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View article: Optimization and preparation of in-situ mucoadhesive gel of azithromycin hydroxypropyl-β-cyclodextrin inclusion complex against upper respiratory tract infections
Optimization and preparation of in-situ mucoadhesive gel of azithromycin hydroxypropyl-β-cyclodextrin inclusion complex against upper respiratory tract infections Open
The developed mucoadhesive in situ gels demonstrated promising in vivo performance, primarily due to their effective antimicrobial activity. In vivo, local retention studies confirmed that the formulations adhered to the throat mucosa and …
View article: In Silico and Therapeutic Efficacy of Glycyrrhizin‐Based Silver Nanoparticles Against Bacteria Related to Periodontitis
In Silico and Therapeutic Efficacy of Glycyrrhizin‐Based Silver Nanoparticles Against Bacteria Related to Periodontitis Open
Rising antibiotic resistance among periodontal pathogens poses a major challenge to treatment outcomes. This work investigates the possible combinatorial potential of AgNPs synthesized using glycyrrhizin, a natural biosurfactant, to combat…
View article: The Recent Development of Luteolin-loaded Nanocarrier in Targeting Cancer
The Recent Development of Luteolin-loaded Nanocarrier in Targeting Cancer Open
Introduction: Luteolin (LUT), a naturally occurring flavonoid found in vegetables, fruits, and herbal medicines, has been extensively studied for its pharmacological activities, including anti-proliferative and anticancer effects on variou…
View article: A doxorubicin loaded chitosan–poloxamer <i>in situ</i> implant for the treatment of breast cancer
A doxorubicin loaded chitosan–poloxamer <i>in situ</i> implant for the treatment of breast cancer Open
Doxorubicin-containing in situ gel made with chitosan (0.5% w/v) and poloxamer 407 (20% w/v) had a better biological and pharmacokinetic profile than the pure drug.