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View article: Postauthorization safety study (NISSO) assessing the long-term safety profile of sonidegib in patients with locally advanced basal cell carcinoma: interim analysis from the Spanish cohort
Postauthorization safety study (NISSO) assessing the long-term safety profile of sonidegib in patients with locally advanced basal cell carcinoma: interim analysis from the Spanish cohort Open
View article: Automated triage of cancer-suspicious skin lesions with 3D total-body photography
Automated triage of cancer-suspicious skin lesions with 3D total-body photography Open
View article: Special Issue on Artificial Intelligence in Dermatology: A Call for Collaborative Innovation
Special Issue on Artificial Intelligence in Dermatology: A Call for Collaborative Innovation Open
View article: Advancements in Diagnosis of Neoplastic and Inflammatory Skin Diseases: Old and Emerging Approaches
Advancements in Diagnosis of Neoplastic and Inflammatory Skin Diseases: Old and Emerging Approaches Open
Background: In recent decades, dermatological diagnostics have undergone a profound transformation, driven by the integration of new technologies alongside traditional methods. Classic techniques such as the Tzanck smear, potassium hydroxi…
View article: Skin region images extracted from 3D total body photographs for lesion detection
Skin region images extracted from 3D total body photographs for lesion detection Open
Artificial intelligence has significantly advanced skin cancer diagnosis by enabling rapid and accurate detection of malignant lesions. In this domain, most publicly available image datasets consist of single, isolated skin lesions positio…
View article: Correlation of Vascular Patterns in Skin Lesions With LC-OCT and Dermoscopy With a Tridimensional Perspective: A Pilot Study
Correlation of Vascular Patterns in Skin Lesions With LC-OCT and Dermoscopy With a Tridimensional Perspective: A Pilot Study Open
Introduction: Vascular patterns play a crucial role in the diagnosis and differentiation of skin lesions by providing insight into underlying pathology and aid in distinguishing between benign and malignant lesions. While dermoscopy has pr…
View article: Integrative Molecular and Immune Profiling in Advanced Unresectable Melanoma: Tumor Microenvironment and Peripheral PD-1+ CD4+ Effector Memory T-Cells as Potential Markers of Response to Immune Checkpoint Inhibitor Therapy
Integrative Molecular and Immune Profiling in Advanced Unresectable Melanoma: Tumor Microenvironment and Peripheral PD-1+ CD4+ Effector Memory T-Cells as Potential Markers of Response to Immune Checkpoint Inhibitor Therapy Open
Background/Objectives: Immune checkpoint inhibitors (ICIs) have revolutionized advanced melanoma treatment, yet many patients fail to achieve sustained clinical benefit. Several biomarkers, including tumor microenvironment (TME) signature,…
View article: Inflammatory Cell Immunophenotypes in Regressing Melanomas and Halo Nevi: Possible Keys to Distinguish Intensely Inflamed Tumors
Inflammatory Cell Immunophenotypes in Regressing Melanomas and Halo Nevi: Possible Keys to Distinguish Intensely Inflamed Tumors Open
Results indicate a stronger cytotoxic reaction and consequently a regulatory mechanism in halo nevi, characterized by increased PD1, FOXP3, and CD25. This research further characterizes halo nevi and regressing melanomas, and shows possibl…
View article: Morphological Evaluation of Facial Pigmented Lesions With Line-Field Confocal Optical Coherence Tomography: Correlation With Reflectance Confocal Microscopy. A Pilot Study
Morphological Evaluation of Facial Pigmented Lesions With Line-Field Confocal Optical Coherence Tomography: Correlation With Reflectance Confocal Microscopy. A Pilot Study Open
Introduction: Facial pigmented lesions pose significant challenges for diagnosis and treatment planning due to their anatomical topography and complexity. Traditional methods like dermoscopy have limitations, and while reflectance confocal…
View article: Management of Local Skin Reactions Caused by 5-FU 4% Cream for the Treatment of Actinic Keratosis: A Delphi Consensus
Management of Local Skin Reactions Caused by 5-FU 4% Cream for the Treatment of Actinic Keratosis: A Delphi Consensus Open
Introduction: Treatments such as 4% 5-fluorouracil (5-FU) cream have demonstrated strong efficacy in lesion clearance of actinic keratosis; however, local skin reactions (LSR) during treatment remain a significant challenge, potentially af…
View article: [Artículo traducido] Melanoma acral en población caucásica: estudio de cohorte sobre factores epidemiológicos, clinicopatológicos y pronósticos
[Artículo traducido] Melanoma acral en población caucásica: estudio de cohorte sobre factores epidemiológicos, clinicopatológicos y pronósticos Open
This study, the largest in a predominantly Caucasian population, underscores the unfavorable outcomes of acral melanoma. Foot melanomas exhibited delayed detection, increased invasiveness, thicker Breslow depth, increased sentinel lymph no…
View article: Advanced Doppler Ultrasound Insights: A Multicenter Prospective Study on Healthy Skin
Advanced Doppler Ultrasound Insights: A Multicenter Prospective Study on Healthy Skin Open
Background: There have been multiple studies on the use of Doppler ultrasound to define skin inflammation, but the visible vessels of healthy skin have yet to be described. Objective: This study aimed to evaluate the visible vessels of hea…
