Amina Jega Yusuf
YOU?
Author Swipe
View article: Integrated in vivo and in silico evaluation of antimalarial compounds from Vernonia ambigua leaves identified by GC-MS profiling
Integrated in vivo and in silico evaluation of antimalarial compounds from Vernonia ambigua leaves identified by GC-MS profiling Open
Background Malaria remains a global health challenge, and the emergence of drug-resistant Plasmodium strains has necessitated the search for new antimalarial agents. Vernonia ambigua is used traditionally to treat malaria in parts of Afric…
View article: Phytochemical, Antibacterial and Characterization of 9-methoxy-12-phenyl-dodec-10-enoic acid-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-ylester Isolated from Acacia macrostachya leaves
Phytochemical, Antibacterial and Characterization of 9-methoxy-12-phenyl-dodec-10-enoic acid-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-ylester Isolated from Acacia macrostachya leaves Open
Acacia macrostachya is plant usually a tree belong to family Mimosaceae (Fabaceae), it is popularly known as “Gardaye” in Hausa Language (Sokoto). A. macrostachya is one of such useful plants in African traditional medicine. It is used to …
View article: Neocarya macrophylla ethyl acetate fraction attenuates oxidative stress and inflammation in high-fat diet and streptozotocin-induced diabetic rats
Neocarya macrophylla ethyl acetate fraction attenuates oxidative stress and inflammation in high-fat diet and streptozotocin-induced diabetic rats Open
Oxidative stress and inflammation drive diabetes. Conventional treatments inadequately target these. Neocarya macrophylla shows preliminary antioxidant promise. This study aims to investigate its antioxidant and anti-inflammatory effects i…
View article: Repurposing calcium channel blockers and cholinesterase inhibitors for antisnake venom therapy: a mechanistic literature review
Repurposing calcium channel blockers and cholinesterase inhibitors for antisnake venom therapy: a mechanistic literature review Open
Snakebite envenomation remains a critical global health challenge, particularly in regions with high snakebite incidence and limited access to effective antivenom. The complex mixture of venom toxins including phospholipases, metalloprotei…
View article: Dynamic stability and linear vibration analysis of functionally graded axially moving pipes via the finite element approach
Dynamic stability and linear vibration analysis of functionally graded axially moving pipes via the finite element approach Open
This paper presents a finite element-based numerical investigation of the dynamic stability and linear vibration characteristics of an axially moving functionally graded pipe system. Functionally graded materials (FGMs) provide gradual var…
View article: STIGMASTEROL ISOLATION AND ANTICONVULSANT ACTIVITY OF METHANOL EXTRACT FROM THE AERIAL PARTS OF INDIGOFERA STENOPHYLLA (FABACEAE)
STIGMASTEROL ISOLATION AND ANTICONVULSANT ACTIVITY OF METHANOL EXTRACT FROM THE AERIAL PARTS OF INDIGOFERA STENOPHYLLA (FABACEAE) Open
View article: Comparative Label-Based Proteomics of Venoms from Echis ocellatus, Naja nigricollis, and Bitis arietans
Comparative Label-Based Proteomics of Venoms from Echis ocellatus, Naja nigricollis, and Bitis arietans Open
Background: Snake envenomation is a major public health issue in Nigeria, primarily due to bites from Echis ocellatus, Naja nigricollis, and Bitis arietans. Understanding their venom composition is essential for effective antivenom develop…
View article: Preclinical Studies of a Multi-Component Herbal Therapy (Rogeria adenophylla J.Gay ex Delile, Bombax costatum Pellegr. & Vuillet, Diospyros mespiliformis Hochst. Ex A.DC. and Entada africana Guill. & Perr.) for the Management of Snake Envenomation
Preclinical Studies of a Multi-Component Herbal Therapy (Rogeria adenophylla J.Gay ex Delile, Bombax costatum Pellegr. & Vuillet, Diospyros mespiliformis Hochst. Ex A.DC. and Entada africana Guill. & Perr.) for the Management of Snake Envenomation Open
In Northwestern Nigeria, Rogeria adenophylla, Bombax costatum, Diospyros mespiliformis, and Entada africana are traditionally used to treat snakebite envenomation. This study evaluated their antivenom properties against Naja pallida and Ec…
View article: A NOVEL PHENOLIC DERIVATIVE FROM THE AERIAL PARTS OF INDIGOFERRA ARRECTA HOCHST. EX A.RICH (PAPILIONOICEAE)
A NOVEL PHENOLIC DERIVATIVE FROM THE AERIAL PARTS OF INDIGOFERRA ARRECTA HOCHST. EX A.RICH (PAPILIONOICEAE) Open
Indigofera arrecta (Papilionoideae) is a widely recognized medicinal plant traditionally used in various cultures for the treatment of ailments such as epilepsy, snakebites, and jaundice. The therapeutic potential of this plant is attribut…
View article: ACUTE TOXICITY TEST AND EVALUATION OF ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF METHANOL LEAF EXTRACT OF OCHNA KIBBIENSIS HUTCH AND DALZ (OCHNACEAE)
ACUTE TOXICITY TEST AND EVALUATION OF ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF METHANOL LEAF EXTRACT OF OCHNA KIBBIENSIS HUTCH AND DALZ (OCHNACEAE) Open
Pain is an unpleasant feeling caused by the stimulation of pain receptors. Inflammation is a complex response to exogenous and endogenous stimuli. Ochna kibbiensis Hutz and Dalz (Ochnaceae) is majorly used traditionally in the treatment of…
