Philippe Birmes
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View article: High Psychological Impact of Covid‐19 on French Healthcare Workers: An Observational Cohort Study of PTSD, Depression and Burn‐Out
High Psychological Impact of Covid‐19 on French Healthcare Workers: An Observational Cohort Study of PTSD, Depression and Burn‐Out Open
Introduction The Covid‐19 outbreak hit the world forcing public institutions to rethink their core functioning. Healthcare workers (HCWs) were particularly at risk for negative mental health outcomes, given their direct exposure to many pa…
View article: Severe PTSD or just PTSD?
Severe PTSD or just PTSD? Open
Although the widespread of trauma exposure, post-traumatic stress disorder (PTSD) remains a prevalent and disabling mental disorder. Yet, access to appropriate care, particularly for individuals with more severe forms, remains limited. The…
View article: Hippocampal connectivity changes after traumatic memory reactivation with propranolol for posttraumatic stress disorder: a randomized fMRI study
Hippocampal connectivity changes after traumatic memory reactivation with propranolol for posttraumatic stress disorder: a randomized fMRI study Open
Background: Reactivation of traumatic memory under the influence of propranolol has shown encouraging clinical results in the treatment of posttraumatic stress disorder (PTSD), but the neural correlates remain unknown. To identify these co…
View article: Specific properties changes of traumatic memory in PTSD patients after multiple reactivations of this memory under propranolol or placebo: An exploratory study
Specific properties changes of traumatic memory in PTSD patients after multiple reactivations of this memory under propranolol or placebo: An exploratory study Open
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View article: Effectiveness of psychiatric support for complicated grief among a cohort of relatives of deceased patients in intensive care unit during the French Covid-19 lockdown – the OLAF (Opération Liaison et Aide aux Familles)
Effectiveness of psychiatric support for complicated grief among a cohort of relatives of deceased patients in intensive care unit during the French Covid-19 lockdown – the OLAF (Opération Liaison et Aide aux Familles) Open
Introduction: The death of a relative after an intensive care unit stay can lead to mental disorders as post-traumatic stress disorder or complicated grief. During the first SARS-CoV-2 lockdown in France, social restrictions limited the op…
View article: Predictors of prospective suicide attempts in a group at risk of personality disorder following self-poisoning
Predictors of prospective suicide attempts in a group at risk of personality disorder following self-poisoning Open
Background Patients with personality disorder (PD) are at risk for suicidal behavior and are frequently admitted for this reason to emergency departments. In this context, researchers have tried to identify predictors of their suicidal act…
View article: Efficiency of a psychiatric support for PTSD on a cohort of relatives of patients hospitalized in intensive care unit during the French lockdown – the OLAF (Opération Liaison et Aide aux Familles in French) dispositive
Efficiency of a psychiatric support for PTSD on a cohort of relatives of patients hospitalized in intensive care unit during the French lockdown – the OLAF (Opération Liaison et Aide aux Familles in French) dispositive Open
Introduction Having a family member admitted in Intensive Care Unit (ICU) can cause a severe psychological stress, and various psychological disorders gathered into the notion of Post intensive care syndrome-family (PICS-F). In this way, F…
View article: EMDR for symptoms of depression, stress and burnout in health care workers exposed to COVID-19 (HARD): A study protocol for a trial within a cohort study
EMDR for symptoms of depression, stress and burnout in health care workers exposed to COVID-19 (HARD): A study protocol for a trial within a cohort study Open
Background: Stressful events during a pandemic are a major cause of serious health problems, such as burnout, depression and posttraumatic stress disorder (PTSD) among health care workers (HCWs). During three years, HCWs, on the frontline …
View article: Efficacy of traumatic memory reactivation with or without propranolol in PTSD with high dissociative experiences
Efficacy of traumatic memory reactivation with or without propranolol in PTSD with high dissociative experiences Open
