J. Gordon McComb
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View article: Brain and intracranial volumes are both enlarged and serve as potential risk factors in normal pressure hydrocephalus
Brain and intracranial volumes are both enlarged and serve as potential risk factors in normal pressure hydrocephalus Open
Normal pressure hydrocephalus (NPH) is a poorly understood neurodegenerative condition leading to gait impairment and ultimately dementia. Prior work has shown larger intracranial volume (ICV) among those with NPH which has been taken to e…
View article: Automated Detection of Normal Pressure Hydrocephalus Using CT Imaging for Calculating the Ventricle-to-Subarachnoid Volume Ratio
Automated Detection of Normal Pressure Hydrocephalus Using CT Imaging for Calculating the Ventricle-to-Subarachnoid Volume Ratio Open
Automated assessment of the VSR on head CT images identified probable NPH with 93% accuracy. The assessment of a large cohort of patients with NPH supports the generalizability of clinical screening of CT images. Moreover, the results supp…
View article: Unilateral hemicraniectomy with titanium cranioplasty for the treatment of high intracranial pressure in a pediatric patient with Camurati-Engelmann disease: illustrative case
Unilateral hemicraniectomy with titanium cranioplasty for the treatment of high intracranial pressure in a pediatric patient with Camurati-Engelmann disease: illustrative case Open
BACKGROUND Camurati-Engelmann disease (CED) is an extremely rare autosomal dominant genetic disorder that can cause increased intracranial pressure (ICP) secondary to cranial hyperostosis, which decreases intracranial volume. Surgical proc…
View article: The role of occipital condyle and atlas anomalies on occipital cervical fusion outcomes in Chiari malformation type I with syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium
The role of occipital condyle and atlas anomalies on occipital cervical fusion outcomes in Chiari malformation type I with syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium Open
OBJECTIVE Congenital anomalies of the atlanto-occipital articulation may be present in patients with Chiari malformation type I (CM-I). However, it is unclear how these anomalies affect the biomechanical stability of the craniovertebral ju…
View article: Surgical management of pediatric spinal aneurysmal bone cysts: patient series
Surgical management of pediatric spinal aneurysmal bone cysts: patient series Open
BACKGROUND Aneurysmal bone cysts (ABCs) are rare, highly vascular osteolytic bone lesions that predominantly affect pediatric populations. This report evaluates the clinicopathological data of pediatric patients with spinal ABCs. The medic…
View article: Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus
Quantitative noninvasive measurement of cerebrospinal fluid flow in shunted hydrocephalus Open
OBJECTIVE Standard MRI protocols lack a quantitative sequence that can be used to evaluate shunt-treated patients with a history of hydrocephalus. The objective of this study was to investigate the use of phase-contrast MRI (PC-MRI), a qua…
View article: RETRACTED: When is the radiology report of a posterior fossa containing cyst/cystic-like CSF collection of clinical or surgical significance?
RETRACTED: When is the radiology report of a posterior fossa containing cyst/cystic-like CSF collection of clinical or surgical significance? Open
The authors have requested that this preprint be removed from Research Square.
