Explanipedia

Functional connectivity of thalamic nuclei during sensorimotor task-based fMRI at 9.4 Tesla Open

Edyta Charyasz, Michael Erb, J Bause, Rahel Heule, Benjamin Bender , et al. · 2025

The thalamus is the brain’s central communication hub, playing a key role in processing and relaying sensorimotor and cognitive information between the cerebral cortex and other brain regions. It consists of specific and non-specific nucle…

Submillimeter Ultra-High Field 9.4 T Brain MR Image Collection and Manual Cortical Segmentations Open

Lucas Mahler, Julius Steiglechner, Benjamin Bender, Tobias Lindig, Dana Ramadan , et al. · 2025

The UltraCortex repository houses magnetic resonance imaging data of the human brain obtained at an ultra-high field strength of 9.4 T. It contains 86 structural MR images with spatial resolutions ranging from 0.6 to 0.8 mm. Additionally, …

Macrovascular contributions to resting-state fMRI signals: A comparison between EPI and bSSFP at 9.4 Tesla Open

Dana Ramadan, Sebastian Mueller, Ruediger Stirnberg, Dario Bosch, Philipp Ehses , et al. · 2024

The draining-vein bias of T2*-weighted sequences, like gradient echo echo-planar imaging (GRE-EPI), can limit the spatial specificity of functional MRI (fMRI). The underlying extravascular signal changes increase with field strength (B0) a…

UltraCortex: Submillimeter Ultra-High Field 9.4 T Brain MR Image Collection and Manual Cortical Segmentations Open

Lucas Mahler, Julius Steiglechner, Benjamin Bender, Tobias Lindig, Dana Ramadan , et al. · 2024

The UltraCortex repository ( https://www.ultracortex.org ) houses magnetic resonance imaging data of the human brain obtained at an ultra-high field strength of 9.4 T. It contains 86 structural MR images with spatial resolutions ranging fr…

UltraCortex: Submillimeter Ultra-High Field 9.4 T Brain MR Image Collection and Manual Cortical Segmentations Open

Lucas Mahler, Julius Steiglechner, Benjamin Bender, Tobias Lindig, Dana Ramadan , et al. · 2024

The UltraCortex repository (https://www.ultracortex.org) houses magnetic resonance imaging data of the human brain obtained at an ultra-high field strength of 9.4 T. It contains 86 structural MR images with spatial resolutions ranging from…

Protocol for 3D virtual histology of unstained human brain tissue using synchrotron radiation phase-contrast microtomography Open

Ju Young Lee, Sandro Donato, Andreas F. Mack, Ulrich Mattheus, Giuliana Tromba , et al. · 2024

X-ray phase-contrast micro computed tomography using synchrotron radiation (SR PhC-µCT) offers unique 3D imaging capabilities for visualizing microstructure of the human brain. Its applicability for unstained soft tissue is an area of acti…

Protocol for 3D Virtual Histology of Unstained Human Brain Tissue using Synchrotron Radiation Phase-Contrast Microtomography Open

Ju Young Lee, Sandro Donato, Andreas F. Mack, Ulrich Mattheus, Giuliana Tromba , et al. · 2023

X-ray phase-contrast micro computed tomography using synchrotron radiation (SR PhC-µCT) offers unique 3D imaging capabilities for visualizing microstructure of the human brain. Its applicability for unstained soft tissue is an area of acti…

Prediction of motion induced magnetic fields for human brain MRI at 3 T Open

Jiazheng Zhou, G Hagberg, Ali Aghaeifar, J Bause, Maxim Zaitsev , et al. · 2023

Objective Maps of B 0 field inhomogeneities are often used to improve MRI image quality, even in a retrospective fashion. These field inhomogeneities depend on the exact head position within the static field but acquiring field maps (FM) a…

Functional mapping of sensorimotor activation in the human thalamus at 9.4 Tesla Open

Edyta Charyasz, Rahel Heule, Francesko Molla, Michael Erb, Vinod Kumar , et al. · 2023

