John P. Minton
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View article: Insufficient penetration of systemic vancomycin into the PermCath lumen
Insufficient penetration of systemic vancomycin into the PermCath lumen Open
Despite serum vancomycin concentration of approximately 17 microg/ml in each group, the vancomycin concentration in the venous hub of the catheter was only 0.2+/-0.6 microg/ml in the former group, in sharp contrast to 125. 6+/-13 microg/ml…
View article: Age‐related changes in oral sensation
Age‐related changes in oral sensation Open
Oral sensation (including two‐point discrimination, oral stereognosis, vibrotactile detection, somesthetic sensitivity, proprioception, and thermal sensitivity) was studied in 60 healthy adults in five age categories: 20 to 34, 35 to 49, 5…
View article: CEA-Directed Second-look Surgery in the Asymptomatic Patient after Primary Resection of Colorectal Carcinoma
CEA-Directed Second-look Surgery in the Asymptomatic Patient after Primary Resection of Colorectal Carcinoma Open
Since 1971, serial carcinoembryonic antigen (CEA) levels have been measured to monitor patients after primary resection of colorectal cancer. Based solely on a rise in CEA level above the baseline established after primary resection, 146 p…
View article: Results of a 400-patient carcinoembryonic antigen second-look colorectal cancer study
Results of a 400-patient carcinoembryonic antigen second-look colorectal cancer study Open
Four hundred patients with resectable colon and rectal cancers were operated on by 37 surgeons at 31 institutions. Patients were monitored with carcinoembryonic antigen (CEA) level determinations and clinical examinations. One hundred thir…
View article: Caffeine and unsaturated fat diet significantly promotes DMBA-induced breast cancer in rats
Caffeine and unsaturated fat diet significantly promotes DMBA-induced breast cancer in rats Open
The following study was carried out to determine the possibility of caffeine being a promoter of breast cancer development in animals consuming vegetable fat. A controlled study, comparing the time of mammary tumor development and the numb…
View article: The Ohio State University Commencement Address by John P. Minton, Summer 1982
The Ohio State University Commencement Address by John P. Minton, Summer 1982 Open
Commencement address given by Dr. John Peter Minton, Professor of Surgery at The Ohio State University School of Medicine, to the Summer 1982 graduating class of The Ohio State University, St. John Arena, Columbus, Ohio, September 2, 1982.
View article: Brief Note Elemental Analysis of Biological Material in the Fresh-Frozen State
Brief Note Elemental Analysis of Biological Material in the Fresh-Frozen State Open
Author Institution: Department of Zoology and Department of Surgery, The Ohio State University
View article: The use of serial CEA determinations to predict recurrence of colon cancer and when to do a second-look operation
The use of serial CEA determinations to predict recurrence of colon cancer and when to do a second-look operation Open
The concept of second-look surgery was introduced by Wangensteen 25 years ago, and 17% of patients were reported to be converted to a cancer-free state. Instead of an arbitrary time interval for reoperation, serial CEA values were used as …
View article: The USE of CEA as an early indicator for gastrointestinal tumor recurrence and second-look procedures
The USE of CEA as an early indicator for gastrointestinal tumor recurrence and second-look procedures Open
Since 1972 plasma CEA levels of 25 cancer patients have been assayed to evaluate the reliability of CEA as an early indicator of recurrent gastrointestinal cancer. Identification of significant elevations in CEA levels required definition …
View article: A phase III study comparing the clinical utility of four regimens of 5-Fluorouracil.A preliminary report
A phase III study comparing the clinical utility of four regimens of 5-Fluorouracil.A preliminary report Open
A clinical trial involving 462 colon, rectum, and breast cancer patients randomized among four different dosage regimens of 5-FU (an intravenous loading course, a weekly intravenous schedule, a nontoxic schedule, and an oral schedule) has …
View article: Observations on the Postoperative Tumor Growth Behavior of Certain Islet Cell Tumors
Observations on the Postoperative Tumor Growth Behavior of Certain Islet Cell Tumors Open
Over a period of 21 years 39 patients with gastrinoma were surgically treated. Thirty-three patients had total gastrectomy with two postoperative deaths, and 6 patients had a lesser procedure. The postoperative fasting gastrin levels remai…
View article: The effect of Corynebacterium parvum on the humoral and cellular immune systems in patients with breast cancer.
The effect of Corynebacterium parvum on the humoral and cellular immune systems in patients with breast cancer. Open
Corynebacterium parvum, a Gram-positive anaerobic bacillus thought to be a strong immunological stimulant, has been shown to decrease tumour growth and prolong survival in patients with metastatic disease. Study of the effect of a single i…
View article: Cellular imunity in neoplasia: <i>Antigen and mitogen responses in patients with bronchiogenic carcinoma</i>
Cellular imunity in neoplasia: <i>Antigen and mitogen responses in patients with bronchiogenic carcinoma</i> Open
Cellular immune responses of patients with histologically confirmed lung carcinoma were assessed in vivo using cutaneous response and in vitro with a microlymphocyte blastogenic transformation (LBT) assay. In addition, correlation of the c…
View article: Mesenteric Thrombosis Following Splenectomy
Mesenteric Thrombosis Following Splenectomy Open
Three cases of postsplenectomy mesenteric thrombosis, two associated with thrombocytosis, are presented. Experience has shown that persistent thrombocytosis, accompanied by abnormal platelet function, is not a benign condition and may be a…
View article: The response of breast cancer patients with bone pain to L-dopa
The response of breast cancer patients with bone pain to L-dopa Open
Levodopa provides relief from the bone pain caused by metastatic breast cancer in one of three such patients. Pain relief from Levodopa has successfully predicted a favorable clinical response to surgical endocrine alteration by oophorecto…
View article: A correlation of the laser wavelength absorption capabilities of experimental and human tumors.Relationship to the quantitation of human tumor destruction by pulsed laser radiation
A correlation of the laser wavelength absorption capabilities of experimental and human tumors.Relationship to the quantitation of human tumor destruction by pulsed laser radiation Open
The laser wavelength-absorption capabilities of 9 experimental animal tumor homogenates and 16 human tumor homogenates were determined using a technique described in this paper. Eight of the experimental tumors and 9 of the human tumors de…
View article: A comparison of survival time and extent of tumor metastases in mice with transplanted, induced and spontaneous tumors
A comparison of survival time and extent of tumor metastases in mice with transplanted, induced and spontaneous tumors Open
TUMOR GROWTH AFTER RE-V peated transplantation has resulted in reports indicating that transplanted tumor systems are less representative of human tumor systems than either induced or spontaneous tumor systems.6Indeed in many respects thes…
View article: The Dynamical Function of the Tympanic Membrane and Its Associated Ossicles
The Dynamical Function of the Tympanic Membrane and Its Associated Ossicles Open
of this note is to point out that the principle of microscopic reversibility can be regarded at the present time only as an unproved assumption. Although closely connected with the second law of thermodynamics, it cannot be derived therefr…
View article: Correlation between Physical and Medical Findings on Normal Ears
Correlation between Physical and Medical Findings on Normal Ears Open
Humans become increasingly fragile as they age. We show that something similar may happen to states, although for states, the risk of termination levels off as they grow older, allowing some to persist for millennia. Proximate causes of th…
View article: An investigation of dielectic losses with the cathode ray tube
An investigation of dielectic losses with the cathode ray tube Open
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