Background: Post-traumatic stress disorder (PTSD) with dissociative symptoms is now a full-fledged subtype of this disorder. The dissociative subtype is associated with a greater number of psychiatric comorbidities. To date, the impact of …
View article: Prevalence and prediction of PTSD and depression in mothers of children surviving a motor vehicle crash
Prevalence and prediction of PTSD and depression in mothers of children surviving a motor vehicle crash Open
Introduction: Few studies have examined the psychopathological consequences for parents of children who were survivors of a motor vehicle crash (MVC). This study assessed the impact of dissociation and peritraumatic distress on the severit…
View article: Case Report: A Case of Valproic Acid-Induced Hyperammonemic Encephalopathy Associated With the Initiation of Lithium: A Re-duplicable Finding
Case Report: A Case of Valproic Acid-Induced Hyperammonemic Encephalopathy Associated With the Initiation of Lithium: A Re-duplicable Finding Open
Introduction Hyperammonemic encephalopathy (HAE) is a serious adverse effect of valproate semisodium, which is facilitated by the potential for drug interaction. However, despite frequent co-prescription of valproate semisodium and lithium…
View article: Efficacy of traumatic memory reactivation with or without propranolol in PTSD with high dissociative experiences
Efficacy of traumatic memory reactivation with or without propranolol in PTSD with high dissociative experiences Open
Background: Post-traumatic stress disorder (PTSD) with dissociative symptoms is now a full-fledged subtype of this disorder. The dissociative subtype is associated with a greater number of psychiatric comorbidities. To date, the impact of …
View article: Post-traumatic Stress Disorder With Flashbacks of an Old Childhood Memory Triggered by Right Temporal Lobe Epilepsy Surgery in Adulthood
Post-traumatic Stress Disorder With Flashbacks of an Old Childhood Memory Triggered by Right Temporal Lobe Epilepsy Surgery in Adulthood Open
this case indicates that PTSD may occur after temporal lobe epilepsy surgery and may specifically stem, as in this context, from the excision of part of the medial temporal lobe structures. Although rarely reported, PTSD may be undiagnosed…
View article: Posttraumatic Stress Disorder Symptoms in Lymphoma Patients: A Prospective Study
Posttraumatic Stress Disorder Symptoms in Lymphoma Patients: A Prospective Study Open
The cancer experience may be marked by repeat stressors and/or traumas. The aim of our study was to assess traumatic events in a group of patients diagnosed with lymphoma and to determine which of these contribute to the development of Pos…
View article: Improving the mental health system for trauma victims in France
Improving the mental health system for trauma victims in France Open
France has a rich history of exposure to large-scale traumas such as wars, disasters and terrorist attacks, and psychiatric teams specialized in emergency interventions for mass trauma have been created across the territory. However, no pu…
View article: Suicidal Ideation and Traumatic Exposure Should Not Be Neglected in Epileptic Patients: A Multidimensional Comparison of the Psychiatric Profile of Patients Suffering From Epilepsy and Patients Suffering From Psychogenic Nonepileptic Seizures
Suicidal Ideation and Traumatic Exposure Should Not Be Neglected in Epileptic Patients: A Multidimensional Comparison of the Psychiatric Profile of Patients Suffering From Epilepsy and Patients Suffering From Psychogenic Nonepileptic Seizures Open
Introduction: Patients with psychogenic nonepileptic seizures (PNESs) have often been exposed to traumatic events, which is a risk factor for suicidal behavior. This would suggest that the severity of suicidal ideation is greater in PNES t…
View article: Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment
Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment Open
Post-traumatic stress disorder (PTSD) is a common consequence of exposure to a life-threatening event. Currently, pharmacological treatments are limited by high rates of relapse, and novel treatment approaches are needed. We have recently …
View article: Effects of Propranolol, a β-noradrenergic Antagonist, on Memory Consolidation and Reconsolidation in Mice
Effects of Propranolol, a β-noradrenergic Antagonist, on Memory Consolidation and Reconsolidation in Mice Open
Memory reconsolidation impairment using the β-noradrenergic receptor blocker propranolol is a promising novel treatment avenue for patients suffering from pathogenic memories, such as post-traumatic stress disorder (PTSD). However, in orde…