Paul Park
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View article: Spatial ecology and habitat selection of Eastern Pinesnakes: Case study on the importance of scale in conservation biology
Spatial ecology and habitat selection of Eastern Pinesnakes: Case study on the importance of scale in conservation biology Open
Species are in decline world-wide, driven by multiple factors including habitat fragmentation. Understanding the habitat selection processes of species in these fragmented landscapes has become a focus of ecological studies and is a major …
View article: Defining cervical spondylotic myelopathy surgical endotypes using comorbidity clustering: a Quality Outcomes Database cervical spondylotic myelopathy study
Defining cervical spondylotic myelopathy surgical endotypes using comorbidity clustering: a Quality Outcomes Database cervical spondylotic myelopathy study Open
OBJECTIVE Coexisting medical conditions are increasingly prevalent in surgical populations. The impact of multiple comorbidities on patient-reported outcomes (PROs) and endotypes of frequently co-occurring conditions for cervical spondylot…
View article: Validation of a novel artificial intelligence model (SpinePose) to automatically and accurately predict spinopelvic parameters using scoliosis radiographs in an external cohort
Validation of a novel artificial intelligence model (SpinePose) to automatically and accurately predict spinopelvic parameters using scoliosis radiographs in an external cohort Open
OBJECTIVE SpinePose was developed in 2024 as a novel artificial intelligence (AI) tool to automatically predict spinopelvic parameters with high accuracy and without the need for manual entry. The authors’ published results demonstrated ex…
View article: Editorial: Decoding cell fate: the critical roles of extracellular vesicles
Editorial: Decoding cell fate: the critical roles of extracellular vesicles Open
CITATION Chen Y, Ghavami S, Park PC and Irobi J (2025) Editorial: Decoding cell fate: the critical roles of extracellular vesicles.
View article: Auto-Rad: End-to-End Report Generation from Lumber Spine MRI Using Vision–Language Model
Auto-Rad: End-to-End Report Generation from Lumber Spine MRI Using Vision–Language Model Open
Background: Lumbar spinal stenosis (LSS) is a major cause of chronic lower back and leg pain, and is traditionally diagnosed through labor-intensive analysis of magnetic resonance imaging (MRI) scans by radiologists. This study aims to str…
View article: Loss of Negative Metabolic Feedback Drives <i>TET2</i> Mutant Inflammation
Loss of Negative Metabolic Feedback Drives <i>TET2</i> Mutant Inflammation Open
TET2 mutations are clinically significant mutations in clonal hematopoiesis of indeterminate potential (CHIP) and myeloid malignancies driving inflammation and clonal progression, but the underlying mechanism of how TET2 loss leads to thes…
View article: Editors’ Introduction: Rethinking the “One-Size-Fits-All” Approach in Spine Surgery
Editors’ Introduction: Rethinking the “One-Size-Fits-All” Approach in Spine Surgery Open
Although the "one-size-fits-all" mentality may enhance the standardization of different areas of medicine, this concept must be carefully reconsidered in the surgical treatment of spinal disease. The diversity of spinal pathologies, differ…
View article: Development and validation of an artificial intelligence model to accurately predict spinopelvic parameters
Development and validation of an artificial intelligence model to accurately predict spinopelvic parameters Open
OBJECTIVE Achieving appropriate spinopelvic alignment has been shown to be associated with improved clinical symptoms. However, measurement of spinopelvic radiographic parameters is time-intensive and interobserver reliability is a concern…
View article: 319 Development and Validation of an Artificial Intelligence Model to Accurately Predict Spinopelvic Parameters
319 Development and Validation of an Artificial Intelligence Model to Accurately Predict Spinopelvic Parameters Open
OBJECTIVES/GOALS: The correction of spinopelvic parameters is associated with better outcomes in patients with adult spinal deformity (ASD). This study presents a novel artificial intelligence (AI) tool that automatically predicts spinopel…
View article: Development and validation of an artificial intelligence model to accurately predict spinopelvic parameters
Development and validation of an artificial intelligence model to accurately predict spinopelvic parameters Open
Objective. Achieving appropriate spinopelvic alignment has been shown to be associated with improved clinical symptoms. However, measurement of spinopelvic radiographic parameters is time-intensive and interobserver reliability is a concer…
View article: An Integrated 3-Dimentional Navigation System Increases the Accuracy, Efficiency, and Safety of Percutaneous Thoracolumbar Pedicle Screw Placement in Minimally Invasive Approaches: A Randomized Cadaveric Study
An Integrated 3-Dimentional Navigation System Increases the Accuracy, Efficiency, and Safety of Percutaneous Thoracolumbar Pedicle Screw Placement in Minimally Invasive Approaches: A Randomized Cadaveric Study Open
Study Design Cadaveric study. Objectives The purpose of this study was to compare a novel, integrated 3D navigational system (NAV) and conventional fluoroscopy in the accuracy, efficiency, and radiation exposure of thoracolumbar percutaneo…
View article: Greater improvement in Neck Disability Index scores in women after surgery for cervical myelopathy: an analysis of the Quality Outcomes Database
Greater improvement in Neck Disability Index scores in women after surgery for cervical myelopathy: an analysis of the Quality Outcomes Database Open
OBJECTIVE There is a high prevalence of cervical myelopathy that requires surgery; as such, it is important to identify how different groups benefit from surgery. The American Association of Neurological Surgeons launched the Quality Outco…
View article: Future Role of Health Technology Assessment for Genomic Medicine in Oncology: A Canadian Laboratory Perspective