Although the thalamus is perceived as a passive relay station for almost all sensory signals, the function of individual thalamic nuclei remains unresolved. In the present study, we aimed to identify the sensorimotor nuclei of the thalamus…

Prediction of motion induced magnetic fields for human brain MRI at 3T Open

Jiazheng Zhou, G Hagberg, Ali Aghaeifar, J Bause, Maxim Zaitsev , et al. · 2022

Objective Maps of B0 field inhomogeneities are often used to improve MRI image quality, even in a retrospective fashion. These field inhomogeneities depend on the exact head position within the static field but acquiring field maps (FM) at…

Optimized ultrahigh field parallel transmission workflow using rapid presaturated TurboFLASH transmit field mapping with a three‐dimensional centric single‐shot readout Open

Dario Bosch, J Bause, Ole Geldschläger, Klaus Scheffler · 2022

Purpose To evaluate the usage of three‐dimensional (3D) presaturated TurboFLASH (satTFL) for and mapping on single channel and parallel transmission (pTx) systems. Methods maps recorded with 3D satTFL were compared to maps from three other…

Accelerated MRI at 9.4 T with electronically modulated time‐varying receive sensitivities Open

Felix Glang, Anton Nikulin, J Bause, Rahel Heule, Theodor Steffen , et al. · 2022

Purpose To investigate how electronically modulated time‐varying receive sensitivities can improve parallel imaging reconstruction at ultra‐high field. Methods Receive sensitivity modulation was achieved by introducing PIN diodes in the re…

Integration of visual motion and pursuit signals in areas V3A and V6+ across cortical depth using 9.4T fMRI Open

Fatemeh Molaei-Vaneghi, Natalia Zaretskaya, Tim van Mourik, J Bause, Klaus Scheffler , et al. · 2021

Neural mechanisms underlying a stable perception of the world during pursuit eye movements are not fully understood. Both, perceptual stability as well as perception of real (i.e. objective) motion are the product of integration between mo…

Bent folded‐end dipole head array for ultrahigh‐field MRI turns “dielectric resonance” from an enemy to a friend Open

Nikolai I. Avdievich, Georgiy Solomakha, Loreen Ruhm, J Bause, Klaus Scheffler , et al. · 2020

Purpose To provide transmit whole‐brain coverage at 9.4 T using an array with only eight elements and improve the specific absorption rate (SAR) performance, a novel dipole array was developed, constructed, and tested. Methods The array co…

Eye-selective fMRI activity in human primary visual cortex: Comparison between 3 T and 9.4 T, and effects across cortical depth Open

Natalia Zaretskaya, J Bause, Jon̈athan R. Polimeni, Pablo Rodrigo Grassi, Klaus Scheffler , et al. · 2020

Impact of prospective motion correction, distortion correction methods and large vein bias on the spatial accuracy of cortical laminar fMRI at 9.4 Tesla Open

J Bause, Jon̈athan R. Polimeni, Johannes Stelzer, Myung‐Ho In, Philipp Ehses , et al. · 2019

Functional imaging with sub-millimeter spatial resolution is a basic requirement for assessing functional MRI (fMRI) responses across different cortical depths and is used extensively in the emerging field of laminar fMRI. Such studies see…

Brainglance: Visualizing Group Level MRI Data at One Glance Open

Johannes Stelzer, Eric Lacosse, J Bause, Klaus Scheffler, Gabriele Lohmann · 2019

The vast majority of studies using functional magnetic resonance imaging (fMRI) are analyzed on the group level. Standard group-level analyses, however, come with severe drawbacks: First, they assume functional homogeneity within the group…

3D CEST MRI of human brain at 9.4T reveals vessel correlation of the effect at -1.7 ppm Open

Moritz Zaiß, J Bause, A Deshmane, Kai Herz, Klaus Scheffler · 2018

In vivo CEST imaging at 9.4T reveals that the peak at -1.7 ppm which was recently associated with red blood cells is spatially localized to blood vessels. A 3D CEST sequence with high resolution and dense sampling of the Z-spectrum shows t…

