James McLaughlin
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View article: Performance of Colorimetric Lateral Flow Immunoassays for Renal Function Evaluation with Human Serum Cystatin C
Performance of Colorimetric Lateral Flow Immunoassays for Renal Function Evaluation with Human Serum Cystatin C Open
Chronic kidney disease (CKD) is associated with heart failure and neurological disorders. Therefore, point-of-care (POC) detection of CKD is essential, allowing disease monitoring from home and alleviating healthcare professionals’ workloa…
View article: Aptamer-enhanced ultrasensitive electrochemical detection of HER-2 in breast cancer diagnosis using ZnO tetrapod-K4PTC nanohybrids
Aptamer-enhanced ultrasensitive electrochemical detection of HER-2 in breast cancer diagnosis using ZnO tetrapod-K4PTC nanohybrids Open
Breast cancer continues to be a severe global health issue, emphasizing the critical need for accurate and timely detection and screening of large numbers of patients. This ailment places an enormous strain on healthcare resources and pose…
View article: The Impact of an Exam Retake Policy on Student Anxiety, Academic Performance, and Long-Term Learning Outcomes in High School Settings
The Impact of an Exam Retake Policy on Student Anxiety, Academic Performance, and Long-Term Learning Outcomes in High School Settings Open
School exam retake policies are an ongoing debate in education, with proponents arguing for and against them. This study examines the long-term benefits of retake policies in high schools, which can have a direct impact on student anxiety …
View article: High-Performance Paper-Based DNA-Conjugated Ti<sub>3</sub>C<sub>2</sub>T<sub> <i>x</i> </sub> Bionanoelectrode for Rapid Point-of-Care Detection of HPV-16
High-Performance Paper-Based DNA-Conjugated Ti<sub>3</sub>C<sub>2</sub>T<sub> <i>x</i> </sub> Bionanoelectrode for Rapid Point-of-Care Detection of HPV-16 Open
Cervical cancer remains a significant global health concern, with high-risk human papillomavirus (HR-HPV), particularly the genotype 16, identified as a key etiological factor with a significantly high mortality rate. The conventional diag…
View article: Reduced Heating Wireless Energy Transmission System for Powering Implanted Circulatory Assist Devices: Benchtop and In-Vivo Studies
Reduced Heating Wireless Energy Transmission System for Powering Implanted Circulatory Assist Devices: Benchtop and In-Vivo Studies Open
This study aimed to develop a novel Transdermal Energy Transmission System (TETS) device that addresses the driveline complications faced by patients with advanced heart failure (HF). Our TETS device utilizes a two-channel configuration wi…
View article: Feasibility of a Novel Multiplex Lateral Flow Device for the Simultaneous Detection of Thyroid Stimulating Hormone And C-Reactive Protein for Diagnosis of Hypothyroidism
Feasibility of a Novel Multiplex Lateral Flow Device for the Simultaneous Detection of Thyroid Stimulating Hormone And C-Reactive Protein for Diagnosis of Hypothyroidism Open
View article: Integrating the international medical graduate
Integrating the international medical graduate Open
View article: Enhancing Sensitivity of Point-of-Care Thyroid Diagnosis via Computational Analysis of Lateral Flow Assay Images Using Novel Textural Features and Hybrid-AI Models
Enhancing Sensitivity of Point-of-Care Thyroid Diagnosis via Computational Analysis of Lateral Flow Assay Images Using Novel Textural Features and Hybrid-AI Models Open
Lateral flow assays are widely used in point-of-care diagnostics but face challenges in sensitivity and accuracy when detecting low analyte concentrations, such as thyroid-stimulating hormone biomarkers. This study aims to enhance assay pe…
View article: Machine Learning-Based Structural Health Monitoring Technique for Crack Detection and Localisation Using Bluetooth Strain Gauge Sensor Network
Machine Learning-Based Structural Health Monitoring Technique for Crack Detection and Localisation Using Bluetooth Strain Gauge Sensor Network Open
Within the domain of Structural Health Monitoring (SHM), conventional approaches generally are complicated, destructive, and time-consuming. It also necessitates an extensive array of sensors to effectively evaluate and monitor the structu…