Future Role of Health Technology Assessment for Genomic Medicine in Oncology: A Canadian Laboratory Perspective Open
Genome-based testing in oncology is a rapidly expanding area of health care that is the basis of the emerging area of precision medicine. The efficient and considered adoption of novel genomic medicine testing is hampered in Canada by the …
View article: The Posterior Cranial Vertical Line: A Novel Radiographic Marker for Classifying Global Sagittal Alignment
The Posterior Cranial Vertical Line: A Novel Radiographic Marker for Classifying Global Sagittal Alignment Open
Objective: To define a novel radiographic measurement, the posterior cranial vertical line (PCVL), in an asymptomatic adult population to better understand global sagittal alignment.Methods: We performed a multicenter retrospective review …
View article: Three-level ACDF versus 3-level laminectomy and fusion: are there differences in outcomes? An analysis of the Quality Outcomes Database cervical spondylotic myelopathy cohort
Three-level ACDF versus 3-level laminectomy and fusion: are there differences in outcomes? An analysis of the Quality Outcomes Database cervical spondylotic myelopathy cohort Open
OBJECTIVE The authors sought to compare 3-level anterior with posterior fusion surgical procedures for the treatment of multilevel cervical spondylotic myelopathy (CSM). METHODS The authors analyzed prospective data from the 14 highest enr…
View article: Future role of Health Technology Assessment for Genomic Medicine in Oncology: A Canadian Laboratory Perspective
Future role of Health Technology Assessment for Genomic Medicine in Oncology: A Canadian Laboratory Perspective Open
Genome-based testing in oncology is a rapidly expanding area of health care which is the basis of the emerging area of precision medicine. Efficient and considered adoption of novel genomic medicine testing is hampered in Canada by the fra…
View article: Clinical characterization of the mutational landscape of 24,639 real-world samples from patients with myeloid malignancies
Clinical characterization of the mutational landscape of 24,639 real-world samples from patients with myeloid malignancies Open
Myeloid neoplasms represent a broad spectrum of hematological disorders for which somatic mutation status in key driver genes is important for diagnosis, prognosis and treatment. Here we summarize the findings of a targeted, next generatio…
View article: Robotic versus nonrobotic sacroiliac joint fusion
Robotic versus nonrobotic sacroiliac joint fusion Open
OBJECTIVE Robot-assisted pedicle screw placement in spinal fusion has been well studied. However, few studies have evaluated robot-assisted sacroiliac joint (SIJ) fusion. The aim of this study was to compare surgical characteristics, accur…
View article: Developing nonlinear k-nearest neighbors classification algorithms to identify patients at high risk of increased length of hospital stay following spine surgery
Developing nonlinear k-nearest neighbors classification algorithms to identify patients at high risk of increased length of hospital stay following spine surgery Open
OBJECTIVE Spondylolisthesis is a common operative disease in the United States, but robust predictive models for patient outcomes remain limited. The development of models that accurately predict postoperative outcomes would be useful to h…
View article: Which supervised machine learning algorithm can best predict achievement of minimum clinically important difference in neck pain after surgery in patients with cervical myelopathy? A QOD study
Which supervised machine learning algorithm can best predict achievement of minimum clinically important difference in neck pain after surgery in patients with cervical myelopathy? A QOD study Open
OBJECTIVE The purpose of this study was to evaluate the performance of different supervised machine learning algorithms to predict achievement of minimum clinically important difference (MCID) in neck pain after surgery in patients with ce…
View article: Defining postoperative C5 palsy and recovery: a systematic review
Defining postoperative C5 palsy and recovery: a systematic review Open
OBJECTIVE Postoperative C5 palsy (C5P) is a well-recognized and often-delayed complication of cervical spine surgery. Most patients recover within 6 months of onset, but the prognosis of severe cases is poor. The clinical significance and …
View article: Minimally invasive versus open transforaminal lumbar interbody fusion for grade I lumbar spondylolisthesis: 5-year follow-up from the prospective multicenter Quality Outcomes Database registry
Minimally invasive versus open transforaminal lumbar interbody fusion for grade I lumbar spondylolisthesis: 5-year follow-up from the prospective multicenter Quality Outcomes Database registry Open
OBJECTIVE Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) has been used to treat degenerative lumbar spondylolisthesis and is associated with expedited recovery, reduced operative blood loss, and shorter hospitalization…
View article: Anterior spinal hardware erosion of the pharyngoesophagus: A difficult reconstructive challenge—Our experience in nine patients
Anterior spinal hardware erosion of the pharyngoesophagus: A difficult reconstructive challenge—Our experience in nine patients Open
Key Points Pharyngoesophageal perforation secondary to anterior spinal hardware erosion is a difficult dilemma with many reconstructive options available. Multidisciplinary approach with thoracic surgery and neurosurgery is critical and ca…
View article: Navigated retrodiaphragmatic/retroperitoneal approach for the treatment of symptomatic kyphoscoliosis: an operative video
Navigated retrodiaphragmatic/retroperitoneal approach for the treatment of symptomatic kyphoscoliosis: an operative video Open
Retropleural, retrodiaphragmatic, and retroperitoneal approaches are utilized to access difficult thoracolumbar junction (T10–L2) pathology. The authors present a 58-year-old man with chronic low-back pain who failed years of conservative …