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View article: Accuracy assessment of a micro-Raman spectroscopy method for small microplastic particles in infant milk formula
Accuracy assessment of a micro-Raman spectroscopy method for small microplastic particles in infant milk formula Open
The presence of microplastics (MPs) in the food chain is increasingly documented, raising concerns over potential risks to human health. Despite growing efforts, standardized methods for MPs detection in food matrices remain limited. This …
View article: A machine learning tool to analyze spectroscopic changes in high-dimensional data
A machine learning tool to analyze spectroscopic changes in high-dimensional data Open
When nanoparticles (NPs) are introduced into a biological solution, layers of biomolecules form on their surface, creating a corona. Understanding how the protein's structure evolves into the corona is essential for evaluating the safety a…
View article: Pulmonary hazards of nanoplastic particles: a study using polystyrene in in vitro models of the alveolar and bronchial epithelium
Pulmonary hazards of nanoplastic particles: a study using polystyrene in in vitro models of the alveolar and bronchial epithelium Open
View article: Enhancing the translational potential of photo-responsive covellite in medicine: solvent-free tuning of CuS nanoparticles LSPR and control of their stability in aqueous media by a carbonaceous shell
Enhancing the translational potential of photo-responsive covellite in medicine: solvent-free tuning of CuS nanoparticles LSPR and control of their stability in aqueous media by a carbonaceous shell Open
View article: A Machine Learning Tool to Analyse Spectroscopic Changes in High-Dimensional Data
A Machine Learning Tool to Analyse Spectroscopic Changes in High-Dimensional Data Open
When nanoparticles (NPs) are introduced into a biological solution, layers of biomolecules form on their surface, creating a corona. Understanding how the structure of the protein evolves into the corona is essential for evaluating the saf…
View article: Assessing gut barrier integrity and reproductive performance following pre-mating oral administration of solid-lipid-nanoparticles designed for drug delivery
Assessing gut barrier integrity and reproductive performance following pre-mating oral administration of solid-lipid-nanoparticles designed for drug delivery Open
Solid lipid nanoparticles (SLNs) have gained interest as drug delivery carriers due to their efficient cellular internalization and increased therapeutic effect of the loaded drug, with minimal side effects. Although recently several studi…
View article: Carbon Nanoparticle-Loaded PLA Nanofibers via Electrospinning for Food Packaging
Carbon Nanoparticle-Loaded PLA Nanofibers via Electrospinning for Food Packaging Open
The development of nanocomposite materials for food packaging applications requires a precise balance of material functionality, safety, and regulatory compliance. In this work, the design, manufacturing, optimization, feasibility, and saf…
View article: Uncovering Hidden Microbial Ligands in Micro- and Nanoplastics Highlights a Need to Screen Beyond Endotoxins
Uncovering Hidden Microbial Ligands in Micro- and Nanoplastics Highlights a Need to Screen Beyond Endotoxins Open
View article: Hydrothermal carbonization synthesis of amorphous carbon nanoparticles (15–150 nm) with fine-tuning of the size, bulk order, and the consequent impact on antioxidant and photothermal properties
Hydrothermal carbonization synthesis of amorphous carbon nanoparticles (15–150 nm) with fine-tuning of the size, bulk order, and the consequent impact on antioxidant and photothermal properties Open
Parameter modification and post-synthesis hydrothermal process were applied to tune the size and increase bulk order of CNP, resulting in increased photothermal and antioxidant activities, without affecting the morphological and colloidal …
View article: <i>In chemico</i> categorization of magnetite-, hydroxyapatite-, and Ag-derived hybrid nanobiomaterials based on the surface oxidative reactivity: implications of doping and coating
<i>In chemico</i> categorization of magnetite-, hydroxyapatite-, and Ag-derived hybrid nanobiomaterials based on the surface oxidative reactivity: implications of doping and coating Open
Dopants and coatings regulate the redox profile of magnetite-, Ag-, and HA-hybrid NBMs. Created in BioRender. Alcolea-Rodriguez, V. (2025) https://BioRender.com/fm1uwvb.
