Cardiac Magnetic Resonance Imaging Study Open
Background Microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH) are well‐established imaging biomarkers of failed myocardial tissue reperfusion in patients with ST‐segment elevation–myocardial infarction treated with percut…
View article: Association of dysglycaemia with persistent infarct core iron in patients with acute ST-segment elevation myocardial infarction
Association of dysglycaemia with persistent infarct core iron in patients with acute ST-segment elevation myocardial infarction Open
In STEMI patients treated with primary PCI, ongoing dysglycaemia defined by HbA1c is independently associated with persistent infarct core iron and a lower likelihood of iron resolution. These findings suggest a potential association betwe…
View article: Association of dysglycaemia with persistent infarct core iron in patients with acute ST-segment elevation myocardial infarction
Association of dysglycaemia with persistent infarct core iron in patients with acute ST-segment elevation myocardial infarction Open
Background Dysglycaemia increases the risk of myocardial infarction and subsequent recurrent cardiovascular events. However, the role of dysglycaemia in ischemia/reperfusion injury with development of irreversible myocardial tissue alterat…
View article: Time of day dependent symptom onset is not associated with left ventricular function and myocardial damage after ST-segment elevation myocardial infarction
Time of day dependent symptom onset is not associated with left ventricular function and myocardial damage after ST-segment elevation myocardial infarction Open
Background Circadian processes are suggested to influence ischemic injury in ST-segment elevation myocardial infarction (STEMI). Observational data suspect a circadian dependence of the occurrence of microvascular obstruction (MVO) in pati…
View article: E-wave propagation index as a marker for left ventricular thrombi post-ST elevation myocardial infarction
E-wave propagation index as a marker for left ventricular thrombi post-ST elevation myocardial infarction Open
Background The E-wave propagation index (EPI) is a novel echocardiographic measure for quantifying apical washout in the left ventricle (LV) and thus a promising marker of an elevated risk for LV thrombus. The association between EPI and L…
View article: Improved detection of echocardiographically occult left ventricular thrombi following ST-elevation myocardial infarction
Improved detection of echocardiographically occult left ventricular thrombi following ST-elevation myocardial infarction Open
Background and Aims Patients with STEMI are at significant risk for developing left ventricular thrombi (LVT). However, this complication often (up to 65%) remains undetected by using transthoracic echocardiography (TTE), referred to as TT…
View article: Takotsubo syndrome before and during the COVID‐19 pandemic in Austria: a retrospective cohort study (TOSCA‐19)
Takotsubo syndrome before and during the COVID‐19 pandemic in Austria: a retrospective cohort study (TOSCA‐19) Open
Aims This study aims to investigate the prevalence of Takotsubo syndrome (TTS) as a percentage of the total number of acute coronary syndrome (ACS), including non‐STE‐elevation myocardial infarction and ST‐elevation myocardial infarction, …
View article: Temporal Trends in Infarct Severity Outcomes in ST‐Segment–Elevation Myocardial Infarction: A Cardiac Magnetic Resonance Imaging Study
Temporal Trends in Infarct Severity Outcomes in ST‐Segment–Elevation Myocardial Infarction: A Cardiac Magnetic Resonance Imaging Study Open
Background Severity of myocardial tissue injury is a main determinant of morbidity and death related to ST‐segment–elevation myocardial infarction (STEMI). Temporal trends of infarct characteristics at the myocardial tissue level have not …
View article: Mitral Annular Disjunction in Out-of-Hospital Cardiac Arrest Patients – a Retrospective Cardiac MRI Study
Mitral Annular Disjunction in Out-of-Hospital Cardiac Arrest Patients – a Retrospective Cardiac MRI Study Open
Background Mitral annular disjunction (MAD), defined as defective attachment of the mitral annulus to the ventricular myocardium, has recently been linked to malignant arrhythmias. However, its role and prognostic significance in patients …
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View article: Temporal trends and outcomes in ST-segment elevation myocardial infarction: a cardiac magnetic resonance imaging study over the course of 15 years
