J. E. Till
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View article: A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells<sup>1</sup>
A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells<sup>1</sup> Open
Counts of macroscopic splenic colonies were used to obtain an estimate of the radiation sensitivity of normal mouse bone marrow progenitor cells. Reproduced from Radiation Research 1961(Feb); 14(2): 213-222 by copyright permission of the R…
View article: A Canadian Perspective
A Canadian Perspective Open
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
View article: Finding Canadian cancer clinical trials on the Internet: an exploratory evaluation of online resources.
Finding Canadian cancer clinical trials on the Internet: an exploratory evaluation of online resources. Open
If the PDQ database included all of the NCIC CTG trials, it would become the most complete database of breast cancer clinical trials currently available in Canada. Online cancer data sources should strive to make access to clinical trials …
View article: Success Factors for Open Access
Success Factors for Open Access Open
Open access to the peer-reviewed primary research literature would greatly facilitate knowledge transfer between the creators and the users of the results of research and scholarship. Criteria are needed to assess the impact of recent init…
View article: Ethical issues in qualitative research on internet communities
Ethical issues in qualitative research on internet communities Open
This article was first published in the British Medical Journal Volume 323 Issue 7321. BMJ allows authors to use their own articles for their own non commercial purposes. www.bmj.com Reproduced with permission from Dr. James E. Till
View article: The best things in life are free … at least, some of them are
The best things in life are free … at least, some of them are Open
It's good news that CMAJ was in fifth place among the world's general medical journals in 1999 (after the New England Journal of Medicine , JAMA , The Lancet and BMJ ), when ranked according to impact factors provided by the Institute for …
View article: Predecessors of preprint servers
Predecessors of preprint servers Open
Although there was an early experiment in the 1960s with the central distribution of paper preprints in the biomedical sciences, these sciences have not been early adopters of electronic preprint servers. Some barriers to the development o…
View article: Peer Review in a Post-Eprints World: A Proposal
Peer Review in a Post-Eprints World: A Proposal Open
Recently, a number of electronic biomedical preprints servers, which allow the archiving of electronic papers without prior peer review, have been established, most notably the Clinical Medicine & Health Research NetPrints website and the …
View article: Effect of nonmedical factors on family physicians' decisions about referral for consultation.
Effect of nonmedical factors on family physicians' decisions about referral for consultation. Open
Certain nonmedical considerations may substantially affect physicians' referral practices.
View article: Doctor-patient communication: the Toronto consensus statement.
Doctor-patient communication: the Toronto consensus statement. Open
of 25 000 are expected.'New legislation may be needed.This report was compiled on
View article: Comparison of search strategies on CD Plus/MEDLINE.
Comparison of search strategies on CD Plus/MEDLINE. Open
Strategy A would be more valuable to researchers doing extensive reviews, whereas strategy B would be useful for the busy clinician who simply wants a few appropriate references quickly and is willing to sacrifice comprehensive retrieval i…
View article: Are We Getting Informed Consent from Patients with Cancer?
Are We Getting Informed Consent from Patients with Cancer? Open
We developed a consent form for a hypothetical trial and asked patients to underline information that was pertinent to their decision to accept or refuse to participate in the proposed trial. We also investigated whether patients correctly…
View article: Exemplary family physicians and consultants: empirical definition of contemporary medical practice.
Exemplary family physicians and consultants: empirical definition of contemporary medical practice. Open
To identify the characteristics of exemplary family physicians and consultants, we interviewed 25 family physicians and 25 consultants (5 each in the specialties of internal medicine, obstetrics and gynecology, pediatrics, psychiatry and s…
View article: Cancer Patients: Their Desire for Information and Participation in Treatment Decisions
Cancer Patients: Their Desire for Information and Participation in Treatment Decisions Open
The relationship between cancer patients’ desire for information and their preference for participation in decision making has been examined. Approximately 77% of the 52 patients reported that they had participated in decision making to th…
View article: Proposal to Study a Large Liquid Argon-Uranium Absorber Calorimeter
Proposal to Study a Large Liquid Argon-Uranium Absorber Calorimeter Open
This document proposes a comprehensive program to implement and study a large scale liquid argon-uranium absorber calorimeter sytem in a Fermilab beam. This system is modelled after and contains many of the components of the calorimeters b…
View article: Cellular diversity in the blood-forming system.