View article: Molecular insights into the interaction between cytochrome c and carbon nanomaterials
Molecular insights into the interaction between cytochrome c and carbon nanomaterials Open
Carbon nanomaterials (CNMs) are a heterogeneous class of advanced materials. Their widespread use is associated with human safety concerns, which can be addressed by safe-by design strategies. This implies a deep knowledge of how physico-c…
View article: Assessing the inhaled dose of nanomaterials by nanoparticle tracking analysis (NTA) of exhaled breath condensate (EBC) and its relationship with lung inflammatory biomarkers
Assessing the inhaled dose of nanomaterials by nanoparticle tracking analysis (NTA) of exhaled breath condensate (EBC) and its relationship with lung inflammatory biomarkers Open
The widespread and increasing use of nanomaterials has resulted in a higher likelihood of exposure by inhalation for nanotechnology workers. However, tracking the internal dose of nanoparticles deposited at the airways level, is still chal…
View article: Molecular Mechanisms Driving Carbon Nanoparticles-Induced Nadh-Independent Cytochrome C Reduction, Unfolding and Peroxidase Activity Inhibition
Molecular Mechanisms Driving Carbon Nanoparticles-Induced Nadh-Independent Cytochrome C Reduction, Unfolding and Peroxidase Activity Inhibition Open
View article: Understanding the role of biomolecular coronas in human exposure to nanomaterials
Understanding the role of biomolecular coronas in human exposure to nanomaterials Open
The distinct molecules composing the biological fluids lead to different coronas on NMs, altering their physicochemical properties and affect their biological fate.
View article: Advanced materials - Food grade melatonin-loaded Lipid Surfactant Submicron Particles (LSSP)–environmental impacts
Advanced materials - Food grade melatonin-loaded Lipid Surfactant Submicron Particles (LSSP)–environmental impacts Open
Lipid-based nanoparticles (LNPs) are advanced materials (AdMa), particularly relevant for drug delivery of poorly water-soluble compounds, while also providing protection, stabilization, and controlled release of the drugs/active substance…
View article: A New Paclitaxel Formulation Based on Secretome Isolated from Mesenchymal Stem Cells Shows a Significant Cytotoxic Effect on Osteosarcoma Cell Lines
A New Paclitaxel Formulation Based on Secretome Isolated from Mesenchymal Stem Cells Shows a Significant Cytotoxic Effect on Osteosarcoma Cell Lines Open
Background: Osteosarcoma (OS) represents a rare cancer with an unfavorable prognosis that needs innovative treatment. The aim was to isolate a secretome from mesenchymal stem cells (MSCs) that are treated with paclitaxel (PTX)-containing m…
View article: Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay
Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay Open
Toxicity evaluation of engineered nanomaterials is challenging due to the ever increasing number of materials and because nanomaterials (NMs) frequently interfere with commonly used assays. Hence, there is a need for robust, high-throughpu…
View article: Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay - data from the article published in PlosOne
Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay - data from the article published in PlosOne Open
Data that have been used in the manuscript "Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay" by M. Fontaine et al., published in PlosOne in 2023.
View article: Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay - data from the article published in PlosOne
Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay - data from the article published in PlosOne Open
Data that have been used in the manuscript "Nanomaterial genotoxicity evaluation using the high-throughput p53-binding protein 1 (53BP1) assay" by M. Fontaine et al., published in PlosOne in 2023.
