Ivana Ćelap
YOU?
Author Swipe
View article: Circulating microRNAs in prostate cancer — Non-invasive biomarkers for diagnosis, prognosis and therapy: A review
Circulating microRNAs in prostate cancer — Non-invasive biomarkers for diagnosis, prognosis and therapy: A review Open
Prostate cancer (PC) is a common malignancy driven by interacting genetic, environmental, and lifestyle factors, including hereditary mutations (BRCA1/2, HPC1, AR variants), premalignant lesions [proliferative inflammatory atrophy (PIA), p…
View article: Serum Diamine Oxidase Levels in Relation to Skin Prick Testing and Specific IgE in Adults with Self-Reported Food Allergy
Serum Diamine Oxidase Levels in Relation to Skin Prick Testing and Specific IgE in Adults with Self-Reported Food Allergy Open
Background: Self-reported food allergy is a common concern among adults and often prompts the use of diagnostic allergy testing. However, serum diamine oxidase (DAO) measurement is rarely performed, despite the fact that symptoms of histam…
View article: ‘It does not end with delivery?’ Pregnancy-associated thrombotic microangiopathy in the setting of postpartum preeclampsia/eclampsia – case report
‘It does not end with delivery?’ Pregnancy-associated thrombotic microangiopathy in the setting of postpartum preeclampsia/eclampsia – case report Open
this case is an example of pregnancy-associated TMA in the setting of preeclampsia in postpartum period which progressed to eclampsia due to the uncontrolled arterial hypertension. Upon vigorous blood pressure management, signs of TMA full…
View article: Salivary Cortisol Concentration Is an Objective Measure of the Physiological Response to Loud Music
Salivary Cortisol Concentration Is an Objective Measure of the Physiological Response to Loud Music Open
Purpose: This study examines the potential associations between salivary cortisol concentrations and subjective stress test scores in healthy individuals subjected to sound-related, psychological, and physical stressors. Methods: This stud…
View article: Complete blood count parameters and inflammation-related biomarkers in patients with colorectal carcinoma
Complete blood count parameters and inflammation-related biomarkers in patients with colorectal carcinoma Open
The aim of this study was to determine whether there are differences in complete blood count parameters (CBC) and inflammation-related biomarkers, MPV/PC, PLR, NLR, LWR, LMR, NMR, and LCR, among patients with colorectal carcinoma (CRC) and…
View article: MicroRNA-193a-3p as a Valuable Biomarker for Discriminating between Colorectal Cancer and Colorectal Adenoma Patients
MicroRNA-193a-3p as a Valuable Biomarker for Discriminating between Colorectal Cancer and Colorectal Adenoma Patients Open
Specific markers for colorectal cancer (CRC), preceded by colorectal adenoma (pre-CRC), are lacking. This study aimed to investigate whether microRNAs (miR-19a-3p, miR-92a-3p, miR-193a-3p, and miR-210-3p) from tissues and exosomes are pote…
View article: Algorithm for Rapid Exclusion of Clinically Relevant Plasma Levels of Direct Oral Anticoagulants in Patients Using the DOAC Dipstick: An Expert Consensus Paper
Algorithm for Rapid Exclusion of Clinically Relevant Plasma Levels of Direct Oral Anticoagulants in Patients Using the DOAC Dipstick: An Expert Consensus Paper Open
With the widespread use of direct oral anticoagulants (DOACs), there is an urgent need for a rapid assay to exclude clinically relevant plasma levels. Accurate and rapid determination of DOAC levels would guide medical decision-making to (…
View article: Glucose inhibitor tubes in Croatian laboratories: are we doing well?
Glucose inhibitor tubes in Croatian laboratories: are we doing well? Open
Laboratories in Croatia do not follow the recommended procedures regarding glycolysis inhibitors for glucose determination.
