Warren J. Manning
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View article: Standing transthoracic echocardiography: a feasibility study
Standing transthoracic echocardiography: a feasibility study Open
Background Orthostatic hypotension (OH) is associated with cardiovascular disease, particularly among older adults. While a standing transthoracic echocardiogram (TTE) could theoretically identify changes in cardiac output to diagnose card…
View article: Radiomic Cardiac MRI Signatures for Predicting Ventricular Arrhythmias in Patients With Nonischemic Dilated Cardiomyopathy
Radiomic Cardiac MRI Signatures for Predicting Ventricular Arrhythmias in Patients With Nonischemic Dilated Cardiomyopathy Open
In this proof-of-concept study, radiomic analysis of LGE images provides additional prognostic value beyond LGE presence in predicting arrhythmia in patients with DCM.
View article: Cardiovascular magnetic resonance radiologic-pathologic correlation in radiomic analysis of myocardium in non-ischemic dilated cardiomyopathy
Cardiovascular magnetic resonance radiologic-pathologic correlation in radiomic analysis of myocardium in non-ischemic dilated cardiomyopathy Open
In DCM patients, CMR radiomic signatures were associated with myocardial tissue composition, as assessed by invasive biopsy.
View article: CMR phenotyping of asymptomatic hypertrophic cardiomyopathy at increased risk for heart failure progression
CMR phenotyping of asymptomatic hypertrophic cardiomyopathy at increased risk for heart failure progression Open
View article: Free-breathing single-beat exercise cardiovascular magnetic resonance with generative artificial intelligence for evaluation of volumetric and functional cardiac indices: A reproducibility study
Free-breathing single-beat exercise cardiovascular magnetic resonance with generative artificial intelligence for evaluation of volumetric and functional cardiac indices: A reproducibility study Open
Single-beat Ex-CMR enabled evaluation of biventricular volumetric and functional indices with excellent reproducibility.
View article: Exercise cardiovascular magnetic resonance myocardial dynamic index: A non-invasive imaging marker associated with cardiac dyspnea
Exercise cardiovascular magnetic resonance myocardial dynamic index: A non-invasive imaging marker associated with cardiac dyspnea Open
Ex-CMR MDI is independently associated with cardiac dyspnea and strongly correlates with the VO₂ max index. It aids in differentiating cardiac from non-cardiac dyspnea and provides incremental diagnostic value beyond conventional clinical …
View article: Normal ratios of right and left-sided parameters in adults free of cardiovascular disease: The Framingham heart study
Normal ratios of right and left-sided parameters in adults free of cardiovascular disease: The Framingham heart study Open
View article: Accelerated phase-contrast magnetic resonance imaging with use of resolution enhancement generative adversarial neural network
Accelerated phase-contrast magnetic resonance imaging with use of resolution enhancement generative adversarial neural network Open
We demonstrated the potential of CRISPFlow to accelerate phase contrast CMR.
View article: Late gadolinium enhancement cardiovascular magnetic resonance with generative artificial intelligence
Late gadolinium enhancement cardiovascular magnetic resonance with generative artificial intelligence Open
The generative AI-based model enhances the image quality of 2D LGE images while reducing the scan time and preserving imaging sharpness. Further evaluation in a large cohort is needed to assess the clinical utility of AI-enhanced LGE image…
View article: Increased Aortic Stiffness With Acute Exercise in Heart Failure: Assessment by Cardiovascular Magnetic Resonance
Increased Aortic Stiffness With Acute Exercise in Heart Failure: Assessment by Cardiovascular Magnetic Resonance Open
View article: Cardiovascular Magnetic Resonance Radiomics to Identify Components of the Extracellular Matrix in Dilated Cardiomyopathy
Cardiovascular Magnetic Resonance Radiomics to Identify Components of the Extracellular Matrix in Dilated Cardiomyopathy Open
BACKGROUND: Current cardiovascular magnetic resonance sequences cannot discriminate between different myocardial extracellular space (ECSs), including collagen, noncollagen, and inflammation. We sought to investigate whether cardiovascular…
View article: ECG and Atrial Appendage Doppler Discordance Is Common in Patients Undergoing Cardiac Surgery
ECG and Atrial Appendage Doppler Discordance Is Common in Patients Undergoing Cardiac Surgery Open
A large minority of patients without a history of AF undergoing cardiac surgery have ECG/atrial appendage Doppler discordance, a setting that may promote thromboembolism in non-anticoagulated patients. Clinical parameters do not identify p…
View article: <scp>MRI</scp> Assessment of Myocardial Deformation for Risk Stratification of Major Arrhythmic Events in Patients With Non‐Ischemic Cardiomyopathy Eligible for Primary Prevention Implantable Cardioverter Defibrillators
<span>MRI</span> Assessment of Myocardial Deformation for Risk Stratification of Major Arrhythmic Events in Patients With Non‐Ischemic Cardiomyopathy Eligible for Primary Prevention Implantable Cardioverter Defibrillators Open
Background Implantable cardioverter‐defibrillator (ICD) intervention is an established prophylactic measure. Identifying high‐benefit patients poses challenges. Purpose To assess the prognostic value of cardiac magnetic resonance imaging (…
View article: Present and Future Innovations in AI and Cardiac MRI
Present and Future Innovations in AI and Cardiac MRI Open
Cardiac MRI is used to diagnose and treat patients with a multitude of cardiovascular diseases. Despite the growth of clinical cardiac MRI, complicated image prescriptions and long acquisition protocols limit the specialty and restrain its…
View article: Discordance Between Myocardial Contraction FBaction by Volumetric versus Geometric Formula-based Methods
Discordance Between Myocardial Contraction FBaction by Volumetric versus Geometric Formula-based Methods Open
View article: Sex-differences in Relationships Between Ventricular Strain and Age in the Community
Sex-differences in Relationships Between Ventricular Strain and Age in the Community Open
View article: Increased Aortic Stiffness with Acute Exercise in Heart Failure Assessment by Cardiovascular Magnetic Resonance
Increased Aortic Stiffness with Acute Exercise in Heart Failure Assessment by Cardiovascular Magnetic Resonance Open
View article: Accelerated myocardial fibrosis in young to middle-aged patients with hypertrophic cardiomyopathy
Accelerated myocardial fibrosis in young to middle-aged patients with hypertrophic cardiomyopathy Open
In HCM, progressive fibrosis occurs more frequently in young to middle-aged patients, underscoring the importance of repeating CMR to re-evaluate for potential LGE progression in this age group.