View article: The iToBoS dataset: skin region images extracted from 3D total body photographs for lesion detection
The iToBoS dataset: skin region images extracted from 3D total body photographs for lesion detection Open
Artificial intelligence has significantly advanced skin cancer diagnosis by enabling rapid and accurate detection of malignant lesions. In this domain, most publicly available image datasets consist of single, isolated skin lesions positio…
View article: Clinical Outcomes of 3d-Total Body Photography and Digital Dermoscopy for Surveillance of High-Risk Melanoma Patients. A Prospective Longitudinal Observational Study
Clinical Outcomes of 3d-Total Body Photography and Digital Dermoscopy for Surveillance of High-Risk Melanoma Patients. A Prospective Longitudinal Observational Study Open
View article: Characterization of Resection Margins for Basal Cell Carcinomas (BCC) Using LC-OCT Co-localized with Dermoscopy and AI Assistance
Characterization of Resection Margins for Basal Cell Carcinomas (BCC) Using LC-OCT Co-localized with Dermoscopy and AI Assistance Open
View article: First Description of Triple Co-Localization Using x400 Super-Magnified Dermoscopy, LC-OCT, and x20 Dermoscopy
First Description of Triple Co-Localization Using x400 Super-Magnified Dermoscopy, LC-OCT, and x20 Dermoscopy Open
View article: Modelling the impact of microbiome on immunotherapy efficacy in metastatic melanoma patients
Modelling the impact of microbiome on immunotherapy efficacy in metastatic melanoma patients Open
View article: Performance of Artificial Intelligence algorithms/applications for lesion change detection in 2D and 3D automated Total Body Photography in patients at high risk for developing melanoma
Performance of Artificial Intelligence algorithms/applications for lesion change detection in 2D and 3D automated Total Body Photography in patients at high risk for developing melanoma Open
View article: Characterization of global cfDNA fragmentomics in Melanoma Patients
Characterization of global cfDNA fragmentomics in Melanoma Patients Open
View article: Applicability of 3D Total Body Photography and machine learning tools to estimate body surface involvement and neurocutaneous melanosis risk in giant and large congenital melanocytic nevi patients
Applicability of 3D Total Body Photography and machine learning tools to estimate body surface involvement and neurocutaneous melanosis risk in giant and large congenital melanocytic nevi patients Open
View article: Application of Raman Confocal Microspectroscopy Guided by LC-OCT for AI-Supervised Chemical Characterization of Basal Cell Carcinoma
Application of Raman Confocal Microspectroscopy Guided by LC-OCT for AI-Supervised Chemical Characterization of Basal Cell Carcinoma Open
View article: A computational tool for exploiting variant calling data in melanoma progression studies
A computational tool for exploiting variant calling data in melanoma progression studies Open
View article: Melanocytic Clefting Observed Using LC-OCT
Melanocytic Clefting Observed Using LC-OCT Open
View article: Molecular and Immune Biomarkers of Immunotherapy Response in Advanced Melanoma: Insights from RNA Profiling and Mass Cytometry
Molecular and Immune Biomarkers of Immunotherapy Response in Advanced Melanoma: Insights from RNA Profiling and Mass Cytometry Open
View article: Deep Phenotyping with 3D Total Body Photography and Artificial Intelligence for Patients at High Risk of Developing Melanoma
Deep Phenotyping with 3D Total Body Photography and Artificial Intelligence for Patients at High Risk of Developing Melanoma Open
View article: Desmoplastic Melanoma: Clinical Features, Prognostic Implications, and Survival Analysis from a 24-Year Cohort Study
Desmoplastic Melanoma: Clinical Features, Prognostic Implications, and Survival Analysis from a 24-Year Cohort Study Open
View article: Predictive Models of Melanoma Metastasis Based on Dermatoscopy: An International Human Reader Study
Predictive Models of Melanoma Metastasis Based on Dermatoscopy: An International Human Reader Study Open
View article: Distinct Transcriptomic and Tumor Microenvironment Profiles in Sinonasal Mucosal Melanoma and Aggressive Cutaneous Melanomas
Distinct Transcriptomic and Tumor Microenvironment Profiles in Sinonasal Mucosal Melanoma and Aggressive Cutaneous Melanomas Open
Background/Objectives: Sinonasal mucosal melanoma (SNMM) is a rare and aggressive melanoma subtype with a notably poor prognosis compared to cutaneous melanoma (CM). Despite advances in molecular characterization, SNMM remains underexplore…
View article: Effect of patient‐contextual skin images in human‐ and artificial intelligence‐based diagnosis of melanoma: Results from the 2020 <scp>SIIM</scp>‐<scp>ISIC</scp> melanoma classification challenge
Effect of patient‐contextual skin images in human‐ and artificial intelligence‐based diagnosis of melanoma: Results from the 2020 <span>SIIM</span>‐<span>ISIC</span> melanoma classification challenge Open
Background While the high accuracy of reported AI tools for melanoma detection is promising, the lack of holistic consideration of the patient is often criticized. Along with medical history, a dermatologist would also consider intra‐patie…
View article: European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics - Update 2024
European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics - Update 2024 Open