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View article: Genetic landscape of non‐ <scp>UV</scp> ‐induced cutaneous squamous cell carcinomas
Genetic landscape of non‐ <span>UV</span> ‐induced cutaneous squamous cell carcinomas Open
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer and is most often caused by cumulative UV exposure. However, cSCC may also arise independently of UV exposure, on sites of sustained skin damage like chronic ul…
View article: A multicentre pragmatic randomized controlled trial comparing 50% salicylic acid, liquid nitrogen, 5% 5-fluorouracil cream, and 5% imiquimod cream in previously treated plantar warts. The VRAIE (VeRrues plAntaIres en villE) study
A multicentre pragmatic randomized controlled trial comparing 50% salicylic acid, liquid nitrogen, 5% 5-fluorouracil cream, and 5% imiquimod cream in previously treated plantar warts. The VRAIE (VeRrues plAntaIres en villE) study Open
While the trial failed to enrol the planned number of patients, the study showed that no treatment had a substantial positive effect as second-line treatment of plantar warts.
View article: Early neurosyphilis with serofast state
Early neurosyphilis with serofast state Open
We report a rare case of confirmed early neurosyphilis with serofast state in HIV-negative patient, with uncontrolled type 2 diabetes mellitus. Syphilitic meningitis was diagnosed initially on serology and cerebrospinal fluid (CSF) analysi…
View article: FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice Open
View article: Screening for precancerous anal lesions linked to human papillomaviruses: French recommendations for clinical practice
Screening for precancerous anal lesions linked to human papillomaviruses: French recommendations for clinical practice Open
View article: HPV vaccination practices among organ transplant recipients in France
HPV vaccination practices among organ transplant recipients in France Open
View article: Supplementary Figure 4 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 4 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 437K, Characterization of the M-LN CD56bright CD16+ and CD16- NK cell subsets.
View article: Supplementary Figure 3 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 3 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 339K, Phenotype of M-LN NK cells in function of the disease stage.
View article: Supplementary Figure 1 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 1 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 272K, Gating strategy of NK cells in total LN cell suspensions.
View article: Data from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Data from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
Melanomas are characterized by high metastatic potential, with regional lymph node representing the most frequent site of early dissemination in this disease. These regional lymph nodes also represent the primary site for differentiation o…
View article: Supplementary Figure 2 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 2 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 167K, Analyses of CD4+ Foxp3 Tregs in LN cell suspensions.
View article: Data from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Data from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
Melanomas are characterized by high metastatic potential, with regional lymph node representing the most frequent site of early dissemination in this disease. These regional lymph nodes also represent the primary site for differentiation o…
View article: Supplementary Figure 2 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 2 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 167K, Analyses of CD4+ Foxp3 Tregs in LN cell suspensions.
View article: Supplementary Figure 5 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 5 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 450K, Phenotype of blood NK cells from stage III melanoma patients.
View article: Supplementary Figure 6 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 6 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 359K, NK cell mediated lysis determined by dynamic measure of cell index of adherent melanoma targets.
View article: Supplementary Figure 3 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 3 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 339K, Phenotype of M-LN NK cells in function of the disease stage.
View article: Supplementary Figure 1 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 1 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 272K, Gating strategy of NK cells in total LN cell suspensions.
View article: Supplementary Figure 6 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 6 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 359K, NK cell mediated lysis determined by dynamic measure of cell index of adherent melanoma targets.
View article: Supplementary Figure 5 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 5 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 450K, Phenotype of blood NK cells from stage III melanoma patients.
View article: Supplementary Figure 4 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Supplementary Figure 4 from Mature Cytotoxic CD56<sup>bright</sup>/CD16<i><sup>+</sup></i> Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma Open
PDF file - 437K, Characterization of the M-LN CD56bright CD16+ and CD16- NK cell subsets.
View article: Surveillance of Antibiotic Resistance Genes in Treponema Pallidum Subspecies Pallidum from Patients with Early Syphilis in France
Surveillance of Antibiotic Resistance Genes in Treponema Pallidum Subspecies Pallidum from Patients with Early Syphilis in France Open
Benzathine penicillin G (BPG) is the reference treatment for early syphilis, but shortages have recently been reported, highlighting a need for the validation of alternative treatments. The aim of this study was to evaluate the genomic res…
View article: Supplementary Material for: Pembrolizumab for Unresectable or Metastatic Melanoma in Patients Older than 85 Years of Age
Supplementary Material for: Pembrolizumab for Unresectable or Metastatic Melanoma in Patients Older than 85 Years of Age Open
Background: Programmed cell death protein-1 (PD-1) inhibitors (pembrolizumab and nivolumab) have been approved for the treatment of advanced melanoma. Over the past decades, patients older than 85 years represent an expanding…
View article: Characteristics and Management of IgA Vasculitis (Henoch‐Schönlein) in Adults: Data From 260 Patients Included in a French Multicenter Retrospective Survey
Characteristics and Management of IgA Vasculitis (Henoch‐Schönlein) in Adults: Data From 260 Patients Included in a French Multicenter Retrospective Survey Open
Objective Data on adult IgA vasculitis (Henoch‐Schönlein) (IgAV) are scarce. This survey was designed to better define the clinical spectrum of IgAV and efficacy of treatments in a French patient population. Methods Data on clinical charac…
View article: Erratum to: Sarcopenic overweight is associated with early acute limiting toxicity of anti-PD1 checkpoint inhibitors in melanoma patients
Erratum to: Sarcopenic overweight is associated with early acute limiting toxicity of anti-PD1 checkpoint inhibitors in melanoma patients Open
View article: Sarcopenia associated with a body mass index (BMI) > 25 kg/m2 predicts severe acute toxicity of nivolumab and pembrolizumab in melanoma patients
Sarcopenia associated with a body mass index (BMI) > 25 kg/m2 predicts severe acute toxicity of nivolumab and pembrolizumab in melanoma patients Open
View article: Slow natural history predicts higher response rate to nivolumab and pembrolizumab in advanced melanoma patients
Slow natural history predicts higher response rate to nivolumab and pembrolizumab in advanced melanoma patients Open
View article: Periostitis in secondary syphilis with prozone phenomenon
Periostitis in secondary syphilis with prozone phenomenon Open
View article: NKp30 isoforms and NKp46 transcripts in metastatic melanoma patients: Unique NKp30 pattern in rare melanoma patients with favorable evolution
NKp30 isoforms and NKp46 transcripts in metastatic melanoma patients: Unique NKp30 pattern in rare melanoma patients with favorable evolution Open
Given the NK cell-based immunosurveillance of melanoma, we investigated the prognostic value of NKp46 transcript and NKp30 isoform (NKp30A, NKp30B and NKp30C) profiling in blood of 187 melanoma patients including 13 long survivors (LS), me…
View article: Merkel cell carcinoma: value of sentinel lymph-node status and adjuvant radiation therapy
Merkel cell carcinoma: value of sentinel lymph-node status and adjuvant radiation therapy Open
View article: Characterization of the Microenvironment in Positive and Negative Sentinel Lymph Nodes from Melanoma Patients
Characterization of the Microenvironment in Positive and Negative Sentinel Lymph Nodes from Melanoma Patients Open
Melanomas are aggressive skin tumors characterized by high metastatic potential. Our previous results indicate that Natural Killer (NK) cells may control growth of melanoma. The main defect of blood NK cells was a decreased expression of a…