Ivelina Yonova
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View article: Exploring the levels of variation, inequality and use of physical activity intervention referrals in England primary care from 2017–2020: a retrospective cohort study
Exploring the levels of variation, inequality and use of physical activity intervention referrals in England primary care from 2017–2020: a retrospective cohort study Open
Objectives In this study, we explore the use of physical activity intervention referrals in primary care in England and compare their use with the rate of cardiovascular disease (CVD) risk factors in England from 2017 to 2020. We also expl…
View article: Correction: Seasonal influenza: Modelling approaches to capture immunity propagation
Correction: Seasonal influenza: Modelling approaches to capture immunity propagation Open
[This corrects the article DOI: 10.1371/journal.pcbi.1007096.].
View article: Impact of General Practitioner Education on Acceptance of an Adjuvanted Seasonal Influenza Vaccine among Older Adults in England
Impact of General Practitioner Education on Acceptance of an Adjuvanted Seasonal Influenza Vaccine among Older Adults in England Open
Seasonal vaccination against influenza and in-pandemic COVID-19 vaccination are top public health priorities; vaccines are the primary means of reducing infections and also controlling pressures on health systems. During the 2018–2019 infl…
View article: An intercountry comparison of the impact of the paediatric live attenuated influenza vaccine (LAIV) programme across the UK and the Republic of Ireland (ROI), 2010 to 2017
An intercountry comparison of the impact of the paediatric live attenuated influenza vaccine (LAIV) programme across the UK and the Republic of Ireland (ROI), 2010 to 2017 Open
Background The universal paediatric live attenuated influenza vaccine (LAIV) programme commenced in the United Kingdom (UK) in 2013/2014. Since 2014/2015, all pre‐school and primary school children in Scotland and Northern Ireland have bee…
View article: A novel ontological approach reveals underuse and variation in the use of physical activity interventions to address CVD risk factors in England primary care: Observational study (Preprint)
A novel ontological approach reveals underuse and variation in the use of physical activity interventions to address CVD risk factors in England primary care: Observational study (Preprint) Open
BACKGROUND In 2019, cardiovascular disease (CVD) accounted for 14% of total disability-adjusted life years and 30% of all deaths in England. Fast forwarding to 2020, many healthcare systems were on the verge of being overwhelmed by COVID-…
View article: The Effect of the COVID-19 Pandemic on Glycemic Monitoring and Other Processes of Care for Type 2 Diabetes: Protocol for a Retrospective Cohort Study
The Effect of the COVID-19 Pandemic on Glycemic Monitoring and Other Processes of Care for Type 2 Diabetes: Protocol for a Retrospective Cohort Study Open
Background Social distancing and other nonpharmaceutical interventions to reduce the spread of COVID-19 infection in the United Kingdom have led to substantial changes in delivering ongoing care for patients with chronic conditions, includ…
View article: The Effect of the COVID-19 Pandemic on Glycemic Monitoring and Other Processes of Care for Type 2 Diabetes: Protocol for a Retrospective Cohort Study (Preprint)
The Effect of the COVID-19 Pandemic on Glycemic Monitoring and Other Processes of Care for Type 2 Diabetes: Protocol for a Retrospective Cohort Study (Preprint) Open
BACKGROUND Social distancing and other nonpharmaceutical interventions to reduce the spread of COVID-19 infection in the United Kingdom have led to substantial changes in delivering ongoing care for patients with chronic conditions, inclu…
View article: Household presentation of influenza and acute respiratory illnesses to a primary care sentinel network: retrospective database studies (2013–2018)
Household presentation of influenza and acute respiratory illnesses to a primary care sentinel network: retrospective database studies (2013–2018) Open
View article: Using an Ontology to Facilitate More Accurate Coding of Social Prescriptions Addressing Social Determinants of Health: Feasibility Study
Using an Ontology to Facilitate More Accurate Coding of Social Prescriptions Addressing Social Determinants of Health: Feasibility Study Open
Background National Health Service (NHS) England supports social prescribing in order to address social determinants of health, which account for approximately 80% of all health outcomes. Nevertheless, data on ongoing social prescribing ac…