View article: Machine Learning-Based Structural Health Monitoring Technique for Crack Detection and Localisation Using Bluetooth Strain Gauge Sensor Network
Machine Learning-Based Structural Health Monitoring Technique for Crack Detection and Localisation Using Bluetooth Strain Gauge Sensor Network Open
Conventional approaches in Structural Health Monitoring (SHM) tend to be complex, destructive, and time-intensive. Additionally, they often require a large number of sensors to thoroughly assess structural integrity. In this study, we pres…
View article: Detecting Respiratory Viruses Using a Portable NIR Spectrometer—A Preliminary Exploration with a Data Driven Approach
Detecting Respiratory Viruses Using a Portable NIR Spectrometer—A Preliminary Exploration with a Data Driven Approach Open
Respiratory viruses’ detection is vitally important in coping with pandemics such as COVID-19. Conventional methods typically require laboratory-based, high-cost equipment. An emerging alternative method is Near-Infrared (NIR) spectroscopy…
View article: Fabrication of Gold Nanoparticles Embedded Laser-Induced Graphene (LIG) Electrode for Hydrogen Evolution Reaction
Fabrication of Gold Nanoparticles Embedded Laser-Induced Graphene (LIG) Electrode for Hydrogen Evolution Reaction Open
The advancement of renewable energy technologies like water electrolysis and hydrogen fuel cells relies on the fabrication of effective and reliable catalysts for the hydrogen evolution process (HER). In this regard, we report gold nanopar…
View article: Influence of the Training Set Composition on the Estimation Performance of Linear ECG-Lead Transformations
Influence of the Training Set Composition on the Estimation Performance of Linear ECG-Lead Transformations Open
Linear ECG-lead transformations (LELTs) are used to estimate unrecorded target leads by applying a number of recorded basis leads to a LELT matrix. Such LELT matrices are commonly developed using training datasets that are composed of ECGs…
View article: A Simple Standard for Ontological Mappings 2023: Updates on data model, collaborations and tooling
A Simple Standard for Ontological Mappings 2023: Updates on data model, collaborations and tooling Open
The Simple Standard for Ontological Mappings (SSSOM) was first published in December 2021 (v. 0.9). After a number of revisions prompted by community feedback, we have published version 0.15.0 in July 2023. Here we report on the progress m…
View article: Data Mining and Fusion Framework for In-Home Monitoring Applications
Data Mining and Fusion Framework for In-Home Monitoring Applications Open
Sensor Data Fusion (SDT) algorithms and models have been widely used in diverse applications. One of the main challenges of SDT includes how to deal with heterogeneous and complex datasets with different formats. The present work utilised …
View article: Data Mining and Fusion Framework for In-Home Monitoring Applications
Data Mining and Fusion Framework for In-Home Monitoring Applications Open
Sensor fusion algorithms and models have been widely used in recent times. Although research evidence has informed the use of sensor fusion models in diverse applications, there is room for improvement, especially in home-based health moni…
View article: Development of hybrid 3D-printed structure with aligned drug-loaded fibres using in-situ custom designed templates
Development of hybrid 3D-printed structure with aligned drug-loaded fibres using in-situ custom designed templates Open
View article: A Simple Standard for Ontological Mappings 2023: Updates on data model, collaborations and tooling
A Simple Standard for Ontological Mappings 2023: Updates on data model, collaborations and tooling Open
The Simple Standard for Ontological Mappings (SSSOM) was first published in December 2021 (v. 0.9). After a number of revisions prompted by community feedback, we have published version 0.15.0 in July 2023. Here we report on the progress m…
View article: Epileptic multi-seizure type classification using electroencephalogram signals from the Temple University Hospital Seizure Corpus: A review
Epileptic multi-seizure type classification using electroencephalogram signals from the Temple University Hospital Seizure Corpus: A review Open