View article: Isolation and Characterization of Lupeol and Betulinic Acid from the Aerial Parts of <i>Euphorbia convolvuloides</i>
Isolation and Characterization of Lupeol and Betulinic Acid from the Aerial Parts of <i>Euphorbia convolvuloides</i> Open
Euphorbia convolvuloides is used in traditional medicine to treat bacterial infection, peptic ulcers and asthma among others. The aim of this research is to isolate and characterize the antibacterial constituent(s) from the aerial parts of…
View article: Identification of possible antimalarial constituent(s) from the leaves of Ochna kibbiensis: A phytochemical, in vivo and in silico approaches
Identification of possible antimalarial constituent(s) from the leaves of Ochna kibbiensis: A phytochemical, in vivo and in silico approaches Open
Background: Malaria is a major public health problem especially in developing countries such as Nigeria and its treatment is being compromised by resistance of the parasite to most of the available drugs, including the current gold-standar…
View article: Structural characterization and in silico evaluation of bioactive compounds from Rhus cotinus (Syn. Cotinus coggygria) roots as potential EGFR inhibitors for brain Cancer
Structural characterization and in silico evaluation of bioactive compounds from Rhus cotinus (Syn. Cotinus coggygria) roots as potential EGFR inhibitors for brain Cancer Open
Brain cancer, particularly glioblastoma, represents a significant therapeutic challenge due to its aggressive nature and limited treatment options. The epidermal growth factor receptor (EGFR) has emerged as a crucial target for brain cance…
View article: Beyond analgesia: repurposing NSAIDs as a novel strategy in antivenom therapy against Naja nigricollis envenomation
Beyond analgesia: repurposing NSAIDs as a novel strategy in antivenom therapy against Naja nigricollis envenomation Open
View article: Isolation of Rutin from Neocarya macrophylla leaves (Sabine) Prance (Chrysobalanaceae)
Isolation of Rutin from Neocarya macrophylla leaves (Sabine) Prance (Chrysobalanaceae) Open
Neocarya macrophylla is a medicinal plant which belong to the Chrysobalanaceae family. It has many ethnomedicinal uses such as treatment of snake bite, pain and inflammation. In this work, a flavonoid diglycoside was isolated from the ethy…
View article: Beyond Analgesia: Repurposing NSAIDs as a Novel Strategy in Antivenom Therapy against Naja nigricollis Envenomation
Beyond Analgesia: Repurposing NSAIDs as a Novel Strategy in Antivenom Therapy against Naja nigricollis Envenomation Open
Objective This study aimed to explore the potential of repurposing non-steroidal anti-inflammatory drugs (NSAIDs) as antisnake venom agents using experimental and computational approaches. Data Description Virtual screening of 20 NSAIDs al…
View article: Synergistic use of pomegranate in homoeopathic dilutions for skin ailments
Synergistic use of pomegranate in homoeopathic dilutions for skin ailments Open
View article: Exploring the Antidiabetic Potential of Neocarya macrophylla (Nm) Leaf Fractions: A Comprehensive Study on Hypoglycemic Activity, Body Mass Index, and Hematological Parameters in High-Fat Diet/ Streptozotocin-Induced Diabetic Rat
Exploring the Antidiabetic Potential of Neocarya macrophylla (Nm) Leaf Fractions: A Comprehensive Study on Hypoglycemic Activity, Body Mass Index, and Hematological Parameters in High-Fat Diet/ Streptozotocin-Induced Diabetic Rat Open
The prevalence of diabetes mellitus (DM) continues to rise globally, posing significant health challenges and burdens. This metabolic disorder, characterized by elevated blood glucose levels, contributes to various complications including …
View article: Impact of Urban Expansion on Migratory Birds in the Lagos Wetlands: Breeding Habits and Population Dynamics
Impact of Urban Expansion on Migratory Birds in the Lagos Wetlands: Breeding Habits and Population Dynamics Open
This research delves into the complex interactions between urban expansion and migratory bird populations in the Lagos wetlands, specifically examining how changes in urban landscapes influence breeding habits and population dynamics. The …
View article: Characterization and Evaluation of Antimicrobial Activity of Sorbitan Isolated from the Leaves of <i>Securidaca longipedunculata</i> (Fresen)
Characterization and Evaluation of Antimicrobial Activity of Sorbitan Isolated from the Leaves of <i>Securidaca longipedunculata</i> (Fresen) Open
Securidaca longipedunculata is a shrub of the family Polygalaceae. It is a potent medicinal plant used in management of microbial infection others. The aim of this study is to characterize, and evaluate the antimicrobial activity of sorbit…
View article: Mental Health Burden and Facilitators Among Frontline Healthcare Professionals in Nigeria Amid COVID-19 Pandemic: A Cross-sectional Study
Mental Health Burden and Facilitators Among Frontline Healthcare Professionals in Nigeria Amid COVID-19 Pandemic: A Cross-sectional Study Open
A BSTRACT Background: During the COVID-19 pandemic, the frontline healthcare providers faced significant mental health stressors. Previous pandemics have revealed the need for psychosocial support and healthy coping mechanisms to mitigate …
View article: Isolation and Characterization of Antimicrobial Constituent(s) from the Stem of Cissus populnea Guill. & Perr.