MRI of whole brain formalin-fixed samples at 9.4T: influence of the fixation agent and its dielectric properties on image quality Open

G Hagberg, T Shiozawa-Bayer, C Mirkes, J Engelmann, J Bause , et al. · 2018

MRI of post mortem samples in formalin is an essential tool for validation purposes and comparison with clinical histology, since fixation preserve several microstructural tissue features. We found that the dielectric properties of the fix…

In-vivo Quantitative Structural Imaging of the Superior Colliculus at 9.4T Open

Joana Loureiro, Marc Himmelbach, Thomas Ethofer, R Pohmann, Pascal Martin , et al. · 2018

We investigated the possibility to observe the anatomical details of the superior colliculus (SC), a layered structure located on the tectum of the midbrain, by in vivo MRI at 9.4T. Through image analysis in native space, several brain str…

Fast and efficient free induction decay MR spectroscopic imaging of the human brain at 9.4 Tesla Open

G Chadzynski, J Bause, G Shajan, R Pohmann, Klaus Scheffler , et al. · 2016

Purpose The purpose of this work was to develop a fast and efficient MRSI‐FID acquisition scheme and test its performance in vivo. The aim was to find a trade‐off between the minimal total acquisition time and signal‐to‐noise ratio of the …

Depth‐dependence of visual signals in the human superior colliculus at 9.4 T Open

Joana Loureiro, G Hagberg, Thomas Ethofer, Michael Erb, J Bause , et al. · 2016

The superior colliculus (SC) is a layered structure located in the midbrain. We exploited the improved spatial resolution and BOLD signal strength available at 9.4 T to investigate the depth profile of visual BOLD responses in the human SC…

Neural Control of Discrete and Rhythmic Movements Open

Eric Lacosse, J Bause, Gabriele Lohmann, Klaus Scheffler, Stefan Schaal , et al. · 2016

Fast and efficient free induction decay proton MRSI in the human brain at 9.4 T Open

GL Chadzynski, Klaus Scheffler, J Bause, G Shajan, R Pohmann , et al. · 2015

Purpose/Introduction: Free induction decay (FID) based MRSI has been shown to be highly promising at ultra-high magnetic field [1, 2]. It avoids in-plane chemical shift displacement and allows short echo time. However, the necessity to use…

Simulation of Flow-Driven Adiabatic Inversion in Dual Coil Continuous ASL at 9.4 T Open

J Bause, Klaus Scheffler, R Pohmann · 2015

Purpose/Introduction: Continuous ASL with labeling coils placed at the subject´s neck (DC-CASL, [1]) has a high sensitivity [2], does not suffer from magnetization transfer effects and leads to lower power deposition than any other CASL te…

Choice of RF coils at 9.4T: SNR and B1+ of transceiver and transmit-only receive-only arrays Open

G Shajan, J Bause, R Pohmann, Klaus Scheffler · 2015

Purpose/Introduction: Signal to noise ratio (SNR) and transmit efficiency are the most important considerations in RF coil design. Tight fitting transceiver (TxRx) arrays are often used to optimize the transmit efficiency [1], while large …

Quantitative and functional pulsed arterial spin labeling in the human brain at 9.4 t Open

J Bause, Philipp Ehses, C Mirkes, G Shajan, Klaus Scheffler , et al. · 2015

Purpose The feasibility of multislice pulsed arterial spin labeling (PASL) of the human brain at 9.4 T was investigated. To demonstrate the potential of arterial spin labeling (ASL) at this field strength, quantitative, functional, and hig…

Triple‐quantum‐filtered sodium imaging at 9.4 Tesla Open

C Mirkes, G Shajan, J Bause, Kai Buckenmaier, Jens Hoffmann , et al. · 2015

Purpose Efficient acquisition of triple‐quantum‐filtered (TQF) sodium images at ultra‐high field (UHF) strength. Methods A three‐pulse preparation and a stack of double‐spirals were used for the acquisition of TQF images at 9.4 Tesla. The …

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