Ivan Taietti
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View article: Italian pediatric experts' consensus statement on diagnosis and management of primary atopic disorders
Italian pediatric experts' consensus statement on diagnosis and management of primary atopic disorders Open
Background Primary Atopic Disorders (PAD) represent a recently recognized subset of inborn errors of immunity (IEI), characterized by severe atopy driven by genetic mutations leading to dysregulated type 2 immune responses, excessive mast …
View article: Application of Artificial Intelligence in Inborn Errors of Immunity Identification and Management: Past, Present, and Future—A Systematic Review
Application of Artificial Intelligence in Inborn Errors of Immunity Identification and Management: Past, Present, and Future—A Systematic Review Open
Background: Inborn errors of immunity (IEI) are mainly genetically driven disorders that affect immune function and present with highly heterogeneous clinical manifestations, ranging from severe combined immunodeficiency (SCID) to adult-on…
View article: Clinical Heterogeneity of Early-Onset Autoimmune Gastritis: From the Evidence to a Pediatric Tailored Algorithm
Clinical Heterogeneity of Early-Onset Autoimmune Gastritis: From the Evidence to a Pediatric Tailored Algorithm Open
Autoimmune gastritis (AIG) is an uncommon and often underestimated condition in children, characterized by chronic stomach inflammation leading to the destruction of oxyntic glands with subsequent atrophic and metaplastic changes. This con…
View article: Inborn errors of immunity with atopic phenotypes in the allergy and immunology clinic: a practical review
Inborn errors of immunity with atopic phenotypes in the allergy and immunology clinic: a practical review Open
Purpose of review Inborn errors of immunity with atopic phenotypes (IEIwA) are a subgroup of IEI that may present with severe and/or multiple atopic clinical manifestations. Because of their specific clinical management and prognosis, it i…
View article: Avascular necrosis in pediatric rheumatic diseases: an Italian retrospective multicentre study
Avascular necrosis in pediatric rheumatic diseases: an Italian retrospective multicentre study Open
Background Atraumatic avascular necrosis (AVN) is a severe condition that may complicate the course of rheumatic diseases and contribute to long-term damage. However, there is a lack of evidence on this rare event in pediatric rheumatology…
View article: Expanding the Spectrum of Autosomal Dominant ATP6V1A-Related Disease: Case Report and Literature Review
Expanding the Spectrum of Autosomal Dominant ATP6V1A-Related Disease: Case Report and Literature Review Open
Background: Developmental and epileptic encephalopathies (DEE) are a group of disorders often linked to de novo mutations, including those in the ATP6V1A gene. These mutations, particularly dominant gain-of-function (GOF) variants, have be…
View article: Invasive Streptococcal Infection in Children: An Italian Case Series
Invasive Streptococcal Infection in Children: An Italian Case Series Open
Since October 2022, alerts have spread from several countries about the increase in invasive group A streptococcal (iGAS) and scarlet fever cases affecting young children. We aim to analyze the epidemiology of GAS infections in the last 12…
View article: Editorial comment on the Special Issue “Omics in Food Allergy”
Editorial comment on the Special Issue “Omics in Food Allergy” Open
Editorial comment on the Special Issue "Omics in Food Allergy"Riccardo Castagnoli1,2, Ivan Taietti1,2,*, Agnes Sze-Yin Leung3, Philippe Eigenmann41. Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, Univ…
View article: Selective IgM Deficiency: Evidence, Controversies, and Gaps
Selective IgM Deficiency: Evidence, Controversies, and Gaps Open
Selective Immunoglobulin M deficiency (SIgMD) has been recently included in the inborn errors of immunity (IEI) classification by the International Union of Immunological Societies Expert Committee. The understanding of SIgMD is still extr…
View article: Clinical and immunological phenotypes of selective <scp>IgM</scp> deficiency in children: Results from a multicenter study
Clinical and immunological phenotypes of selective <span>IgM</span> deficiency in children: Results from a multicenter study Open
Background A few studies assessed the clinical and immunological features of selective IgM deficiency (SIgMD), especially in the pediatric age. We aimed to characterize the clinical and immunological phenotypes of a cohort of pediatric pat…
View article: Prognostic impact of achieving LDL cholesterol guidelines-recommended target in secondary prevention: a real-world study
Prognostic impact of achieving LDL cholesterol guidelines-recommended target in secondary prevention: a real-world study Open
Background Lipid management plays a key role in secondary prevention after acute coronary syndrome. The 2019 European Society of Cardiology guidelines recommend a more ambitious target than the previous guidelines version (i.e., to achieve…
View article: 386 Achieving Ldl Cholesterol Target In A Real-World Secondary Prevention Cohort: When Two Is Better Than One
386 Achieving Ldl Cholesterol Target In A Real-World Secondary Prevention Cohort: When Two Is Better Than One Open
Aims Lipid management plays a key role in secondary prevention after acute coronary syndrome. Current European Society of Cardiology guidelines recommend a dual goal: to achieve LDL cholesterol (LDL-C) <55 mg/dL, and to reduce it ≥ 50% …