Explanipedia

Cortical asymmetry in autosomal dominant Alzheimer’s disease progression Open

Agnès Pérez-Millan, Neus Falgàs, Beatriz Muries Bosch, Sergi Borrego-Écija, Anna Antonell , et al. · 2025

Medicine Psychology

The cortical asymmetry index evaluates the cortical thickness asymmetry between hemispheres. We investigated cortical asymmetry index in asymptomatic and symptomatic mutation carriers of autosomal dominant Alzheimer’s disease to explore th…

Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison Open

Jennifer W. Robinette, Jacqui Smith · 2025

Psychology Geography

In the US, racial/ethnic health disparities are undeniable and partially stem from residing in low SES neighborhoods. Associations between neighborhood SES and health may have some underlying molecular mechanisms reflected in the epigenome…

Accelerated Molecular Aging in Neighborhood Poverty: A Racial/Ethnic Comparison Open

Jennifer W. Robinette, Jacqui Smith · 2025

Psychology Geography

In the US, racial/ethnic health disparities are undeniable and partially stem from residing in low SES neighborhoods. Associations between neighborhood SES and health may have some underlying molecular mechanisms reflected in the epigenome…

LATE-LIFE SINGLEHOOD AND WELL-BEING: THE ROLE OF MARITAL STATUS AND SOCIAL RESOURCES Open

Urmimala Ghose, Rinseo Park, Jacqui Smith, Nilàm Ram, Denis Gerstorf · 2024

Psychology Medicine

Singlehood has long been identified as a potential risk factor for undermining well-being across adulthood, particularly in older ages. However, it is an open question what role other social resources may play. In the current study, we exa…

COLLEGE EDUCATION AND LEISURE ACTIVITIES PREDICT LATE-LIFE COGNITIVE STATUS: DO BIRTH COHORTS DIFFER? Open

Jacqui Smith, Kimson Johnson, Marina Larkina · 2024

Psychology Medicine Sociology

Efforts to determine potentially modifiable factors associated with heterogeneity in cognitive status in old age point to the importance of participation in cognitive, physical, and social leisure activities and the relevance of historical…

LATE-LIFE OUTCOMES OF FEELINGS OF BELONGING THROUGHOUT THE LIFE COURSE Open

Emily Briggs, Jacqui Smith · 2024

Psychology Engineering

Belonging is a fundamental human need that encourages fortitude throughout the life course. In the literature, belonging has been studied primarily from two perspectives: place attachment (Chawla, 1992, Scannell, 2021) and belonging within…

ARE LIFE ACCOMPLISHMENTS RELATED TO WELL-BEING: FINDINGS FROM THE HEALTH AND RETIREMENT STUDY (HRS)? Open

Marina Larkina, Jacqui Smith · 2024

Psychology Medicine

Butler (1963) proposed that engaging in a whole life review is especially beneficial for older adults because it promotes a sense of self-worth. Previous research highlights links between reminiscing and psychological well-being, however, …

MEMORY ISSUES IN RETROSPECTIVE LIFE HISTORY SURVEYS: DO QUESTION TYPE AND TOPIC MATTER? Open

Wenqing Qian, Wenshan Yu, Mary Beth Ofstedal, Jacqui Smith, Marina Larkina , et al. · 2024

History Computer science

Collecting retrospective information from the older population is critical yet challenging, and especially in self-administered surveys. Older adults may have difficulty retrieving autobiographical memories, navigating skip patterns in mai…

HEALTH RESILIENCE AND FORTITUDE FACTORS IN THE HRS Open

Rebecca Allen, Jacqui Smith · 2024

Psychology Medicine Materials science

This symposium presents data from recent waves of the Health and Retirement Study, a nationally representative sample of older adults in the United States, examining environmental transition and health variables as they relate to fortitude…

LIFETIME PATTERNS OF EXPOSURE TO JOB COMPLEXITY AND LATER LIFE COGNITION Open

Qize Chen, Joanne W. Hsu, Yun taek Oh, Jacqui Smith, Amanda Sonnega · 2024

Psychology

A growing body of evidence establishes a positive connection between cognitively engaging activities and later life cognitive functioning. Cognitively stimulating work—jobs that involve complex tasks and demands—is gaining increased resear…

