Izzat Zulkiflee
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View article: Regenerative strategies for intervertebral disc degeneration
Regenerative strategies for intervertebral disc degeneration Open
Low back pain (LBP) is a global health problem, primarily caused by intervertebral disc (IVD) degeneration. Current treatments focus on symptom relief without addressing the underlying degenerative mechanisms. Regenerative strategies have …
View article: Human cadaveric spine dissection: A protocol for harvesting lumbar intervertebral discs from body donors
Human cadaveric spine dissection: A protocol for harvesting lumbar intervertebral discs from body donors Open
In spine research, human degenerative discs are commonly procured from patients undergoing spinal surgery; however, the acquisition of healthy discs as age-matched controls remains highly restricted. This study establishes a protocol for d…
View article: Three-dimensional hydrogel with human Wharton jelly-derived mesenchymal stem cells towards nucleus pulposus niche
Three-dimensional hydrogel with human Wharton jelly-derived mesenchymal stem cells towards nucleus pulposus niche Open
Introduction: A regenerative strategy employing extracellular matrix (ECM)-based biomaterials and stem cells provide a better approach to mimicking the three-dimensional (3D) microenvironment of intervertebral disc for endogenous tissue re…
View article: Plasma-Polymerised Antibacterial Coating of Ovine Tendon Collagen Type I (OTC) Crosslinked with Genipin (GNP) and Dehydrothermal-Crosslinked (DHT) as a Cutaneous Substitute for Wound Healing
Plasma-Polymerised Antibacterial Coating of Ovine Tendon Collagen Type I (OTC) Crosslinked with Genipin (GNP) and Dehydrothermal-Crosslinked (DHT) as a Cutaneous Substitute for Wound Healing Open
Tissue engineering products have grown in popularity as a therapeutic approach for chronic wounds and burns. However, some drawbacks include additional steps and a lack of antibacterial capacities, both of which need to be addressed to tre…
View article: Characterization of Dual-Layer Hybrid Biomatrix for Future Use in Cutaneous Wound Healing
Characterization of Dual-Layer Hybrid Biomatrix for Future Use in Cutaneous Wound Healing Open
A skin wound without immediate treatment could delay wound healing and may lead to death after severe infection (sepsis). Any interruption or inappropriate normal wound healing, mainly in these wounds, commonly resulted in prolonged and ex…
View article: Silicon-Based Scaffold for Wound Healing Skin Regeneration Applications: A Concise Review
Silicon-Based Scaffold for Wound Healing Skin Regeneration Applications: A Concise Review Open
Silicon has made its breakthrough in various industries, including clinical and biomedical applications. Silicon-based biomaterials that were fabricated into various types of scaffolds may attract interest due to their highly favorable pro…
View article: A Comprehensive Review on Collagen Type I Development of Biomaterials for Tissue Engineering: From Biosynthesis to Bioscaffold
A Comprehensive Review on Collagen Type I Development of Biomaterials for Tissue Engineering: From Biosynthesis to Bioscaffold Open
Collagen is the most abundant structural protein found in humans and mammals, particularly in the extracellular matrix (ECM). Its primary function is to hold the body together. The collagen superfamily of proteins includes over 20 types th…
View article: Cellular Interaction of Human Skin Cells towards Natural Bioink via 3D-Bioprinting Technologies for Chronic Wound: A Comprehensive Review
Cellular Interaction of Human Skin Cells towards Natural Bioink via 3D-Bioprinting Technologies for Chronic Wound: A Comprehensive Review Open
Skin substitutes can provide a temporary or permanent treatment option for chronic wounds. The selection of skin substitutes depends on several factors, including the type of wound and its severity. Full-thickness skin grafts (SGs) require…
View article: Gelatin-Polyvinyl Alcohol Film for Tissue Engineering: A Concise Review
Gelatin-Polyvinyl Alcohol Film for Tissue Engineering: A Concise Review Open
The field of biomaterials has been steadily expanding as a large number of pharmaceutical and manufacturing companies invest in research in order to commercialize biomaterial products. Various three-dimensional biomaterials have been explo…