Epilepsy is one of the most paramount neurological diseases, affecting about 1% of the world's population. Seizure detection and classification are difficult tasks and are ongoing challenges in biomedical signal processing to enhance medic…
View article: Investigating Temporal Features of Carotid Intima-Media Thickness from Ultrasound Imaging with Recurrent Neural Networks
Investigating Temporal Features of Carotid Intima-Media Thickness from Ultrasound Imaging with Recurrent Neural Networks Open
Measuring carotid intima-media thickness (cIMT) of the Common Carotid Artery (CCA) via B-mode ultrasound imaging is a non-invasive yet effective way to monitor and assess cardiovascular risk. Recent studies using Convolutional Neural Netwo…
View article: Effect of Selenium Nanoparticle Size on IL-6 Detection Sensitivity in a Lateral Flow Device
Effect of Selenium Nanoparticle Size on IL-6 Detection Sensitivity in a Lateral Flow Device Open
Sepsis is the body's response to an infection. Existing diagnostic testing equipment is not available in primary care settings and requires long waiting times. Lateral flow devices (LFDs) could be employed in point-of-care (POC) settings f…
View article: Assessment of hemodynamic indices of conjunctival microvascular function in patients with coronary microvascular dysfunction
Assessment of hemodynamic indices of conjunctival microvascular function in patients with coronary microvascular dysfunction Open
View article: Assessment of Indices of Conjunctival Microvascular Function in Patients With and Without Obstructive Coronary Artery Disease
Assessment of Indices of Conjunctival Microvascular Function in Patients With and Without Obstructive Coronary Artery Disease Open
View article: Evaluation of Pulse Transit Time for Different Sensing Methodologies of Arterial Waveforms
Evaluation of Pulse Transit Time for Different Sensing Methodologies of Arterial Waveforms Open
We perform a novel comparative analysis between optically and mechanically derived pulse transit time (PTT), which is a universally employed technique for cuffless blood pressure (BP) estimation. Two inline photoplethysmogram (PPG) sensors…
View article: Harnessing Dermal Blood Flow to Mitigate Skin Heating Effects in Wireless Transdermal Energy Systems for Driving Heart Pumps
Harnessing Dermal Blood Flow to Mitigate Skin Heating Effects in Wireless Transdermal Energy Systems for Driving Heart Pumps Open
This work focuses on the thermal analysis of a transdermal wireless radiofrequency (RF) energy transfer system, to power artificial heart pumps, particularly leftventricular assist devices (LVADs).We aim to understand the blood perfusion f…
View article: AI-enabled ECG combined with dry electrode sensors for population-based screening of Atrial Fibrillation.
AI-enabled ECG combined with dry electrode sensors for population-based screening of Atrial Fibrillation. Open
This study assessed the performance of a deep neural network (PulseAI, Belfast, United Kingdom) used in conjunction with a dry-electrode ECG sensor device (RhythmPad, D&FT, United Kingdom) to detect AF automatically.Simultaneous pairs of 1…
View article: A novel patches-selection method for the classification of point-of-care biosensing lateral flow assays with cardiac biomarkers
A novel patches-selection method for the classification of point-of-care biosensing lateral flow assays with cardiac biomarkers Open
View article: Reply on RC2
Reply on RC2 Open
Abstract. Coral reefs face increasing pressures in response to unprecedented rates of environmental change at present. The coral reef physical framework is formed through the production of calcium carbonate (CaCO3
View article: Reply on RC1
Reply on RC1 Open
Coral reefs face increasing pressures in response to unprecedented rates of environmental change at present. The coral reef physical framework is formed through the production of calcium carbonate (CaCO3) and maintained by marine organisms…
View article: A Refined Hot Melt Printing Technique with Real-Time CT Imaging Capability
A Refined Hot Melt Printing Technique with Real-Time CT Imaging Capability Open
Personalised drug delivery systems with the ability to offer real-time imaging and control release are an advancement in diagnostic and therapeutic applications. This allows for a tailored drug dosage specific to the patient with a release…