View article: Eliminating the need for manual segmentation to determine size and volume from MRI. A proof of concept on segmenting the lateral ventricles
Eliminating the need for manual segmentation to determine size and volume from MRI. A proof of concept on segmenting the lateral ventricles Open
Manual segmentation, which is tedious, time-consuming, and operator-dependent, is currently used as the gold standard to validate automatic and semiautomatic methods that quantify geometries from 2D and 3D MR images. This study examines th…
View article: Treatment of hydrocephalus following posterior fossa tumor resection: a multicenter collaboration from the Hydrocephalus Clinical Research Network
Treatment of hydrocephalus following posterior fossa tumor resection: a multicenter collaboration from the Hydrocephalus Clinical Research Network Open
View article: Water displacement device, engines characterization
Water displacement device, engines characterization Open
This dataset contains 44 formulations (rows), 23 features and 1 supervisor factors (24 columns). This data have been extracted from a water displacement device that measures the volume of submerged samples. The displaced water passes throu…
View article: Water displacement device, engines characterization
Water displacement device, engines characterization Open
This dataset contains 44 formulations (rows), 23 features and 1 supervisor factors (24 columns). This data have been extracted from a water displacement device that measures the volume of submerged samples. The displaced water passes throu…
View article: Accurate image-based CSF volume calculation of the lateral ventricles
Accurate image-based CSF volume calculation of the lateral ventricles Open
The size/volume of the brain’s ventricles is essential in diagnosing and treating many neurological disorders, with various forms of hydrocephalus being some of the most common. Initial ventricular size and changes, if any, in response to …
View article: Complications and outcomes of posterior fossa decompression with duraplasty versus without duraplasty for pediatric patients with Chiari malformation type I and syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium
Complications and outcomes of posterior fossa decompression with duraplasty versus without duraplasty for pediatric patients with Chiari malformation type I and syringomyelia: a study from the Park-Reeves Syringomyelia Research Consortium Open
OBJECTIVE The aim of this study was to determine differences in complications and outcomes between posterior fossa decompression with duraplasty (PFDD) and without duraplasty (PFD) for the treatment of pediatric Chiari malformation type I …
View article: An unusual cause of diaphragm pacer failure in congenital central hypoventilation syndrome
An unusual cause of diaphragm pacer failure in congenital central hypoventilation syndrome Open
View article: The First Examination of Diagnostic Performance of Automated Measurement of the Callosal Angle in 1856 Elderly Patients and Volunteers Indicates That 12.4% of Exams Met the Criteria for Possible Normal Pressure Hydrocephalus
The First Examination of Diagnostic Performance of Automated Measurement of the Callosal Angle in 1856 Elderly Patients and Volunteers Indicates That 12.4% of Exams Met the Criteria for Possible Normal Pressure Hydrocephalus Open
In even the most pristine research databases, analyses of the callosal angle indicate that some patients may have normal pressure hydrocephalus. The automatic callosal angle measurement can rapidly and objectively screen for normal pressur…
View article: Ventriculopleural shunts in a pediatric population: a review of 170 consecutive patients
Ventriculopleural shunts in a pediatric population: a review of 170 consecutive patients Open
OBJECTIVE The authors sought to determine the outcome of using the pleural space as the terminus for ventricular CSF-diverting shunts in a pediatric population. METHODS All ventriculopleural (VPl) shunt insertions or revisions done between…
View article: Readmissions after ventricular shunting in pediatric patients with hydrocephalus: a Nationwide Readmissions Database analysis
Readmissions after ventricular shunting in pediatric patients with hydrocephalus: a Nationwide Readmissions Database analysis Open
OBJECTIVE Cerebrospinal fluid diversion via ventricular shunting is a common surgical treatment for hydrocephalus in the pediatric population. No longitudinal follow-up data for a multistate population-based cohort of pediatric patients un…
View article: Measuring Maximum Head Circumference Within the Picture Archiving and Communication System: A Fully Automatic Approach
Measuring Maximum Head Circumference Within the Picture Archiving and Communication System: A Fully Automatic Approach Open
This study describes an automatic technique to accurately determine the maximum head circumference (MHC) measurement from MRI studies within the Picture Archiving and Communications System, and can automatically add this measurement to the…
View article: Extradural decompression versus duraplasty in Chiari malformation type I with syrinx: outcomes on scoliosis from the Park-Reeves Syringomyelia Research Consortium
Extradural decompression versus duraplasty in Chiari malformation type I with syrinx: outcomes on scoliosis from the Park-Reeves Syringomyelia Research Consortium Open