Interpersonal, Community, and Societal Stressors Mediate Black–White Memory Disparities Open

Emily P. Morris, Jordan D Palms, Kiana A. Scambray, Ji Hyun Lee, Ketlyne Sol , et al. · 2024

Psychology Chemistry

Objectives Structural racism creates contextual stressors that disproportionately affect Black, relative to White, older adults in the United States and may contribute to worse cognitive health. We examined the extent to which interpersona…

Can Retrospective Reports Provide Accurate Job History Information? A Comparison With Concurrent Reports in a National Prospective Study of Older Adults Open

Amanda Sonnega, Maymona Al-Hinai, Qize Chen, Brooke Helppie‐McFall, Jacqui Smith · 2024

Psychology Medicine Political science

Background and Objectives The growing interest in the impact of lifetime occupational exposures on later-life health underscores the need to expand and evaluate the quality of data resources. The present study took advantage of a retrospec…

PRESIDENTIAL SYMPOSIUM: HIGHLIGHTING EMERGING PROFESSIONALS WHO BUILD BRIDGES, CATALYZE RESEARCH, AND EMPOWER ALL AGES Open

Brianna Morgan, Rita Xiaochen Hu, Jacqui Smith · 2023

Political science Sociology History

There are many ways to carve a path forward in aging research, policy, and practice. Sometimes the career possibilities are overwhelming, leaving us unsure of how best to proceed. As aging professionals, we know that there is much to learn…

HISTORICAL CHANGES IN COLLEGE EDUCATION AND EMPLOYMENT: GENDER EFFECTS ON LATE-LIFE COGNITIVE STATUS Open

Marina Larkina, Jacqui Smith · 2023

Psychology Medicine Sociology

Early-life education and gender are well-known predictors of cognitive status in old age but multiple mechanisms underlie these associations. Recent US research on late-life cognition and dementia prevalence has highlighted the roles of ag…

CONTACT FREQUENCY WITH CHILDREN FOLLOWING RELOCATION LATER IN LIFE: DO CONTACT MODES AND PROXIMITY TO A CHILD MATTER? Open

Joonyoung Cho, Ruth E. Dunkle, Jacqui Smith · 2023

Psychology Medicine Sociology

Contact with children is an important source of support for older adults. It is not clear if relocation and proximity to a child affect in-person communication as well as telephone, email, and social media contact between older parents and…

EFFECTS OF SELF-PERCEPTIONS OF AGING ON COGNITIVE HEALTH: MEDIATING ROLE OF SOCIAL ISOLATION AND LONELINESS Open

Rita Xiaochen Hu, Lydia Li, Toni C. Antonucci, Ruth E. Dunkle, Jacqui Smith , et al. · 2023

Psychology Medicine

Cognitive decline is one of the most common age-related stereotypes. The stereotype embodiment theory suggests that negative age stereotypes can be internalized through socialization and become negative self-perceptions of aging (SPA). How…

Early learning difficulties, childhood stress, race, and risk of cognitive impairment among US adults over age 50: A cross‐sectional analysis Open

Allan Nkwata, Jacqui Smith · 2023

Psychology Medicine

Background and Aims Most literature linking childhood factors to cognitive health outcomes has focused on educational attainment—defined as years of education attained. However, less has been studied about the other aspects of education, s…

THE EARLY LIFE CONTEXTS OF THE HEALTH AND RETIREMENT STUDY HCAP SAMPLE: NEW INSIGHTS INTO DEMENTIA RISK FACTORS Open

Jacqui Smith, Marina Larkina, Wenshan Yu · 2023

Psychology Medicine

There’s increasing interest in identifying potentially modifiable early-life socioenvironmental factors associated with late-life cognitive decline and dementia. To date, much research points to the importance of the number of years spent …

