Song Iy Han
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Tubular adenoma with squamoid morules in colonic polyp: Cases report and literature review Open
Rationale: Squamoid morules (SM) are rare in colorectal adenomas. Submucosal pseudoinvasion in adenomas is similar to that in invasive carcinomas and needs to be differentiated, especially in the presence of mucin spillage. Patient concern…
Differentiation of inflammatory pseudotumors and malignant pulmonary nodules using the time-to-peak in first-pass dual-input volume computed tomography-perfusion Open
Compared with other perfusion parameters, TTP may be a more valuable parameter to differentiate IPTs from malignant SPNs.
Identifying nexilin as a central gene in neutrophil-driven abdominal aortic aneurysm pathogenesis Open
Objectives Abdominal aortic aneurysm (AAA) is an inflammation-driven disease in which neutrophil infiltration is critical to its progression. This study aims to explore the molecular mechanisms behind neutrophil infiltration in AAA and ide…
Hepatoprotective Effects of Aqueous Extract of Perilla fructescens against Alcohol-Induced Liver Injury in Mice Open
Excessive alcohol intake leads to significant physiological complications, particularly alcoholic liver diseases (ALD). The extent of liver damage caused by ethanol correlates with increased oxidative stress and accumulation of lipids in t…
Intraosseous hemangioma with aneurysmal bone cyst-like changes of the hyoid bone: Case report and literature review Open
Rationale: Intraosseous hemangioma is a rare benign vascular tumor of the bone that can affect any body part; however, the most common site is the vertebra, followed by calvarial bones. Patient concerns: We present a case of intraosseous h…
Anticancer Effect of Gallic Acid on Acidity-Induced Invasion of MCF7 Breast Cancer Cells Open
The acidic tumor environment has emerged as a crucial factor influencing the metastatic potential of cancer. We investigated the effect of an acidic environment on the acquisition of metastatic properties in MCF7 breast cancer cells and ex…
View article: Supplementary Figure Legends 1-7, Table Legends 1-5 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Supplementary Figure Legends 1-7, Table Legends 1-5 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
PDF file - 144K
View article: Supplementary Methods from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Supplementary Methods from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
PDF file - 152K, File includes Western blotting, RT-PCR, real-time PCR, and nuclear fractionation
View article: Supplementary Tables 1-5 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Supplementary Tables 1-5 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
PDF file - 373K, Supplemental Tables S1-S5 include shRNA target sequences (Table S1), primers for RT-PCR, real-time PCR, and ChIP assays (Table S2), regulation of COX subunits and assembly factors (Table S3), Snail binding site in promoter…
View article: Data from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Data from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
Wnt signaling plays a critical role in embryonic development, and its deregulation is closely linked to the occurrence of a number of malignant tumors, including breast and colon cancer. The pathway also induces Snail-dependent epithelial-…
View article: Supplementary Figure Legends 1-7, Table Legends 1-5 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Supplementary Figure Legends 1-7, Table Legends 1-5 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
PDF file - 144K
View article: Supplementary Figures 1-7 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Supplementary Figures 1-7 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
PDF file - 3.8MB, Supplemental Figures S1-S7 include the Induction of EMT in MCF-7 cells (Figure S1), the effects of Wnt on mitochondrial mass (Figure S2), Ponceau S staining corresponding to Figure 4A (Figure S3), ChIP assays using Wnt3a-…
View article: Data from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Data from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
Wnt signaling plays a critical role in embryonic development, and its deregulation is closely linked to the occurrence of a number of malignant tumors, including breast and colon cancer. The pathway also induces Snail-dependent epithelial-…
