Jens Bertram
YOU?
Author Swipe
View article: Zinc, Fe2+ and Fe3+ differentially influence IFN-γ production in human peripheral blood mononuclear cells
Zinc, Fe2+ and Fe3+ differentially influence IFN-γ production in human peripheral blood mononuclear cells Open
Iron (II) and zinc both suppress cytokine production in MLC. Fe3+ shows a significantly different effect on IFN-γ production. The underlying mechanism is likely a donation of electrons by Fe2+ or oxidative stress. The…
View article: Polychlorinated biphenyls (PCBs) interact with drug metabolism in vivo
Polychlorinated biphenyls (PCBs) interact with drug metabolism in vivo Open
View article: ZIP10 as a potential therapeutic target in acute myeloid leukaemia
ZIP10 as a potential therapeutic target in acute myeloid leukaemia Open
Summary Acute myeloid leukaemia (AML) is a haematopoietic malignancy that continues to demonstrate lapses in current treatment modalities as evidenced by therapy refractory disease, disease relapse and high rates of lethality. The influenc…
View article: Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial
Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial Open
Purpose During hospitalization, circadian rhythms and sleep are often disrupted, which has negative effects on health outcomes. Therefore, we aimed to investigate whether a daylight intervention in the morning could improve the circadian r…
View article: Line-dropped gelatin multi-element calibration standards in LA-ICP-MS: a statistically verifying comparison with cryosectioned homogenized lung and liver as matrix-matched calibration standards and as corresponding reference materials
Line-dropped gelatin multi-element calibration standards in LA-ICP-MS: a statistically verifying comparison with cryosectioned homogenized lung and liver as matrix-matched calibration standards and as corresponding reference materials Open
Calibrations in LA-ICP-MS are typically very time-consuming and complex, as they need to be matched to the samples being measured and sectioned on a microtome. Alternatively, gelatin can be in droplet form or as a section, which is a more …
View article: Metabolic activation of WHO-congeners PCB28, 52, and 101 by human CYP2A6: evidence from in vitro and in vivo experiments
Metabolic activation of WHO-congeners PCB28, 52, and 101 by human CYP2A6: evidence from in vitro and in vivo experiments Open
Despite extensive research on the metabolism of polychlorinated biphenyls (PCBs), knowledge gaps persist regarding their isoform-specific biotransformation pathways. This study aimed to elucidate the role of different cytochrome P450 enzym…
View article: Ca2+ signals are essential for T-cell proliferation, while Zn2+ signals are necessary for T helper cell 1 differentiation
Ca2+ signals are essential for T-cell proliferation, while Zn2+ signals are necessary for T helper cell 1 differentiation Open
The regulation of T-cell fate is crucial for the balance between infection control and tolerance. Calcium (Ca 2+ ) and zinc (Zn 2+ ) signals are both induced after T-cell stimulation, but their specific roles in the fate of activation and …
View article: Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial
Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial Open
PURPOSE: During hospitalization, circadian rhythms and sleep are often disrupted, which has negative effects on health outcomes. Therefore, we aimed to investigate whether a daylight intervention in the morning could improve the circadian …
View article: Lead exposure by E-waste disposal and recycling in Agbogbloshie, Ghana
Lead exposure by E-waste disposal and recycling in Agbogbloshie, Ghana Open
Most of our volunteers had pathological BLL and CL. Preventive strategies are necessary to reduce health risks, particularly for vulnerable populations (i.e. children, pregnant women).
View article: Partial dechlorination of 2,4,4′-trichlorobiphenyl (PCB 28) mediated by recombinant human CYP1A2
Partial dechlorination of 2,4,4′-trichlorobiphenyl (PCB 28) mediated by recombinant human CYP1A2 Open
View article: Correspondence on “Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples”
Correspondence on “Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples” Open
ADVERTISEMENT RETURN TO ISSUEPREVCorrespondence/Rebut...Correspondence/RebuttalNEXTCorrespondence on "Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlorinated Biphenyls in Animal Samples"P.…
View article: Excretion kinetics of 1,3-dichlorobenzene and its urinary metabolites after controlled airborne exposure in human volunteers
Excretion kinetics of 1,3-dichlorobenzene and its urinary metabolites after controlled airborne exposure in human volunteers Open
The solvent 1,3-dichlorobenzene (1,3-DCB) is formed during thermal decomposition of the initiator 2,4-dichlorobenzoylperoxide in the production of silicone rubber with potential exposure of production workers as shown in previous works. De…
View article: Blood lead monitoring in a former mining area in Euskirchen, Germany: results of a representative random sample in 3- to 17-year-old children and minors
Blood lead monitoring in a former mining area in Euskirchen, Germany: results of a representative random sample in 3- to 17-year-old children and minors Open
View article: Blood Lead Monitoring in a Former Mining Area in Euskirchen, Germany—Volunteers across the Entire Population
Blood Lead Monitoring in a Former Mining Area in Euskirchen, Germany—Volunteers across the Entire Population Open
After centuries of mining in the district of Euskirchen, that is, in the communities of Mechernich and Kall, the lead concentration in the soil remains high, often exceeding regulatory guidelines. To clarify the lead body burden among resi…
View article: Predicting Hair Cortisol and Cortisone Concentration in Postpartum Women through Repeated Measurements of Perceived Stress
Predicting Hair Cortisol and Cortisone Concentration in Postpartum Women through Repeated Measurements of Perceived Stress Open
To investigate whether hair cortisol (HCC) and hair cortisone (HCNC) can be predicted by repeated stress reports from postpartum women in different mental health conditions (non-depressed, ND, adjustment disorder, AD, postpartum depression…
View article: New data on the metabolism of chloromethylisothiazolinone and methylisothiazolinone in human volunteers after oral dosage: excretion kinetics of a urinary mercapturic acid metabolite (“M-12”)
New data on the metabolism of chloromethylisothiazolinone and methylisothiazolinone in human volunteers after oral dosage: excretion kinetics of a urinary mercapturic acid metabolite (“M-12”) Open
View article: Metabolic activation and toxicological evaluation of polychlorinated biphenyls in Drosophila melanogaster
Metabolic activation and toxicological evaluation of polychlorinated biphenyls in Drosophila melanogaster Open
View article: The methylisothiazolinone and methylchloroisothiazolinone metabolite N-methylmalonamic acid (NMMA) in urine of children and adolescents in Germany – Human biomonitoring results of the German Environmental Survey 2014–2017 (GerES V)
The methylisothiazolinone and methylchloroisothiazolinone metabolite N-methylmalonamic acid (NMMA) in urine of children and adolescents in Germany – Human biomonitoring results of the German Environmental Survey 2014–2017 (GerES V) Open
View article: Depressive Symptoms After PCB Exposure: Hypotheses for Underlying Pathomechanisms via the Thyroid and Dopamine System
Depressive Symptoms After PCB Exposure: Hypotheses for Underlying Pathomechanisms via the Thyroid and Dopamine System Open
Polychlorinated biphenyls’ (PCB) exposure has been reported to be associated with depressive symptoms, which is correlated to lower dopamine- (DA) and thyroxine-concentrations (T4). T4 is necessary for DA-synthesis and it binds to transthy…