OBJECTIVE Scoliosis is common in patients with Chiari malformation type I (CM-I)–associated syringomyelia. While it is known that treatment with posterior fossa decompression (PFD) may reduce the progression of scoliosis, it is unknown if …
View article: Occipital-Cervical Fusion and Ventral Decompression in the Surgical Management of Chiari-1 Malformation and Syringomyelia: Analysis of Data From the Park-Reeves Syringomyelia Research Consortium
Occipital-Cervical Fusion and Ventral Decompression in the Surgical Management of Chiari-1 Malformation and Syringomyelia: Analysis of Data From the Park-Reeves Syringomyelia Research Consortium Open
BACKGROUND Occipital-cervical fusion (OCF) and ventral decompression (VD) may be used in the treatment of pediatric Chiari-1 malformation (CM-1) with syringomyelia (SM) as adjuncts to posterior fossa decompression (PFD) for complex craniov…
View article: Resolution of neonatal posthemorrhagic ventricular dilation coincident with patent ductus arteriosus ligation: case report
Resolution of neonatal posthemorrhagic ventricular dilation coincident with patent ductus arteriosus ligation: case report Open
Preterm infants commonly present with a hemodynamically significant patent ductus arteriosus (hsPDA). The authors describe the case of a preterm infant with posthemorrhagic ventricular dilation, which resolved in a temporally coincident fa…
View article: Automatically measuring brain ventricular volume within PACS using artificial intelligence
Automatically measuring brain ventricular volume within PACS using artificial intelligence Open
The picture archiving and communications system (PACS) is currently the standard platform to manage medical images but lacks analytical capabilities. Staying within PACS, the authors have developed an automatic method to retrieve the medic…
View article: The effect of NACHRI children’s hospital designation on outcome in pediatric malignant brain tumors
The effect of NACHRI children’s hospital designation on outcome in pediatric malignant brain tumors Open
OBJECTIVE Although current pediatric neurosurgery guidelines encourage the treatment of pediatric malignant brain tumors at specialized centers such as pediatric hospitals, there are limited data in support of this recommendation. Previous…
View article: Extending PACS functionality: towards facilitating the conversion of clinical necessities into research-derived applications
Extending PACS functionality: towards facilitating the conversion of clinical necessities into research-derived applications Open
The Picture Administration and Communications System (PACS) was designed to replace the old film archiving system in hospitals in order to store and move varying medical image modalities. Using the standard Internet transport protocol, PAC…
View article: GC-07INVESTIGATING A THICKENED PITUITARY STALK IN CHILDREN: VALIDATING A PROSPECTIVE DIAGNOSIS AND TREATMENT PARADIGM
GC-07INVESTIGATING A THICKENED PITUITARY STALK IN CHILDREN: VALIDATING A PROSPECTIVE DIAGNOSIS AND TREATMENT PARADIGM Open
View article: Surgical management of hydrocephalus secondary to intraventricular hemorrhage in the preterm infant
Surgical management of hydrocephalus secondary to intraventricular hemorrhage in the preterm infant Open
OBJECT Posthemorrhagic hydrocephalus (PHH) in the preterm infant remains a major neurological complication of prematurity. The authors first described insertion of a specially designed low-profile subcutaneous ventricular catheter reservoi…
View article: Trends in hospitalization of preterm infants with intraventricular hemorrhage and hydrocephalus in the United States, 2000–2010
Trends in hospitalization of preterm infants with intraventricular hemorrhage and hydrocephalus in the United States, 2000–2010 Open
OBJECT Even with improved prenatal and neonatal care, intraventricular hemorrhage (IVH) occurs in approximately 25%–30% of preterm infants, with a subset of these patients developing hydrocephalus. This study was undertaken to describe cur…
View article: Reevaluating the weekend effect on patients with hydrocephalus undergoing operative shunt intervention
Reevaluating the weekend effect on patients with hydrocephalus undergoing operative shunt intervention Open
OBJECT Recently published data have suggested an increase in adverse outcomes in pediatric patients after insertion or revision of a ventricular CSF diversion shunt after a same-day weekend procedure. The authors undertook an evaluation of…
View article: Intracranial hypertension after surgical correction for craniosynostosis: a systematic review
Intracranial hypertension after surgical correction for craniosynostosis: a systematic review Open
OBJECT The authors’ aim was perform a systematic review on the incidence of intracranial hypertension (IH) after surgery for craniosynostosis. METHODS A systematic literature review was conducted using PubMed to assess the rate of postoper…
View article: Risk factors for hydrocephalus and neurological deficit in children born with an encephalocele
Risk factors for hydrocephalus and neurological deficit in children born with an encephalocele Open
OBJECT There is a known association of hydrocephalus with encephaloceles. Risk factors for hydrocephalus and neurological deficit were ascertained in a series of patients born with an encephalocele. METHODS A retrospective analysis was und…