View article: Optimising age coverage of seasonal influenza vaccination in England: A mathematical and health economic evaluation
Optimising age coverage of seasonal influenza vaccination in England: A mathematical and health economic evaluation Open
For infectious disease prevention, policy-makers are typically required to base policy decisions in light of operational and monetary restrictions, prohibiting implementation of all candidate interventions. To inform the evidence-base unde…
View article: Use and impact of social prescribing: a mixed-methods feasibility study protocol
Use and impact of social prescribing: a mixed-methods feasibility study protocol Open
Introduction Social prescribing aims to address social determinants of health, which account for 80%–90% of health outcomes, but the evidence base behind it is limited due to a lack of data linkingsocial prescribing activity and outcomes. …
View article: Using an Ontology to Facilitate More Accurate Coding of Social Prescriptions Addressing Social Determinants of Health: Feasibility Study (Preprint)
Using an Ontology to Facilitate More Accurate Coding of Social Prescriptions Addressing Social Determinants of Health: Feasibility Study (Preprint) Open
BACKGROUND National Health Service (NHS) England supports social prescribing in order to address social determinants of health, which account for approximately 80% of all health outcomes. Nevertheless, data on ongoing social prescribing a…
View article: CASNET2: evaluation of an electronic safety netting cancer toolkit for the primary care electronic health record: protocol for a pragmatic stepped-wedge RCT
CASNET2: evaluation of an electronic safety netting cancer toolkit for the primary care electronic health record: protocol for a pragmatic stepped-wedge RCT Open
Introduction Safety-netting in primary care is the best practice in cancer diagnosis, ensuring that patients are followed up until symptoms are explained or have resolved. Currently, clinicians use haphazard manual solutions. The ubiquitou…
View article: Integrating molecular point-of-care testing for influenza into primary care: a mixed-methods feasibility study
Integrating molecular point-of-care testing for influenza into primary care: a mixed-methods feasibility study Open
Background Molecular point-of-care testing (POCT) for influenza in primary care could influence clinical care and patient outcomes. Aim To assess the feasibility of incorporating influenza POCT into general practice in England. Design and …
View article: Impact of the herpes zoster vaccination programme on hospitalised and general practice consulted herpes zoster in the 5 years after its introduction in England: a population-based study
Impact of the herpes zoster vaccination programme on hospitalised and general practice consulted herpes zoster in the 5 years after its introduction in England: a population-based study Open
Objectives To assess the impact of herpes zoster vaccination in the 5 years after introduction for 70- to 79-year-olds in England in September 2013. Design Population based ecological impact assessment. Setting Hospitals covering the whole…
View article: Optimising age coverage of seasonal influenza vaccination in England: A mathematical and health economic evaluation
Optimising age coverage of seasonal influenza vaccination in England: A mathematical and health economic evaluation Open
For infectious disease prevention, policy-makers are typically required to base policy decisions in light of operational and monetary restrictions, prohibiting implementation of all candidate interventions. To inform the evidence-base unde…
View article: Brand-specific enhanced safety surveillance of GSK’s Fluarix Tetra seasonal influenza vaccine in England: 2017/2018 season
Brand-specific enhanced safety surveillance of GSK’s Fluarix Tetra seasonal influenza vaccine in England: 2017/2018 season Open
In compliance with the European Medicine Agency guidance to detect any potential safety concerns associated with influenza vaccination, an enhanced safety surveillance study was conducted in England during the 2017/18 influenza season. The…
View article: Additional file 1 of Household presentation of influenza and acute respiratory illnesses to a primary care sentinel network: retrospective database studies (2013–2018)
Additional file 1 of Household presentation of influenza and acute respiratory illnesses to a primary care sentinel network: retrospective database studies (2013–2018) Open
Additional file 1.
