J. Pablo Arnoletti
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View article: Endoscopic or surgical gastroenterostomy for malignant gastric outlet obstruction: a randomised trial
Endoscopic or surgical gastroenterostomy for malignant gastric outlet obstruction: a randomised trial Open
Background Although surgical gastrojejunostomy (SGJ) is the standard method for palliation of gastric outlet obstruction (GOO), an endoscopic method—endoscopic ultrasound-guided gastroenterostomy (EUS-GE)—has been proposed as a novel, less…
View article: Supplementary Figure S4 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Figure S4 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Changes in tSMA and pSMA by clinicodemographic covariates bar charts.
View article: Supplementary Table S3 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Table S3 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Mean total skeletal muscle area (tSMA) and psoas skeletal muscle area (pSMA) at diagnosis and follow-up among PDAC cohort participants overall and according to edema status.
View article: Supplementary Table S2 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Table S2 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Select clinical and epidemiological characteristics of the study population of all PDAC patients in the FPC Cohort and according to those included versus excluded in the current analysis.
View article: Supplementary Figure S3 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Figure S3 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Directed acyclic graph for Cox proportional hazards regression. Directed acyclic graph representing all variables considered in building multivariable models for the Cox proportional hazards regression representing the associations of musc…
View article: Supplementary Figure S5 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Figure S5 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Forest plots of tSMA and pSMA changes and mortality.
View article: Data from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Data from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Background:Muscle loss influences pancreatic ductal adenocarcinoma (PDAC) outcomes, but treatment-related edema may cause overestimation of total skeletal muscle area (tSMA), confounding our understanding of muscle changes. However, no stu…
View article: Supplementary Table S5 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Table S5 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Adjusted mean change in total skeletal muscle area (tSMA) and psoas skeletal muscle area (pSMA) by clinically relevant covariables in subgroups by edema status.
View article: Supplementary Figure S1 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Figure S1 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Inclusion and exclusion criteria flow chart.
View article: Supplementary Figure S2 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Figure S2 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Directed acyclic graph for generalized linear model. Directed acyclic graph representing all variables considered in building multivariable models for the generalized linear models representing the associations of PDAC diagnosis with post-…
View article: Supplementary Figure S6 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Figure S6 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Sensitivity analysis changes in tSMA and pSMA bar charts.
View article: Supplementary Table S1 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
Supplementary Table S1 from The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma Open
Results of the change-in-estimate assessment of confounding.
View article: Race-based differences in serum biomarkers for cancer-associated cachexia in a diverse cohort of patients with pancreatic ductal adenocarcinoma
Race-based differences in serum biomarkers for cancer-associated cachexia in a diverse cohort of patients with pancreatic ductal adenocarcinoma Open
View article: Leveraging real-world data to predict cancer cachexia stage, quality of life, and survival in a racially and ethnically diverse multi-institutional cohort of treatment-naïve patients with pancreatic ductal adenocarcinoma
Leveraging real-world data to predict cancer cachexia stage, quality of life, and survival in a racially and ethnically diverse multi-institutional cohort of treatment-naïve patients with pancreatic ductal adenocarcinoma Open
Introduction Cancer-associated cachexia (CC) is a progressive syndrome characterized by unintentional weight loss, muscle atrophy, fatigue, and poor outcomes that affects most patients with pancreatic ductal adenocarcinoma (PDAC). The abil…
View article: EUS-guided gallbladder drainage in acute cholecystitis: long-term problems with surgical approach
EUS-guided gallbladder drainage in acute cholecystitis: long-term problems with surgical approach Open
View article: Data from Serum Biomarker Panels for the Detection of Pancreatic Cancer
Data from Serum Biomarker Panels for the Detection of Pancreatic Cancer Open
Purpose: Serum–biomarker based screening for pancreatic cancer could greatly improve survival in appropriately targeted high-risk populations.Experimental Design: Eighty-three circulating proteins were analyzed in sera of pat…
View article: CCR Translation for This Article from Serum Biomarker Panels for the Detection of Pancreatic Cancer
CCR Translation for This Article from Serum Biomarker Panels for the Detection of Pancreatic Cancer Open
CCR Translation for This Article from Serum Biomarker Panels for the Detection of Pancreatic Cancer
View article: Supplementary Data from Serum Biomarker Panels for the Detection of Pancreatic Cancer
Supplementary Data from Serum Biomarker Panels for the Detection of Pancreatic Cancer Open
Supplementary Figures S1-S2; Supplementary Tables S1-S2.