Temporal trends and outcomes in ST-segment elevation myocardial infarction: a cardiac magnetic resonance imaging study over the course of 15 years Open
Aims Development of evidence-based treatments in ST-elevation myocardial infarction (STEMI) patients during the last 30 years have been associated with improved outcome; however, there are data suggesting a plateauing since around 2008 (1)…
View article: Prognostic significance of left ventricular functional parameters in relation to infarct location after ST-elevation myocardial infarction
Prognostic significance of left ventricular functional parameters in relation to infarct location after ST-elevation myocardial infarction Open
Aims In survivors of ST-elevation myocardial infarction (STEMI), the impact of infarct location on the prognostic significance of left ventricular functional parameters is not well established. The aim of this study was to investigate the …
View article: Association between inflammation and left ventricular thrombus formation following ST-elevation myocardial infarction
Association between inflammation and left ventricular thrombus formation following ST-elevation myocardial infarction Open
Background Current evidence suggests a link between the inflammatory state and left ventricular thrombus (LVT) formation following ST-elevation myocardial infarction (STEMI). However, a comprehensive study investigating the association bet…
View article: Cardiac magnetic resonance imaging versus computed tomography to guide transcatheter aortic valve replacement: study protocol for a randomized trial (TAVR-CMR)
Cardiac magnetic resonance imaging versus computed tomography to guide transcatheter aortic valve replacement: study protocol for a randomized trial (TAVR-CMR) Open
View article: Prognostic value of pulmonary transit time by cardiac magnetic resonance imaging in ST-elevation myocardial infarction
Prognostic value of pulmonary transit time by cardiac magnetic resonance imaging in ST-elevation myocardial infarction Open
View article: Neutrophile-Lymphocyte Ratio and Outcome in Takotsubo Syndrome
Neutrophile-Lymphocyte Ratio and Outcome in Takotsubo Syndrome Open
Background: Takotsubo syndrome (TTS) is an important type of acute heart failure with significant risk of acute complications and death. In this analysis we sought to identify predictors for in-hospital clinical outcome in TTS patients and…
View article: Cardiac Magnetic Resonance Imaging versus Computed Tomography to Guide Transcatheter Aortic Valve Replacement: Study Protocol for a Randomized Trial (TAVR-CMR)
Cardiac Magnetic Resonance Imaging versus Computed Tomography to Guide Transcatheter Aortic Valve Replacement: Study Protocol for a Randomized Trial (TAVR-CMR) Open
Background The standard procedure for the planning of transcatheter aortic valve replacement (TAVR) is the combination of echocardiography, coronary angiography and cardiovascular computed tomography (TAVR-CT) for the exact determination o…
View article: A novel approach to determine aortic valve area with phase-contrast cardiovascular magnetic resonance
A novel approach to determine aortic valve area with phase-contrast cardiovascular magnetic resonance Open
View article: Cardiac injury after COVID-19: Primary cardiac and primary non-cardiac etiology makes a difference
Cardiac injury after COVID-19: Primary cardiac and primary non-cardiac etiology makes a difference Open
View article: Association of C-Reactive Protein Velocity with Early Left Ventricular Dysfunction in Patients with First ST-Elevation Myocardial Infarction
Association of C-Reactive Protein Velocity with Early Left Ventricular Dysfunction in Patients with First ST-Elevation Myocardial Infarction Open
C-reactive protein velocity (CRPv) has been proposed as a very early and sensitive risk predictor in patients with ST-elevation myocardial infarction (STEMI). However, the association of CRPv with early left ventricular (LV) dysfunction af…
View article: Association of plasma interleukin-6 with infarct size, reperfusion injury, and adverse remodelling after ST-elevation myocardial infarction
Association of plasma interleukin-6 with infarct size, reperfusion injury, and adverse remodelling after ST-elevation myocardial infarction Open
Aims Little is known about the clinical relevance of interleukin (IL)-6 in patients with acute ST-elevation myocardial infarction (STEMI). This study examined the possible associations of plasma IL-6 concentrations with infarct size (IS), …