Garry J.P. Fleming
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View article: Favorable residual stress induction by resin-cementation on dental porcelain
Favorable residual stress induction by resin-cementation on dental porcelain Open
A link between shrinkage stresses associated with the photo-polymerization of dental resin-based cements and the reinforcement of dental porcelain has clearly been established.
View article: The Histone‐Deacetylase‐Inhibitor Suberoylanilide Hydroxamic Acid Promotes Dental Pulp Repair Mechanisms Through Modulation of Matrix Metalloproteinase‐13 Activity
The Histone‐Deacetylase‐Inhibitor Suberoylanilide Hydroxamic Acid Promotes Dental Pulp Repair Mechanisms Through Modulation of Matrix Metalloproteinase‐13 Activity Open
Direct application of histone‐deacetylase‐inhibitors (HDACis) to dental pulp cells (DPCs) induces chromatin changes, promoting gene expression and cellular‐reparative events. We have previously demonstrated that HDACis (valproic acid, tric…
View article: Transcriptional profiling of suberoylanilide hydroxamic acid (SAHA) regulated genes in mineralizing dental pulp cells at early and late time points
Transcriptional profiling of suberoylanilide hydroxamic acid (SAHA) regulated genes in mineralizing dental pulp cells at early and late time points Open
Dental pulp tissue can be damaged by a range of irritants, however, if the irritation is removed and/or the tooth is adequately restored, pulp regeneration is possible (Mjör and Tronstad, 1974 [1]). At present, dental restorative materials…
View article: Epigenetic modulation of dental pulp stem cells: implications for regenerative endodontics
Epigenetic modulation of dental pulp stem cells: implications for regenerative endodontics Open
Dental pulp stem cells ( DPSC s) offer significant potential for use in regenerative endodontics, and therefore, identifying cellular regulators that control stem cell fate is critical to devising novel treatment strategies. Stem cell line…