Cellular diversity in the blood-forming system. Open
Reused with permission from the Sigma-Xi Sci Research Society. Please refer to the journal publication for the original version.
View article: An approach to classifying prognostic factors related to survival experience for non-Hodgkin's lymphoma patients: Based on a series of 982 patients: 1967–1975
An approach to classifying prognostic factors related to survival experience for non-Hodgkin's lymphoma patients: Based on a series of 982 patients: 1967–1975 Open
The survival experience of 982 non-Hodgkin's lymphoma patients registered at Princess Margaret Hospital, Toronto, between 1967 and 1975, was studied. Prognostic groups were obtained by means of a classification procedure based on standard …
View article: Focus-forming ability and surface markers of hamster-human malignant lymphoma hybrids
Focus-forming ability and surface markers of hamster-human malignant lymphoma hybrids Open
We have examined the properties of hybrid cells formed by polyethylene glycol-mediated fusion of the GRC+L-73 line of Chinese hamster ovary (CHO) cells with peripheral blood cells from patients with chronic lymphocytic leukemia (CLL) or wi…
View article: Focus-forming ability and surface markers of hamster-human malignant lymphoma hybrids
Focus-forming ability and surface markers of hamster-human malignant lymphoma hybrids Open
We have examined the properties of hybrid cells formed by polyethylene glycol-mediated fusion of the GRC+L-73 line of Chinese hamster ovary (CHO) cells with peripheral blood cells from patients with chronic lymphocytic leukemia (CLL) or wi…
View article: Proliferative state of blast cell progenitors in acute myeloblastic leukemia (AML)
Proliferative state of blast cell progenitors in acute myeloblastic leukemia (AML) Open
Peripheral blood from patients with acute myeloblastic leukemia (AML) contains cells capable of giving rise to colonies in culture when stimulated by media conditioned by leukocytes (LCM) in the presence of phytohemagglutinin (PHA). Two ty…
View article: Proliferative state of blast cell progenitors in acute myeloblastic leukemia (AML)
Proliferative state of blast cell progenitors in acute myeloblastic leukemia (AML) Open
Peripheral blood from patients with acute myeloblastic leukemia (AML) contains cells capable of giving rise to colonies in culture when stimulated by media conditioned by leukocytes (LCM) in the presence of phytohemagglutinin (PHA). Two ty…
View article: Assessment of /sup 99/Tc releases to the atmosphere: a plea for applied research. [Dose to man through food chain concentration]
Assessment of /sup 99/Tc releases to the atmosphere: a plea for applied research. [Dose to man through food chain concentration] Open
Recent experimental data suggest that the concentration factor for uptake of /sup 99/Tc by vegetation from soils may be two to three orders of magnitude higher than the 0.25 value currently being used in radiological assessments. Following…
View article: Differentiation in human myeloblastic leukemia studied in cell culture.
Differentiation in human myeloblastic leukemia studied in cell culture. Open
Normal adult hemopoiesis orginates in pluripotent stem cells; among the early differentiated descendents of such cells are progenitors committed to the erythropoietic, granulopoietic, or megakaryocytic pathways of myeloid differentiation. …
View article: Interacting cell populations in cultures of leukocytes from normal or leukemic peripheral blood
Interacting cell populations in cultures of leukocytes from normal or leukemic peripheral blood Open
Kinetic studies in cultures containing 2 X 10(5) peripheral leukocytes from patients with acute myelobastic leukemia revealed extensive, radiation-sensitive increases in thymidine incorporation without parallel increases in cell number. Mo…
View article: Interacting cell populations in cultures of leukocytes from normal or leukemic peripheral blood
Interacting cell populations in cultures of leukocytes from normal or leukemic peripheral blood Open
Kinetic studies in cultures containing 2 X 10(5) peripheral leukocytes from patients with acute myelobastic leukemia revealed extensive, radiation-sensitive increases in thymidine incorporation without parallel increases in cell number. Mo…
View article: Antibodies in human sera to oncorna virus-like proteins from normal or leukemia marrow cell cultures.
Antibodies in human sera to oncorna virus-like proteins from normal or leukemia marrow cell cultures. Open
Some human marrows in culture release particles with oncornavirus-like properties. This study was designed to examine the immunological properties of similar particles in human marrow culture supernates. Leukemic and nonleukemic marrows we…