View article: Supplementary Figures 1-7 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Supplementary Figures 1-7 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
PDF file - 3.8MB, Supplemental Figures S1-S7 include the Induction of EMT in MCF-7 cells (Figure S1), the effects of Wnt on mitochondrial mass (Figure S2), Ponceau S staining corresponding to Figure 4A (Figure S3), ChIP assays using Wnt3a-…
View article: Supplementary Tables 1-5 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Supplementary Tables 1-5 from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
PDF file - 373K, Supplemental Tables S1-S5 include shRNA target sequences (Table S1), primers for RT-PCR, real-time PCR, and ChIP assays (Table S2), regulation of COX subunits and assembly factors (Table S3), Snail binding site in promoter…
View article: Supplementary Methods from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism
Supplementary Methods from Wnt/Snail Signaling Regulates Cytochrome <i>c</i> Oxidase and Glucose Metabolism Open
PDF file - 152K, File includes Western blotting, RT-PCR, real-time PCR, and nuclear fractionation
Molecular Basis of Resveratrol-Induced Resensitization of Acquired Drug-Resistant Cancer Cells Open
Multidrug resistance (MDR) to anticancer drugs remains a serious obstacle to the success of cancer chemotherapy. Resveratrol, a polyphenol, present in natural products exerts anticancer activity and acts as a potential MDR inhibitor in var…
[High expression of miR-3682-3p is an unfavorable prognostic factor of hepatocellular carcinoma]. Open
MiR-3682-3p is up-regulated in HCC to serve as a significant factor that contributes to the occurrence and a poor prognosis of HCC.
Intra-muscular follicular dendritic cell sarcoma in the thigh Open
Rationale: Follicular dendritic cell sarcoma (FDCS) is an intermediate-grade malignancy originating from follicular dendritic cells. Nodal FDCS is the most common type, meaning that the extranodal type may not be recognized and could be ea…
Cryptococcal infection presenting as soft tissue abscess and arthritis Open
Rationale: Cryptococcal infection has been documented in immunocompromised patients. AIDS and renal transplant recipients account for majority of the cases. Most cases present with central nervous system or disseminated disease, with only …
Extracellular Acidity-mediated Expression of cPLA2γ Confers Resistance in Gastric Cancer Cells Open
Acidity-induced cPLA2γ expression may exert protective effects by imparting resistance to the gastric cancer cells under acidic environment.
Increased serum nesfatin-1 levels in patients with acromegaly Open
Nesfatin-1 was identified as a satiety factor involved in the regulation of metabolism. Altered levels of circulating nesfatin-1 had been observed in a variety of diseases characterized by energy imbalance. However, there was no published …
Role of Death Receptors-associated Lipid Rafts in Oxaliplatin-induced Death Mode Regulation of HepG2 Cells Open
UDCA promotes lipid raft localization of multiple death receptors, thereby contributing to a shift of cell death mode from oxaliplatin-induced necrotic death to apoptosis in HepG2 cells.
Extracellular acidity‑induced expression of Kallikrein‑related peptidases 7 and 8 is involved in increased invasiveness of gastric cancer cells Open
In several cancers, the acidic microenvironment of cancer cells has been implicated in enhanced malignancy and metastasis. In the present study, it was observed that gastric cancer cell lines, SNU601 and AGS, exposed to an acidic medium ha…
Rare Case of Renal-type Clear Cell Carcinoma of the Prostate and Review of the Literature Open
This was a case of RTCCC arising in the prostate. RTCCC of the prostate is extremely rare and shows very similar histological and immunohistochemical features to those of CCC occurring in the kidney. Pathologists should be aware of such an…
Expression and Prognostic Significance of CDK8 and β-Catenin in Hepatocellular Carcinoma Open
Inhibition of CDK8 and/or nuclear β-catenin expression pattern could serve as a promising therapeutic strategy for the treatment of HCC.
Ellagic Acid Inhibits Extracellular Acidity-Induced Invasiveness and Expression of COX1, COX2, Snail, Twist 1, and c-myc in Gastric Carcinoma Cells Open
Extracellular acidity has been implicated in enhanced malignancy and metastatic features in various cancer cells. Gastric cancer cell lines (AGS and SNU601) maintained in an acidic medium have increased motility and invasiveness. In this s…