View article: CCL20 chemokine and other proinflammatory markers after Ad26.COV2.S vaccination
CCL20 chemokine and other proinflammatory markers after Ad26.COV2.S vaccination Open
Although our results did not show changes in CCL20 concentration after the vaccination, possibly due to the study timeframe, further investigations on chemokine profile post SARS-CoV-2 immunization could facilitate the recognition of speci…
View article: Paraoxonase and arylesterase activity of paraoxonase 1 and oxidative stress parameters in cervical intraepithelial neoplasia
Paraoxonase and arylesterase activity of paraoxonase 1 and oxidative stress parameters in cervical intraepithelial neoplasia Open
IntroductionParaoxonase 1 (PON1) is the enzyme that removes carcinogenic radicals from lipids. The aim of the study was to investigate the differences in PON1 activity and oxidation stress parameters between patients with cervical intraepi…
View article: Corrigendum to: Post-treatment neutrophil to lymphocyte ratio as a prognostic tool in patients treated with tocilizumab for severe COVID-19 pneumonia - a single center experience
Corrigendum to: Post-treatment neutrophil to lymphocyte ratio as a prognostic tool in patients treated with tocilizumab for severe COVID-19 pneumonia - a single center experience Open
[This corrects the article DOI: 10.11613/BM.2023.020704.].
View article: PB1189 Concentrations of Direct Oral Anticoagulants Acting as FXa Inhibitors Could not be Accurately Determined in Patients Treated with Therapeutic Doses of Low Molecular Heparin as Bridging Therapy
PB1189 Concentrations of Direct Oral Anticoagulants Acting as FXa Inhibitors Could not be Accurately Determined in Patients Treated with Therapeutic Doses of Low Molecular Heparin as Bridging Therapy Open
View article: PB1173 Comparison of Rivaroxaban Concentrations Measured by Anti-Xa Rivaroxaban Calibrated Assay and LC-MS/MS
PB1173 Comparison of Rivaroxaban Concentrations Measured by Anti-Xa Rivaroxaban Calibrated Assay and LC-MS/MS Open
6-83) respectively (P = 0.442).Among all patients tested, 90 (3.3%) were LA positive, 205 (7.5%) were aCL positive (IgG 148, IgM 66 and IgG +IgM 9) and 108 (4.0%) were anti-β2GPI positive (IgG 78, IgM 47 and IgG +IgM 17).Single positivity …
View article: PB1178 Presentation of Four Real-Life Patients with Persistently Low Both Peak and Trough Direct Oral Anticoagulant Levels in Plasma: Potential Effect of Drug-Drug Interactions
PB1178 Presentation of Four Real-Life Patients with Persistently Low Both Peak and Trough Direct Oral Anticoagulant Levels in Plasma: Potential Effect of Drug-Drug Interactions Open
View article: PB1152 Reporting of DOAC Concentration as FXa Inhibitory Units - Potential Solution for Smaller Laboratories?
PB1152 Reporting of DOAC Concentration as FXa Inhibitory Units - Potential Solution for Smaller Laboratories? Open
Conclusion(s):Reflexive testing of positive LIA results using ELISA showed a reduction in false positive results compared to LIA alone (68% to 27.8%, respectively), a concordant reduction in the use of SRA, and demonstrated an improvement …
View article: PB1186 Combined DOAC and Antiplatelet Therapy Caused Menorrhagia in Young Woman -Case Report
PB1186 Combined DOAC and Antiplatelet Therapy Caused Menorrhagia in Young Woman -Case Report Open
significant difference observed between the in-house assay and the reference laboratory. Conclusion(s):The evaluated Anti-Xa LMWH reagent and instrument demonstrated comparable performance against the reference laboratory.The Stago instrum…
View article: PB1124 Peak Plasma Concentrations of Apixaban in Children, Adolescents and Young Adults with Different Dosing Regimens Applied
PB1124 Peak Plasma Concentrations of Apixaban in Children, Adolescents and Young Adults with Different Dosing Regimens Applied Open
Background: Low molecular weight peptide substrates allow the sensitive measurement of activated coagulation factor X (FXa) but may show deficits in selectivity.The addition of specific inhibitors increases the assay's selectivity but at t…
View article: PB0607 Evaluation of Proinflammatory and Haemostasis Markers after BNT162b2 SARS-CoV-2 Vaccination
PB0607 Evaluation of Proinflammatory and Haemostasis Markers after BNT162b2 SARS-CoV-2 Vaccination Open
View article: Changes in haemostasis and inflammatory markers after mRNA BNT162b2 and vector Ad26.CoV2.S SARS-CoV-2 vaccination
Changes in haemostasis and inflammatory markers after mRNA BNT162b2 and vector Ad26.CoV2.S SARS-CoV-2 vaccination Open
View article: Post-treatment neutrophil to lymphocyte ratio as a prognostic tool in patients treated with tocilizumab for severe COVID-19 pneumonia