View article: Supplementary Data from Serum Biomarker Panels for the Detection of Pancreatic Cancer
Supplementary Data from Serum Biomarker Panels for the Detection of Pancreatic Cancer Open
Supplementary Figures S1-S2; Supplementary Tables S1-S2.
View article: CCR Translation for This Article from Serum Biomarker Panels for the Detection of Pancreatic Cancer
CCR Translation for This Article from Serum Biomarker Panels for the Detection of Pancreatic Cancer Open
CCR Translation for This Article from Serum Biomarker Panels for the Detection of Pancreatic Cancer
View article: Data from Serum Biomarker Panels for the Detection of Pancreatic Cancer
Data from Serum Biomarker Panels for the Detection of Pancreatic Cancer Open
Purpose: Serum–biomarker based screening for pancreatic cancer could greatly improve survival in appropriately targeted high-risk populations.Experimental Design: Eighty-three circulating proteins were analyzed in sera of pat…
View article: Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation
Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation Open
The portal venous circulation provides a conduit for pancreatic ductal adenocarcinoma (PDAC) tumor cells to the liver parenchyma sinusoids, a frequent site of metastasis. Turbulent flow in the portal circulation promotes retention of PDAC …
View article: Validation of the Orlando Protocol for endoscopic management of pancreatic fluid collections in the era of lumen‐apposing metal stents
Validation of the Orlando Protocol for endoscopic management of pancreatic fluid collections in the era of lumen‐apposing metal stents Open
Objectives Although lumen‐apposing metal stents (LAMS) are being increasingly used in lieu of plastic stents, the clinical approach to endoscopic management of pancreatic fluid collections (PFCs) is poorly standardized. We compared outcome…
View article: The Florida Pancreas Collaborative Next-Generation Biobank: Infrastructure to Reduce Disparities and Improve Survival for a Diverse Cohort of Patients with Pancreatic Cancer
The Florida Pancreas Collaborative Next-Generation Biobank: Infrastructure to Reduce Disparities and Improve Survival for a Diverse Cohort of Patients with Pancreatic Cancer Open
Background: Well-annotated, high-quality biorepositories provide a valuable platform to support translational research. However, most biorepositories have poor representation of minority groups, limiting the ability to address health dispa…
View article: The Florida Pancreas Collaborative Next-Generation Biobank: State-wide Infrastructure to Reduce Disparities and Improve Survival for a Racially and Ethnically Diverse Cohort of Patients with Pancreatic Cancer
The Florida Pancreas Collaborative Next-Generation Biobank: State-wide Infrastructure to Reduce Disparities and Improve Survival for a Racially and Ethnically Diverse Cohort of Patients with Pancreatic Cancer Open
Background Well-annotated, high-quality biorepositories provide a valuable platform to support translational research and discovery. However, most biorepositories have poor representation of minority groups, limiting the ability to address…
View article: Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells
Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells Open
View article: Issue Information
Issue Information Open
Clinical outcomes according to the
View article: Additional file 2 of Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells
Additional file 2 of Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells Open
Additional file 1: Figure S1. Oncogenic Akt1myr alone does not induce stromal changes and increased immune cell infiltration with cerulein injections. Table S1. Akt1Myr/KRasG12D mice with chronic inflammation progresses to more severe panc…
View article: External pancreatic stents after pancreaticoduodenectomy reduce pancreatic fistula rates and severity
External pancreatic stents after pancreaticoduodenectomy reduce pancreatic fistula rates and severity Open
View article: Perioperative infections after pancreaticoduodenectomy in patients with biliary stents
Perioperative infections after pancreaticoduodenectomy in patients with biliary stents Open