View article: Feasibility of Point-of-Care Testing for Influenza Within a National Primary Care Sentinel Surveillance Network in England: Protocol for a Mixed Methods Study
Feasibility of Point-of-Care Testing for Influenza Within a National Primary Care Sentinel Surveillance Network in England: Protocol for a Mixed Methods Study Open
Background Point-of-care testing (POCT) for influenza promises to provide real-time information to influence clinical decision making and improve patient outcomes. Public Health England has published a toolkit to assist implementation of t…
View article: Enhanced safety surveillance of influenza vaccines in general practice, winter 2015-16: Feasibility study
Enhanced safety surveillance of influenza vaccines in general practice, winter 2015-16: Feasibility study Open
BACKGROUND:The European Medicines Agency (EMA) requires vaccine manufacturers to conduct enhanced real-time surveillance of seasonal influenza vaccination. The EMA has specified a list of adverse events of interest to be monitored. The EMA…
View article: Seasonal influenza: Modelling approaches to capture immunity propagation
Seasonal influenza: Modelling approaches to capture immunity propagation Open
Seasonal influenza poses serious problems for global public health, being a significant contributor to morbidity and mortality. In England, there has been a long-standing national vaccination programme, with vaccination of at-risk groups a…
View article: Analysis of Primary Care Computerized Medical Records (CMR) Data With Deep Autoencoders (DAE)
Analysis of Primary Care Computerized Medical Records (CMR) Data With Deep Autoencoders (DAE) Open
The use of deep learning is becoming increasingly important in the analysis of medical data such as pattern recognition for classification. The use of primary healthcare computational medical records (CMR) data is vital in prediction of in…
View article: End of season influenza vaccine effectiveness in adults and children in the United Kingdom in 2017/18
End of season influenza vaccine effectiveness in adults and children in the United Kingdom in 2017/18 Open
Background In the United Kingdom (UK), in recent influenza seasons, children are offered a quadrivalent live attenuated influenza vaccine (LAIV4), and eligible adults mainly trivalent inactivated vaccine (TIV). Aim To estimate the UK end-o…
View article: Seasonal influenza: Modelling approaches to capture immunity propagation
Seasonal influenza: Modelling approaches to capture immunity propagation Open
Seasonal influenza poses serious problems for global public health, being a significant contributor to morbidity and mortality. In England, there has been a long-standing national vaccination programme, with vaccination of at-risk groups a…
View article: Feasibility of Point-of-Care Testing for Influenza Within a National Primary Care Sentinel Surveillance Network in England: Protocol for a Mixed Methods Study (Preprint)
Feasibility of Point-of-Care Testing for Influenza Within a National Primary Care Sentinel Surveillance Network in England: Protocol for a Mixed Methods Study (Preprint) Open
BACKGROUND Point-of-care testing (POCT) for influenza promises to provide real-time information to influence clinical decision making and improve patient outcomes. Public Health England has published a toolkit to assist implementation of …
View article: Enhanced Safety Surveillance of Influenza Vaccines in General Practice, Winter 2015-16: Feasibility Study
Enhanced Safety Surveillance of Influenza Vaccines in General Practice, Winter 2015-16: Feasibility Study Open
Background The European Medicines Agency (EMA) requires vaccine manufacturers to conduct enhanced real-time surveillance of seasonal influenza vaccination. The EMA has specified a list of adverse events of interest to be monitored. The EMA…
View article: Serological surveillance of influenza in an English sentinel network: pilot study protocol
Serological surveillance of influenza in an English sentinel network: pilot study protocol Open
Background Rapidly undertaken age-stratified serology studies can produce valuable data about a new emerging infection including background population immunity and seroincidence during an influenza pandemic. Traditionally seroepidemiology …
View article: Enhanced passive surveillance of influenza vaccination in England, 2016−2017– an observational study using an adverse events reporting card
Enhanced passive surveillance of influenza vaccination in England, 2016−2017– an observational study using an adverse events reporting card Open
Influenza is a major public health burden, mainly prevented by vaccination. Recommendations on influenza vaccine composition are updated annually and constant benefit-risk monitoring is therefore needed. We conducted near-real-time enhance…
View article: Feasibility of point-of-care testing for influenza within a national primary care sentinel surveillance network in England: Protocol for a mixed methods study
Feasibility of point-of-care testing for influenza within a national primary care sentinel surveillance network in England: Protocol for a mixed methods study Open
BACKGROUND: Point-of-care testing (POCT) for influenza promises to provide real-time information to influence clinical decision making and improve patient outcomes. Public Health England has published a toolkit to assist i…
View article: Uptake and effectiveness of influenza vaccine in those aged 65 years and older in the United Kingdom, influenza seasons 2010/11 to 2016/17
Uptake and effectiveness of influenza vaccine in those aged 65 years and older in the United Kingdom, influenza seasons 2010/11 to 2016/17 Open
Background In 2016/17, seasonal influenza vaccine was less effective in those aged 65 years and older in the United Kingdom. We describe the uptake, influenza-associated mortality and adjusted vaccine effectiveness (aVE) in this age group …