Post-treatment neutrophil to lymphocyte ratio as a prognostic tool in patients treated with tocilizumab for severe COVID-19 pneumonia Open
IntroductionTocilizumab is used in patients with severe COVID-19 pneumonia and high concentration of IL-6. We studied potential prognostic role of neutrophil and lymphocyte count regarding tocilizumab treatment. Materials and methodsWe enr…
View article: Changes in Haemostasis and Inflammatory Markers after mRNA BNT162b2 and Vector Ad26.CoV2.S SARS-CoV-2 Vaccination
Changes in Haemostasis and Inflammatory Markers after mRNA BNT162b2 and Vector Ad26.CoV2.S SARS-CoV-2 Vaccination Open
View article: Circulating Tumor Cells in Colorectal Cancer: Detection Systems and Clinical Utility
Circulating Tumor Cells in Colorectal Cancer: Detection Systems and Clinical Utility Open
Colorectal cancer (CRC) is the third most common cancer worldwide. The high mortality from CRC is mainly related to metastasis affecting distant organs and their function. Dissemination of tumor cells from the primary tumor and hematogeneo…
View article: Direct oral anticoagulants (DOACs): From the laboratory point of view
Direct oral anticoagulants (DOACs): From the laboratory point of view Open
Direct oral anticoagulants (DOACs) represent a new generation of drugs that have been increasingly used in the prevention and treatment of thromboembolic states. According to the mechanism of anticoagulant action, DOACs are divided into tw…
View article: DOAC Dipstick Testing Can Reliably Exclude the Presence of Clinically Relevant DOAC Concentrations in Circulation
DOAC Dipstick Testing Can Reliably Exclude the Presence of Clinically Relevant DOAC Concentrations in Circulation Open
In certain clinical situations, it is necessary to determine whether clinically relevant plasma levels of direct oral anticoagulants (DOACs) are present. We examined whether qualitative testing of DOACs in urine samples can exclude DOAC pl…
View article: Verification policies in Croatian medical biochemistry laboratories: a survey of the practice
Verification policies in Croatian medical biochemistry laboratories: a survey of the practice Open
The aim of this study was to screen practices used in verification procedures for methods/analysers among medical biochemistry laboratories (MBLs) in Croatia. We hypothesized that these procedures differ widely from laboratory to laborator…
View article: Profiling Colorectal Cancer in the Landscape Personalized Testing—Advantages of Liquid Biopsy
Profiling Colorectal Cancer in the Landscape Personalized Testing—Advantages of Liquid Biopsy Open
Drug-specific therapeutic approaches for colorectal cancer (CRC) have contributed to significant improvements in patient health. Nevertheless, there is still a great need to improve the personalization of treatments based on genetic and ep…
View article: Comparison of diagnostic accuracy for eight SARS-CoV-2 serological assays
Comparison of diagnostic accuracy for eight SARS-CoV-2 serological assays Open
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological tests have been suggested as an additional diagnostic tool in highly suspected cases with a negative molecular test and determination of seroprevalence …
View article: Impact of thrombus aspiration on the activity of plasminogen activator inhibitor‑1 during acute ST-segment elevation myocardial infarction
Impact of thrombus aspiration on the activity of plasminogen activator inhibitor‑1 during acute ST-segment elevation myocardial infarction Open
Thrombus aspiration and PAI-1 1281 disease established within the first 24 hours, active malignant disease and chronic hepatic failure requiring treatment.All patients were participants of the scientific project funded by the Croatian Mini…
View article: Sodium-glucose cotransporter 2 inhibitors’ mechanisms of action in heart failure
Sodium-glucose cotransporter 2 inhibitors’ mechanisms of action in heart failure Open
Three major cardiovascular outcome trials (CVOTs) with a new class of antidiabetic drugs - sodium-glucose cotransporter 2 (SGLT2) inhibitors (EMPA-REG OUTCOME trial with empagliflozin, CANVAS Program with canagliflozin, DECLARE-TIMI 58 wit…
View article: Analytical verification and comparison of chromogenic assays for dabigatran, rivaroxaban and apixaban determination on BCSXP and STA Compact Max analysers
Analytical verification and comparison of chromogenic assays for dabigatran, rivaroxaban and apixaban determination on BCSXP and STA Compact Max analysers Open
Introduction: The aim of the study was to perform analytical verification and comparison of chromogenic assays for determination of dabigatran, rivaroxaban and apixaban concentration on BCSXP and STA Compact Max analysers. Materials and me…