Jean Bousquet
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View article: All change, 2025
All change, 2025 Open
View article: Otitis Media With Effusion (<scp>OME</scp>) and Eustachian Tube Dysfunction: The Role of Allergy and Immunity—An <scp>EAACI</scp> Position Paper
Otitis Media With Effusion (<span>OME</span>) and Eustachian Tube Dysfunction: The Role of Allergy and Immunity—An <span>EAACI</span> Position Paper Open
IgE‐mediated allergies play a significant role in respiratory diseases. Given the similar mucosal epithelium of the upper and lower respiratory tracts and their shared (patho)physiological immune responses, the “unified airways” concept vi…
View article: Clustering of intuitive eating and psychological health identifies subgroups associated with weight loss following semaglutide
Clustering of intuitive eating and psychological health identifies subgroups associated with weight loss following semaglutide Open
Objective Obesity management requires personalized approaches. Using data from the Aviitam platform in France, this study aimed to do the following: 1) explore psychological and behavioral patterns through clustering techniques; 2) validat…
View article: Factors that influence user adherence of the Mask‐air® application
Factors that influence user adherence of the Mask‐air® application Open
Background Monitoring adherence in chronic diseases remains a significant challenge. Allergic rhinitis (AR), one of the most common chronic conditions, serves as an excellent model for studying determinants of app use in monitoring adheren…
View article: Impact of Demographic and Clinical Subgroups in Google Trends Data: Infodemiology Case Study on Asthma Hospitalizations
Impact of Demographic and Clinical Subgroups in Google Trends Data: Infodemiology Case Study on Asthma Hospitalizations Open
Background Google Trends (GT) data have shown promising results as a complementary tool to classical surveillance approaches. However, GT data are not necessarily provided by a representative sample of patients and may be skewed toward dem…
View article: Contrasting levels of transcriptome-wide SNP diversity and adaptive molecular variation among conifers
Contrasting levels of transcriptome-wide SNP diversity and adaptive molecular variation among conifers Open
Adaptive convergence can arise when response to natural selection involves shared molecular or functional mechanisms among multiple taxa. Conifers are archaic species of ancient origin with delayed sexual maturity related to their woody pe…
View article: WAO - ARIA consensus on chronic cough: Executive summary
WAO - ARIA consensus on chronic cough: Executive summary Open
View article: Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study Open
Background Adherence to rhinitis treatment has been insufficiently assessed. We aimed to use data from the MASK‐air mHealth app to assess adherence to oral antihistamines (OAH), intra‐nasal corticosteroids (INCS) or azelastine‐fluticasone …
View article: Evaluation of recently proposed thresholds to define spirometry bronchodilator response
Evaluation of recently proposed thresholds to define spirometry bronchodilator response Open
The proposed ERS/ATS 2022 guidelines appear to underestimate the prevalence of spirometry response to bronchodilator and individuals not identified have higher respiratory burden, potentially leading to additional testing and delayed as…
View article: Determination of the Bioavailability of 3 Intranasal Formulations of Azelastine Hydrochloride in Healthy Male Volunteers
Determination of the Bioavailability of 3 Intranasal Formulations of Azelastine Hydrochloride in Healthy Male Volunteers Open
The primary objective of the study was to determine the bioavailability of 2 new formulations of azelastine (AZE) hydrochloride (0.10% and 0.15% AZE) containing sorbitol and sucralose compared with the commercially available 0.10% AZE. Thi…
View article: Roads to remission: evolving treatment concepts in type 2 inflammatory diseases
Roads to remission: evolving treatment concepts in type 2 inflammatory diseases Open
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View article: In perennial allergic rhinitis, RQLQ is improved similarly by Azelastine 0.15 and mometasone furoate
In perennial allergic rhinitis, RQLQ is improved similarly by Azelastine 0.15 and mometasone furoate Open
View article: Spruce hybrids show superior cumulative growth and intermediate response to climate anomalies, as compared to their ecologically divergent parental species
Spruce hybrids show superior cumulative growth and intermediate response to climate anomalies, as compared to their ecologically divergent parental species Open
Climate change brings new constraints to which trees will have to adapt, including more frequent weather extremes. Black spruce and red spruce are phylogenetically close but adapted to different ecological conditions, and they form a natur…
View article: Double-blind, placebo-controlled trial of the efficacy and safety of azelastine hydrochloride in children with perennial allergic rhinitis
Double-blind, placebo-controlled trial of the efficacy and safety of azelastine hydrochloride in children with perennial allergic rhinitis Open
Background: Allergic rhinitis (AR) affects up to 40% of the pediatric population. The US practice parameter recommends the use of INAH or INCS as first-line therapy for the treatment of AR. Although not directly targeted to children, the r…
View article: When patient-reported respiratory symptoms shed light on pathophysiology in adult asthma: a cross-sectional study
When patient-reported respiratory symptoms shed light on pathophysiology in adult asthma: a cross-sectional study Open
View article: Perceptions of the impact of individual allergic rhinitis symptoms: A survey of ARIA clinical experts
Perceptions of the impact of individual allergic rhinitis symptoms: A survey of ARIA clinical experts Open
View article: Assessment of the underreporting of rhinitis in patients with asthma: A MASK-air® real-world study
Assessment of the underreporting of rhinitis in patients with asthma: A MASK-air® real-world study Open
