John Hodgson
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View article: A National Vegetation Plot Database for Great Britain
A National Vegetation Plot Database for Great Britain Open
The GBNVPD (GIVD-code EU-GB-007) is the new centralised repository for the collection and storage of standardised vegetation plot data in Great Britain and the Crown Dependencies. The initial version of the GBNVPD (v1.0) described in this …
View article: Activity of Brigatinib in Patients With Crizotinib-Resistant ALK-positive Non–Small-Cell Lung Cancer According to ALK Fusion and Mutation Status
Activity of Brigatinib in Patients With Crizotinib-Resistant ALK-positive Non–Small-Cell Lung Cancer According to ALK Fusion and Mutation Status Open
Brigatinib showed substantial activity in crizotinib-pretreated ALK-positive NSCLC with ALK-dependent mechanisms of resistance. Patients with non-ALK canonical drivers did not respond to brigatinib, suggesting alternative therapeutic appro…
View article: Targeted transcriptional downregulation of MYC using epigenomic controllers demonstrates antitumor activity in hepatocellular carcinoma models
Targeted transcriptional downregulation of MYC using epigenomic controllers demonstrates antitumor activity in hepatocellular carcinoma models Open
View article: PJY04 Head-to-head comparison of the Cambridge Prognostic and European Association of Urology risk groups: Results from a large multi-centre database
PJY04 Head-to-head comparison of the Cambridge Prognostic and European Association of Urology risk groups: Results from a large multi-centre database Open
View article: Correction: Seeing the fields through the weeds: introducing the WeedEco R package for comparing past and present arable farming systems using functional weed ecology
Correction: Seeing the fields through the weeds: introducing the WeedEco R package for comparing past and present arable farming systems using functional weed ecology Open
View article: Seeing the fields through the weeds: introducing the WeedEco R package for comparing past and present arable farming systems using functional weed ecology
Seeing the fields through the weeds: introducing the WeedEco R package for comparing past and present arable farming systems using functional weed ecology Open
View article: Drug pipeline 1Q23 — Everything everywhere all over the place
Drug pipeline 1Q23 — Everything everywhere all over the place Open
View article: Feeding Anglo-Saxon England: a bioarchaeological dataset for the study of early medieval agriculture (Data paper)
Feeding Anglo-Saxon England: a bioarchaeological dataset for the study of early medieval agriculture (Data paper) Open
The FeedSax project combined bioarchaeological data with evidence from settlement archaeology to investigate how, when and why the expansion of arable farming occurred between the 8th-13th centuries in England. It has generated and release…
View article: Supplementary Table 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Table 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 52K
View article: Supplementary Figure 2 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 2 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 86K
View article: Supplementary Table 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Table 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 52K
View article: Supplementary Table 4 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Table 4 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 49K
View article: Supplementary Figure 7 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 7 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 78K
View article: Data from Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers
Data from Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers Open
Purpose:The purpose of this study is to evaluate ponatinib for advanced gastrointestinal stromal tumors (GIST).Patients and Methods:This single-arm phase II trial enrolled patients with metastatic and/or unresectable GIST with failure of p…
View article: Supplementary Figure 6 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 6 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 185K
View article: Supplementary Figure 7 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 7 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 78K
View article: Supplementary Figure 1 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 1 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 115K
View article: Data from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Data from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
Purpose: Malignant astrocytomas (MA) are aggressive central nervous system tumors with poor prognosis. Activating mutation of BRAF (BRAFV600E) has been reported in a subset of these tumors, especially in chi…
View article: Supplementary Figure 9 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 9 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 374K
View article: Supplementary Figure 8 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 8 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 222K
View article: Supplementary Figure 5 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 5 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 154K
View article: Data from Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers
Data from Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers Open
Purpose:The purpose of this study is to evaluate ponatinib for advanced gastrointestinal stromal tumors (GIST).Patients and Methods:This single-arm phase II trial enrolled patients with metastatic and/or unresectable GIST with failure of p…
View article: Supplementary Figure 5 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 5 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 154K
View article: Supplementary Figure 9 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 9 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 374K
View article: Supplementary Figure 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 3 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 261K
View article: Supplementary Figure 2 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 2 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 86K
View article: Supplementary Figure 4 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Figure 4 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 48K
View article: Data from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Data from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
Purpose: Malignant astrocytomas (MA) are aggressive central nervous system tumors with poor prognosis. Activating mutation of BRAF (BRAFV600E) has been reported in a subset of these tumors, especially in chi…
View article: Supplementary Data from Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers
Supplementary Data from Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers Open
Supplementary Data from Phase II Study of Ponatinib in Advanced Gastrointestinal Stromal Tumors: Efficacy, Safety, and Impact of Liquid Biopsy and Other Biomarkers
View article: Supplementary Table 2 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma
Supplementary Table 2 from Targeted Therapy for <i>BRAF<sup>V600E</sup></i> Malignant Astrocytoma Open
PDF file - 42K