View article: Obesity-Related Differences in Pathomechanism and Outcomes in Patients With HFpEF
Obesity-Related Differences in Pathomechanism and Outcomes in Patients With HFpEF Open
View article: Echocardiographic Progression of Peak Tricuspid Regurgitant Velocity Among Medicare Beneficiaries
Echocardiographic Progression of Peak Tricuspid Regurgitant Velocity Among Medicare Beneficiaries Open
In this large, multidecade study of Medicare beneficiaries with serial TTEs performed in the outpatient setting, the mean rate of TRV progression was 0.23 m/s/y. Older age, left heart disease, and adverse metabolic features were associated…
View article: Accelerated Cardiac MRI Cine with Use of Resolution Enhancement Generative Adversarial Inline Neural Network
Accelerated Cardiac MRI Cine with Use of Resolution Enhancement Generative Adversarial Inline Neural Network Open
Background Cardiac cine can benefit from deep learning-based image reconstruction to reduce scan time and/or increase spatial and temporal resolution. Purpose To develop and evaluate a deep learning model that can be combined with parallel…
View article: Highly accelerated free-breathing real-time myocardial tagging for exercise cardiovascular magnetic resonance
Highly accelerated free-breathing real-time myocardial tagging for exercise cardiovascular magnetic resonance Open
View article: The spatial ventricular gradient is associated with adverse outcomes in acute pulmonary embolism
The spatial ventricular gradient is associated with adverse outcomes in acute pulmonary embolism Open
Background The spatial ventricular gradient (SVG) is a vectorcardiographic measurement that reflects cardiac loading conditions via electromechanical coupling. Objectives We hypothesized that the SVG is correlated with right ventricular (R…
View article: Cross‐Sectional Relationships of Proximal Aortic Stiffness and Left Ventricular Diastolic Function in Adults in the Community
Cross‐Sectional Relationships of Proximal Aortic Stiffness and Left Ventricular Diastolic Function in Adults in the Community Open
Background Stiffness of the proximal aorta may play a critical role in adverse left ventricular (LV)–vascular interactions and associated LV diastolic dysfunction. In a community‐based sample, we sought to determine the association between…
View article: Impact of the COVID-19 pandemic on cardiology fellow echocardiography education at a large academic center
Impact of the COVID-19 pandemic on cardiology fellow echocardiography education at a large academic center Open
View article: Relation of MRI Aortic Wall Area and Plaque to Incident Cardiovascular Events: The Framingham Heart Study
Relation of MRI Aortic Wall Area and Plaque to Incident Cardiovascular Events: The Framingham Heart Study Open
Background Arterial arteriosclerosis and atherosclerosis reflect vascular disease, the subclinical detection of which allows opportunity for cardiovascular disease (CVD) prevention. Larger cohort studies simultaneously quantifying anatomic…
View article: 2021–2022 state of our JCMR
2021–2022 state of our JCMR Open
View article: 2021 -Â State of our JCMR
2021 -Â State of our JCMR Open
View article: An inline deep learning based free-breathing ECG-free cine for exercise cardiovascular magnetic resonance
An inline deep learning based free-breathing ECG-free cine for exercise cardiovascular magnetic resonance Open
View article: Development and validation of an echocardiographic algorithm to predict long-term mitral and tricuspid regurgitation progression
Development and validation of an echocardiographic algorithm to predict long-term mitral and tricuspid regurgitation progression Open
Aims Prediction of mitral (MR) and tricuspid (TR) regurgitation progression on transthoracic echocardiography (TTE) is needed to personalize valvular surveillance intervals and prognostication. Methods and results Structured TTE report dat…