Rhinitis is a common comorbidity in patients with asthma. However, the frequency of underreported rhinitis in asthma is not known. In this study, we aimed to assess the characteristics of patients with self-reported asthma and no self-repo…
View article: Effects on Physical Functioning and Fear of Falling of a 3-Week Balneotherapy Program Alone or Associated with a Physical Activity and Educational Program in Older Adult Fallers: A Randomized-Controlled Trial
Effects on Physical Functioning and Fear of Falling of a 3-Week Balneotherapy Program Alone or Associated with a Physical Activity and Educational Program in Older Adult Fallers: A Randomized-Controlled Trial Open
Older patients referred to a balneotherapy program and at high risk of falling when screened at the entrance of the center should be offered an additional physical and educational program to further improve the functional effects of balneo…
View article: Impact of Allergic Rhinitis on Academic Performance in Adolescents and Adults: a Bayesian Analysis of MASK-air® Real-world Direct Patient Data
Impact of Allergic Rhinitis on Academic Performance in Adolescents and Adults: a Bayesian Analysis of MASK-air® Real-world Direct Patient Data Open
View article: Association between asthma and IgG levels specific for rhinovirus and respiratory syncytial virus antigens in children and adults
Association between asthma and IgG levels specific for rhinovirus and respiratory syncytial virus antigens in children and adults Open
View article: Concurrent validity, cut‐offs and ability to change of patient‐reported outcome measures for rhinitis and asthma in MASK‐air<sup>®</sup>
Concurrent validity, cut‐offs and ability to change of patient‐reported outcome measures for rhinitis and asthma in MASK‐air<sup>®</sup> Open
Patient‐reported outcome measures (PROMs) are used to assess a patient's health status at a particular point in time. They are essential in the development of person‐centred care. This paper reviews studies performed on PROMs for assessing…
View article: Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review
Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review Open
Published literature based on various parameters and clinical trials conducted for evaluating the effect of fexofenadine on sedation and central nervous system shows fexofenadine is both clinically effective and non-sedating.
View article: Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)
Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024) Open
View article: Impact of Uncontrolled Symptoms on the Health‐Related Quality of Life (<scp>EQ</scp>‐<scp>5D</scp>‐<scp>5L</scp>) of Patients With Allergic Rhinitis: A <scp>MASK</scp>‐air Study
Impact of Uncontrolled Symptoms on the Health‐Related Quality of Life (<span>EQ</span>‐<span>5D</span>‐<span>5L</span>) of Patients With Allergic Rhinitis: A <span>MASK</span>‐air Study Open
The impact of allergic rhinitis (AR) on patients' quality of life (QoL) may vary with disease control and comorbidities [1]. Previously, we quantified utilities for different levels of AR control but did not assess the impact of specific s…
View article: A meta-analysis on the effects of marker coverage, status number, and size of training set on predictive accuracy and heritability estimates from genomic selection in tree breeding
A meta-analysis on the effects of marker coverage, status number, and size of training set on predictive accuracy and heritability estimates from genomic selection in tree breeding Open
Genomic selection (GS) is increasingly used in tree breeding because of the possibility to hasten breeding cycles, increase selection intensity or facilitate multi-trait selection, and to obtain less biased estimates of quantitative geneti…
View article: Embedding patients' values and preferences in guideline development for allergic diseases: The case study of Allergic Rhinitis and its Impact on Asthma 2024
Embedding patients' values and preferences in guideline development for allergic diseases: The case study of Allergic Rhinitis and its Impact on Asthma 2024 Open
Recommendations for or against the use of interventions need to consider both desirable and undesirable effects as well as patients' values and preferences (V&P). In the decision‐making context, patients' V&P represent the relative importa…
View article: Relevance of individual bronchial symptoms for asthma diagnosis and control in patients with rhinitis: A MASK‐air study
Relevance of individual bronchial symptoms for asthma diagnosis and control in patients with rhinitis: A MASK‐air study Open
Rationale It is unclear how each individual asthma symptom is associated with asthma diagnosis or control. Objectives To assess the performance of individual asthma symptoms in the identification of patients with asthma and their associati…
View article: Contribution of MASK-air® as an mHealth Tool for Digitally Enabled Person-Centered Care in Rhinitis and Asthma
Contribution of MASK-air® as an mHealth Tool for Digitally Enabled Person-Centered Care in Rhinitis and Asthma Open
In chronic diseases, mHealth apps help to improve clinical management and provide valuable real-world scientific evidence. In allergic rhinitis, a market research study identified only 4 mHealth apps that were multilingual, resulted in sci…
View article: Digitally‐enabled, person‐centred care (PCC) in allergen immunotherapy: An ARIA‐EAACI Position Paper
Digitally‐enabled, person‐centred care (PCC) in allergen immunotherapy: An ARIA‐EAACI Position Paper Open
In rhinitis and asthma, several mHealth apps have been developed but only a few have been validated. However, these apps have a high potential for improving person‐centred care (PCC), especially in allergen immunotherapy (AIT). They can pr…
View article: Factors Affecting Usage of a Digital Asthma Monitoring Application by Old-Age Asthmatics Living in Inner Central Portugal
Factors Affecting Usage of a Digital Asthma Monitoring Application by Old-Age Asthmatics Living in Inner Central Portugal Open
Most old-age asthmatics living in Beira Interior either lack a smartphone or digital skills, which are significant obstacles to implementing app-based monitoring studies.