View article: Biomineralization: A new tool for developing eco-sustainable Ti-doped hydroxyapatite-based hybrid UV filters
Biomineralization: A new tool for developing eco-sustainable Ti-doped hydroxyapatite-based hybrid UV filters Open
It is well known that the prolonged exposure to UV radiation from sunlight can compromise human health and is particularly damaging to the skin, leading to sunburn, photo-aging and skin cancer. Sunscreen formulations containing UV-filters …
View article: Nanoparticle concentration in Exhaled Breath Condensate as a novel biomarker for assessing exposure to nanomaterials in occupational environment
Nanoparticle concentration in Exhaled Breath Condensate as a novel biomarker for assessing exposure to nanomaterials in occupational environment Open
Population Medicine considers the following types of articles:• Research Papers -reports of data from original research or secondary dataset analyses.• Review Papers -comprehensive, authoritative, reviews within the journal's scope.These i…
View article: Photoresponsive Inorganic Nanomaterials in Oncology
Photoresponsive Inorganic Nanomaterials in Oncology Open
The diagnosis and treatment of cancer are continuously evolving in search of more efficient, safe, and personalized approaches. Therapies based on nanoparticles or physical stimuli-responsive substances have shown great potential to overco…
View article: Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and fate in humans
Nano- and microplastics: a comprehensive review on their exposure routes, translocation, and fate in humans Open
View article: Inhibitory Effect against Listeria monocytogenes of Carbon Nanoparticles Loaded with Copper as Precursors of Food Active Packaging
Inhibitory Effect against Listeria monocytogenes of Carbon Nanoparticles Loaded with Copper as Precursors of Food Active Packaging Open
Human listeriosis is a serious foodborne disease of which outbreaks are occurring increasingly frequently in Europe. Around the world, different legal requirements exist to guarantee food safety. Nanomaterials are increasingly used in the …
View article: Changes of physico-chemical properties of nano-biomaterials by digestion fluids affect the physiological properties of epithelial intestinal cells and barrier models
Changes of physico-chemical properties of nano-biomaterials by digestion fluids affect the physiological properties of epithelial intestinal cells and barrier models Open
Background The widespread use of nano-biomaterials (NBMs) has increased the chance of human exposure. Although ingestion is one of the major routes of exposure to NBMs, it is not thoroughly studied to date. NBMs are expected to be dramatic…
View article: Molecular Aspects of the Interaction with Gram-Negative and Gram-Positive Bacteria of Hydrothermal Carbon Nanoparticles Associated with Bac8c<sup>2,5Leu</sup> Antimicrobial Peptide
Molecular Aspects of the Interaction with Gram-Negative and Gram-Positive Bacteria of Hydrothermal Carbon Nanoparticles Associated with Bac8c<sup>2,5Leu</sup> Antimicrobial Peptide Open
Antimicrobial peptides (AMPs) are widely studied as therapeutic agents due to their broad-spectrum efficacy against infections. However, their clinical use is hampered by the low in vivo bioavailability and systemic toxicity. Such limitati…
View article: A Biomonitoring Pilot Study in Workers from a Paints Production Plant Exposed to Pigment-Grade Titanium Dioxide (TiO2)
A Biomonitoring Pilot Study in Workers from a Paints Production Plant Exposed to Pigment-Grade Titanium Dioxide (TiO2) Open
Among particulate matter composing paints, titanium dioxide (TiO2) forms about 20% of the final suspension. Although TiO2 is broadly used in many applications, TiO2 powders represent an established respiratory hazard for workers with long-…
View article: Biological interactions of ferromagnetic iron oxide–carbon nanohybrids with alveolar epithelial cells
Biological interactions of ferromagnetic iron oxide–carbon nanohybrids with alveolar epithelial cells Open
Iron oxide nanoparticles with a carbon shell (IONP@C) showed good colloidal stability in the biological environment, no cytotoxic effects and a peculiar intracellular trafficking pathway on a widely employed model of alveolar epithelial ce…
View article: Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate
Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate Open
View article: Efficacy, Biocompatibility and Degradability of Carbon Nanoparticles for Photothermal Therapy of Lung Cancer
Efficacy, Biocompatibility and Degradability of Carbon Nanoparticles for Photothermal Therapy of Lung Cancer Open
Aim: To investigate near infrared-induced phototoxicity toward lung cancer cells, and the biodegradability and effect on immune cells of glucose-derived carbon nanoparticles (CNPs). Methods: The human A549 lung adenocarcinoma…