FEELING YOU BELONG: THE EFFECTS OF COMMUNITY INVOLVEMENT ON WELL-BEING IN LATER LIFE Open

Emily Briggs, Jacqui Smith · 2023

Psychology Medicine Sociology

The area where someone lives is an important, yet neglected, contextual factor for the health of older adults. Previous literature suggests that an individual may develop an attachment to their neighborhood through a feeling of “rootedness…

EARLY LIFE LEARNING DISABILITY, PREMATURE PARENTAL DEATH PREDICTS LATE LIFE COGNITIVE IMPAIRMENT Open

Allan Nkwata, Jacqui Smith · 2023

Psychology Medicine Mathematics

Recent studies have increasingly identified links between early learning difficulties and later life cognitive impairment. Additionally, the death of a parent adversely affects various outcomes across the life course, particularly when the…

INTERPERSONAL, COMMUNITY, AND SOCIETAL STRESSORS MEDIATE BLACK–WHITE MEMORY DISPARITIES Open

Emily P. Morris, Jordan D Palms, Ji Hyun Lee, Ketlyne Sol, Kiana A. Scambray , et al. · 2023

Psychology Medicine Sociology

Psychosocial factors may contribute to racial disparities in cognitive aging beyond socioeconomic status. Contextual stressors at multiple ecological levels, which may be related to structural racism, disproportionately affect Black older …

Post‐secondary Education as a Modifiable Risk for Dementia: Birth Cohort and Gender Findings from the Health and Retirement Study Open

Jacqui Smith, Marina Larkina, Amanda Sonnega · 2023

Medicine Psychology Sociology

Background Education and gender are well‐known predictors of cognitive functioning after age 60, but multiple mechanisms underlie these associations. Research on dementia prevalence in the United States has highlighted the importance of co…

The Impact of Caregiving History on Later-Life Self-Perceptions of Aging Open

Rita Xiaochen Hu, Marina Larkina, Jacqui Smith · 2023

Psychology Medicine

Objectives Theories suggest that self-perceptions of aging (SPA) reflect structural and cultural ageism together with an individual’s personal life experiences. We examine the impact of an individual’s history of informal caregiving on the…

Changes in childhood caregiving impressions among middle‐aged and older adults Open

William J. Chopik, Jeewon Oh, Sneha Challa, Hannah L. Hua, Julia M. Maahs , et al. · 2023

Psychology

Childhood experiences and impressions are important for individuals' health and well‐being—they often set the stage for how people approach relationships across the lifespan and how they make sense of their relational worlds. However, impr…

Life course engagement in enriching activities: When and how does it matter for cognitive aging? Open

Colleen C Frank, Lindsey M Mundy, Jacqui Smith · 2023

Psychology Medicine Political science

Growing evidence suggests that participation in enriching activities (physical, social, and mental) across the life course is beneficial for cognitive functioning in older age. However, few studies have examined the effects of enrichment a…

SELF-PERCEPTIONS OF AGING IN THE CONTEXT OF CHALLENGING EXPERIENCES: PATTERNS OF RISK AND RESILIENCE Open

Hannah L. Giasson, Rachel Koffer, Jacqui Smith · 2022

Psychology Medicine Biology

Self-perceptions of aging have important implications for health and well-being in later life. Early life experiences, cultural and societal notions about age, and one’s present health and situational context may contribute to one’s expect…

INVESTIGATING LINKS BETWEEN CHILDHOOD HEALTH AND FAMILY LIFE AND ACCELERATED BIOLOGICAL AGING Open

Marina Larkina, Jacqui Smith · 2022

Medicine Biology Sociology

An epigenetic clock measure, DNA methylation (DNAm) PhenoAge, differentiates individual aging trajectories and has been shown to predict mortality and morbidities. Despite suggestions that early-life experiences may shape epigenetic aging,…

EARLY-LIFE EDUCATION AND COGNITIVE AGING: DOES CONTENT, LOCATION, AND HISTORICAL CONTEXT MATTER? Open

Jacqui Smith, Laura B. Zahodne · 2022

Psychology Sociology Medicine

Life course and cognitive aging theories about the sources of subgroup and individual differences in susceptibility to cognitive impairment frequently highlight the significance of early-life education, defined in research by total years o…

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