J E J Krige
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View article: Professor Jan H Louw: South Africa’s paediatric surgery pioneer
Professor Jan H Louw: South Africa’s paediatric surgery pioneer Open
Prof. Jan Hendrik Louw (1915 - 1992) was a pioneering figure in paediatric and adult surgery in South Africa, and he left an indelible mark on teaching, training, research and academia. He excelled academically and graduated from the Unive…
View article: Healthcare Disparities in the Treatment and Outcomes of Hepatocellular Carcinoma in South Africa
Healthcare Disparities in the Treatment and Outcomes of Hepatocellular Carcinoma in South Africa Open
Background The impact of healthcare disparities on the outcomes for hepatocellular carcinoma (HCC) has not been explored in South Africa. This study aims to evaluate and compare the presentation, treatment, and outcomes of HCC in a cohort …
View article: Resection and reconstruction in high-grade pancreatic head injuries
Resection and reconstruction in high-grade pancreatic head injuries Open
This study by Chui et al adds further important evidence in the treatment of high-grade pancreatic injuries and endorses the concept of the model of pancreatic trauma care designed to optimize treatment, minimize morbidity and enhance surv…
View article: Intermediate and long-term survival prediction using prognostic scores in patients undergoing salvage TIPS for uncontrolled variceal bleeding
Intermediate and long-term survival prediction using prognostic scores in patients undergoing salvage TIPS for uncontrolled variceal bleeding Open
Although sTIPS controlled variceal bleeding in 94% of patients after failed endoscopic therapy, in-hospital mortality was 29% and less than one quarter were alive after five years. The selected cut-off values for the nominated scoring syst…
View article: Does the textbook outcome in pancreatic surgery score after pancreaticoduodenectomy for ampullary carcinoma have prognostic value?
Does the textbook outcome in pancreatic surgery score after pancreaticoduodenectomy for ampullary carcinoma have prognostic value? Open
This study confirmed the value of TOPS as a useful measurement to assess hospital quality metrics and short-term survival after PD for AAV. One quarter of patients developed a major complication with a 6.3% FTR.
View article: Inflammatory myofibroblastic tumours of the liver – a systematic review
Inflammatory myofibroblastic tumours of the liver – a systematic review Open
HIMT is a disease more often affecting middle-aged males. The lesions are typically solitary with low recurrence after treatment. The relative roles of surgical versus medical treatment remain unclear. Differences in clinical presentation,…
View article: Pancreaticoduodenectomy for distal cholangiocarcinoma at a South African centre
Pancreaticoduodenectomy for distal cholangiocarcinoma at a South African centre Open
This is the first study detailing the management and outcomes of dCCA from sub-Saharan Africa (SSA). Despite the complete resection of dCCA, the prognosis is poor, and the long-term survival rate in our study is equivalent to that reported…
View article: Effect of preoperative biliary drainage on intraoperative biliary cultures and surgical outcomes after pancreatic resection
Effect of preoperative biliary drainage on intraoperative biliary cultures and surgical outcomes after pancreatic resection Open
POBD was associated with a high incidence of resistant organisms on the IBCs, a high incidence of surgical site infections and a high correlation between cultures from the surgical site infection and the IBCs.
View article: Outcomes of jaundice in advanced hepatocellular carcinoma – a sub-Saharan perspective
Outcomes of jaundice in advanced hepatocellular carcinoma – a sub-Saharan perspective Open
Jaundice is a marker of advanced disease and poor outcomes in hepatocellular carcinoma (HCC). The aim of this study was to describe and analyse the management and outcomes of jaundiced HCC patients at a large academic referral centre in su…
View article: Factors influencing in-hospital mortality for salvage percutaneous transjugular intrahepatic portosystemic shunting in cirrhotic patients with recalcitrant variceal bleeding after failed endoscopic intervention
Factors influencing in-hospital mortality for salvage percutaneous transjugular intrahepatic portosystemic shunting in cirrhotic patients with recalcitrant variceal bleeding after failed endoscopic intervention Open
Background. Endoscopic therapy is the first-line treatment of choice for control of acute variceal bleeding (AVB). In high-risk patients with persistent AVB despite pharmacological treatment and endoscopic intervention, percutaneous transj…
View article: The management and outcomes of hepatocellular carcinoma in sub-Saharan Africa: a systematic review
The management and outcomes of hepatocellular carcinoma in sub-Saharan Africa: a systematic review Open
The majority of SSA countries do not have data reporting outcomes for HCC. Most patients receive only BSC, and curative treatment is seldom available in the region. Outcomes are poor compared to high-income countries.
View article: Novel CABIN score outperforms other prognostic models in predicting in-hospital mortality after salvage transjugular intrahepatic portosystemic shunting
Novel CABIN score outperforms other prognostic models in predicting in-hospital mortality after salvage transjugular intrahepatic portosystemic shunting Open
The novel CABIN score had the best prediction capability with statistical superiority over seven other risk scores. Despite sTIPS, hospital mortality remains high and can be predicted by CABIN category B or C or CABIN scores > 10. Survival…
View article: Applying refined pancreaticogastrostomy techniques in pancreatic trauma
Applying refined pancreaticogastrostomy techniques in pancreatic trauma Open
We comment on a study titled "Feasibility and safety of "bridging" pancreaticogastrostomy for pancreatic trauma in Landrace pigs" in which ten pigs were randomized to either experimental "bridging" pancreaticogastrostomy (PG) or a control …
View article: Charles F M Saint – South Africa’s original surgical pioneer
Charles F M Saint – South Africa’s original surgical pioneer Open
Charles F M Saint, a 33-year-old graduate from the University of Durham, Newcastle upon Tyne, was appointed to establish the first department of surgery in South Africa (SA) at the University of Cape Town (UCT) in 1920. A mentee of the cel…
View article: Mentorship during undergraduate surgical training: comparing perceptions of medical students and faculty at two institutions in South Africa and Sweden
Mentorship during undergraduate surgical training: comparing perceptions of medical students and faculty at two institutions in South Africa and Sweden Open
BACKGROUND: Having a mentor during undergraduate surgical training has been shown to positively influence medical students by increasing interest in surgery, improving confidence, and assisting in career planning. This study aimed to evalu…
View article: Balloon tube tamponade for variceal bleeding: ten rules for safe usage
Balloon tube tamponade for variceal bleeding: ten rules for safe usage Open
Keywords: oesophageal variceal bleeding, Sengstaken-Blakemore tube, balloon tamponade
View article: Translation and linguistic validation of the EORTC QLQ-PAN26 questionnaire for assessment of health-related quality of life in patients with pancreatic cancer and chronic pancreatitis into isiXhosa and Afrikaans
Translation and linguistic validation of the EORTC QLQ-PAN26 questionnaire for assessment of health-related quality of life in patients with pancreatic cancer and chronic pancreatitis into isiXhosa and Afrikaans Open
BACKGROUND: Health-related quality of life (HRQOL) parameters have become important components in the holistic management of pancreatic ductal adenocarcinoma (PDAC) and are now increasingly incorporated in treatment protocols. The European…
View article: Defining the advantages and exposing the limitations of endoscopic variceal ligation in controlling acute bleeding and achieving complete variceal eradication
Defining the advantages and exposing the limitations of endoscopic variceal ligation in controlling acute bleeding and achieving complete variceal eradication Open
EVL was highly effective in controlling the sentinel variceal bleed with an overall 5-day failure to control bleeding of 7.1%. Although repeated EVL achieved complete variceal eradication in less than half of patients with BEV, of whom 62%…