Isolation and Characterization of Antimicrobial Constituent(s) from the Stem of Cissus populnea Guill. & Perr. Open
Cissus populnea Guill. & Perr. (Vitaceae) is used in traditional medicine to treat microbial infections, venereal diseases and infertility, among others. The aim of this research is to isolate and characterize the antimicrobial constituent…
View article: Comparative Antimicrobial Activity of Securidaca longipedunculata (Fresen) Extracts on Selected Human Pathogens
Comparative Antimicrobial Activity of Securidaca longipedunculata (Fresen) Extracts on Selected Human Pathogens Open
The escalating trend of microbial resistance has become a pressing global concern, challenging the effectiveness of antimicrobial agents in treating infections. This study was aimed at evaluating the antimicrobial activity of the n-hexane,…
View article: Structural Characterization and in Silico Evaluation of Bioactive Compounds from Rhus Cotinus (Syn. Cotinus Coggygria) Roots as Potential Egfr Inhibitors for Brain Cancer
Structural Characterization and in Silico Evaluation of Bioactive Compounds from Rhus Cotinus (Syn. Cotinus Coggygria) Roots as Potential Egfr Inhibitors for Brain Cancer Open
View article: Identification of Possible Antimalarial Constituents from the Leaves of Ochna Kibbiensis Hutch. & Dalziel: A Phytochemical and in Silico Approach
Identification of Possible Antimalarial Constituents from the Leaves of Ochna Kibbiensis Hutch. & Dalziel: A Phytochemical and in Silico Approach Open
View article: Neocarya macrophylla (Chrysobalanaceae): Review of taxonomy, ethnobotany, phytochemistry and biological activities
Neocarya macrophylla (Chrysobalanaceae): Review of taxonomy, ethnobotany, phytochemistry and biological activities Open
The Neocarya macrophylla plant is used traditionally for food, medicinal, spiritual and industrial purposes. It is also used as a soap, dye, glue, fodder, termite repellent, firewood and for structural materials. Few studies on the physico…
View article: Unveiling the Antiophidian Potential of Epicatechin and Isoquercetin from Tapinanthus Globiferus Growing on Acacia Nilotica: An in Silico and in Vitro Studies
Unveiling the Antiophidian Potential of Epicatechin and Isoquercetin from Tapinanthus Globiferus Growing on Acacia Nilotica: An in Silico and in Vitro Studies Open
View article: Review of: "Acacia Pycnantha Gum Exudates Recognised As a Traditional Food in Two Countries May Have Economic Potential"
Review of: "Acacia Pycnantha Gum Exudates Recognised As a Traditional Food in Two Countries May Have Economic Potential" Open
View article: Review of: "Acacia pycnantha gum exudates recognised as a traditional food in two countries may have economic potential"
Review of: "Acacia pycnantha gum exudates recognised as a traditional food in two countries may have economic potential" Open
Potential competing interests: No potential competing
View article: Isolation and Characterization of Antimicrobial Constituent(s) from the Stem of <em>Cissus populnea</em> Guill. & Perr.
Isolation and Characterization of Antimicrobial Constituent(s) from the Stem of <em>Cissus populnea</em> Guill. & Perr. Open
Cissus populnea Guill. & Perr. (Vitaceae) is used in traditional medicine to treat microbial infec-tions, venereal diseases, and infertility, among others. The aim of the research is to isolate and characterize the antimicrobial consti…