J. Darréon
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View article: Respiratory motion management for external radiotherapy: 2025 update
Respiratory motion management for external radiotherapy: 2025 update Open
Respiratory motion significantly impacts the precision of radiotherapy for thoracic and abdominal tumours. This article updates a prior review on respiratory management in radiotherapy, focusing on emerging technologies and clinical implem…
View article: The LRP4/YAP axis drives the radiation-tolerant persister (RTP) cell state in breast cancer
The LRP4/YAP axis drives the radiation-tolerant persister (RTP) cell state in breast cancer Open
Rationale: Breast cancer recurrences and treatment failures can be attributed to intra-tumoral heterogeneity (ITH), which is characterize by the coexistence of diverse cellular states, including cancer stem cells (CSCs), within a single tu…
View article: Cerenkov free micro-dosimetry in small-field radiation therapy technique
Cerenkov free micro-dosimetry in small-field radiation therapy technique Open
Objective . Optical fiber-based scintillating dosimetry is a recent promising technique owing to the miniature size dosimeter and quality measurement in modern radiation therapy treatment. Despite several advantages, the major issue of usi…
View article: Geometrical Characterization of an Inorganic Scintillator Detector for Proton Therapy Using a Micrometer-Scale Ion Beam
Geometrical Characterization of an Inorganic Scintillator Detector for Proton Therapy Using a Micrometer-Scale Ion Beam Open
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View article: Does Breast Surgery Type Alter Incidental Axillary Irradiation? A Dosimetric Analysis of the “Sentinel Envahi et Randomisation du Curage” SERC Trial
Does Breast Surgery Type Alter Incidental Axillary Irradiation? A Dosimetric Analysis of the “Sentinel Envahi et Randomisation du Curage” SERC Trial Open
Background. An incidental axillary dose of adjuvant radiotherapy using tangential beams is usually given after breast-conserving surgery for breast cancer. The goal of this sub-study was to evaluate this incidental dose in the setting of p…
View article: A novel lung SBRT treatment planning: Inverse VMAT plan with leaf motion limitation to ensure the irradiation reproducibility of a moving target
A novel lung SBRT treatment planning: Inverse VMAT plan with leaf motion limitation to ensure the irradiation reproducibility of a moving target Open
This study exposed the implementation of a novel technique (VMATLSL) for the planning of moving targets in lung stereotactic body radiation therapy (SBRT). This new technique has been compared to static conformal radiotherapy (3D-CRT), vol…
View article: Is MRI-Linac helpful in SABR treatments for liver cancer?
Is MRI-Linac helpful in SABR treatments for liver cancer? Open
Objective To determine the MRI-Linac added value over conventional image-guided radiation therapy (IGRT) in liver tumors Stereotactic ablative radiation therapy (SABR). Materials and methods We retrospectively compared the Planning Target …
View article: Is MRI-Linac helpful in SABR treatments for liver metastases?
Is MRI-Linac helpful in SABR treatments for liver metastases? Open
Objective To determine the MRI-Linac added value over conventional image-guided radiation therapy (IGRT) in liver tumors Stereotactic ablative radiation therapy (SABR). Materials and methods We retrospectively compared the Planning Target …
View article: Repeated Multimodality Ablative Therapies for Oligorecurrent Pulmonary Metastatic Disease
Repeated Multimodality Ablative Therapies for Oligorecurrent Pulmonary Metastatic Disease Open
Stereotactic body radiotherapy (SBRT) and percutaneous thermal ablation (TA) are alternatives to surgery for the management of pulmonary oligometastases. In this collaborative work, we retrospectively analyzed patients who had undergone it…
View article: Dosimetric characterization of a small-scale (Zn,Cd)S:Ag inorganic scintillating detector to be used in radiotherapy
Dosimetric characterization of a small-scale (Zn,Cd)S:Ag inorganic scintillating detector to be used in radiotherapy Open
All the results presented here anticipated that the developed detector can accurately measure delivered dose to the region of interest, claim accurate depth dose distribution hence it can be a suitable candidate for beam characterization a…
View article: High resolution small‐scale inorganic scintillator detector: HDR brachytherapy application
High resolution small‐scale inorganic scintillator detector: HDR brachytherapy application Open
Purpose Brachytherapy (BT) deals with high gradient internal dose irradiation made up of a complex system where the source is placed nearby the tumor to destroy cancerous cells. A primary concern of clinical safety in BT is quality assuran…
View article: Impact of fiducial markers placements on the delineation of target volumes in radiation therapy for oesophageal cancer: final results of the FIDUCOR study
Impact of fiducial markers placements on the delineation of target volumes in radiation therapy for oesophageal cancer: final results of the FIDUCOR study Open
Purpose This prospective monocentric phase II study (FIDUCOR-study) aimed at the assessment of the impact of fiducial markers (FMs) implantation on conformal chemo-radiation therapy (CRT) planning in esophageal carcinoma (EC) patients. Met…
View article: High spatial resolution inorganic scintillator detector for high‐energy X‐ray beam at small field irradiation
High spatial resolution inorganic scintillator detector for high‐energy X‐ray beam at small field irradiation Open
Purpose Small field dosimetry for radiotherapy is one of the major challenges due to the size of most dosimeters, for example, sufficient spatial resolution, accurate dose distribution and energy dependency of the detector. In this context…
View article: Safety and benefit of using a virtual bolus during treatment planning for breast cancer treated with arc therapy
Safety and benefit of using a virtual bolus during treatment planning for breast cancer treated with arc therapy Open
Purpose This study evaluates the benefit of a virtual bolus method for volumetric modulated arc therapy (VMAT) plan optimization to compensate breast modifications that may occur during breast treatment. Methods Ten files were replanned wi…
View article: Early PET-CT After Stereotactic Radiotherapy for Stage 1 Non-small Cell Lung Carcinoma Is Predictive of Local Control
Early PET-CT After Stereotactic Radiotherapy for Stage 1 Non-small Cell Lung Carcinoma Is Predictive of Local Control Open
Early PET response appears to correlate with local control at 1 year post SBRT.
View article: Comparison of Automated Atlas-Based Segmentation Software for Postoperative Prostate Cancer Radiotherapy
Comparison of Automated Atlas-Based Segmentation Software for Postoperative Prostate Cancer Radiotherapy Open
Automated atlas-based segmentation (ABS) algorithms present the potential to reduce the variability in volume delineation. Several vendors offer software that are mainly used for cranial, head and neck, and prostate cases. The present stud…