Joseph S. Ross
YOU?
Author Swipe
View article: Modeling In-Hospital Mortality Among Patients Undergoing Percutaneous Coronary Intervention with Acute Myocardial Infarction Complicated by Cardiogenic Shock Receiving Mechanical Circulatory Support
Modeling In-Hospital Mortality Among Patients Undergoing Percutaneous Coronary Intervention with Acute Myocardial Infarction Complicated by Cardiogenic Shock Receiving Mechanical Circulatory Support Open
Acute myocardial infarction complicated by cardiogenic shock (AMI-CS) is a heterogeneous clinical syndrome associated with substantial morbidity and mortality. We developed a machine learning-based mortality model to identify features and …
View article: Hospital Acquisition Costs for Breakthrough-Designated Devices Awarded Supplemental Medicare Reimbursement
Hospital Acquisition Costs for Breakthrough-Designated Devices Awarded Supplemental Medicare Reimbursement Open
This cross-sectional study compares manufacturer-reported and actual hospital acquisition costs for breakthrough-designated devices awarded supplemental Medicare reimbursement.
View article: Physician Composition of Hospitals’ Workforce And Mortality Across U.S. Hospitals
Physician Composition of Hospitals’ Workforce And Mortality Across U.S. Hospitals Open
Importance The clinical workforce composition in U.S. hospitals is shifting, with advanced practice practitioners (APPs) – nurse practitioners and physician assistants –assuming larger roles in inpatient care. How this mix relates to patie…
View article: Prescribing of GLP-1 Receptor Agonists for Adolescents with Obesity and Associated Disparities
Prescribing of GLP-1 Receptor Agonists for Adolescents with Obesity and Associated Disparities Open
This retrospective cohort study examined national prescribing patterns of glucagon like peptide 1 receptor agonists (GLP1RAs) for U.S. adolescents with obesity using electronic health record data from over 2 million patients aged 12 to 17 …
View article: Therapeutic benefit of the most expensive drugs covered by Medicare and Medicaid
Therapeutic benefit of the most expensive drugs covered by Medicare and Medicaid Open
Many of the most expensive drugs were rated as having low added clinical benefit. As the US begins price negotiations under the Inflation Reduction Act, understanding the clinical value of drugs may help inform debates over drug affordabil…
View article: Identifying common patterns in journals that retracted papers from paper mills: a cross-sectional study
Identifying common patterns in journals that retracted papers from paper mills: a cross-sectional study Open
This study suggests that paper mill retractions are concentrated in a small number of journals with common characteristics: high open access rates, intermediate impact factor quartiles, a high volume of citable items, and classification in…
View article: Determinants of clinical trial failure in multiple sclerosis: insights from ClinicalTrials.gov
Determinants of clinical trial failure in multiple sclerosis: insights from ClinicalTrials.gov Open
View article: Flexibility over rigor: stakeholder acceptance of the limitations of confirmatory studies following accelerated approval
Flexibility over rigor: stakeholder acceptance of the limitations of confirmatory studies following accelerated approval Open
Introduction Concerns about completing postmarketing requirements (PMRs) following accelerated approval (AA) of new drugs have been well documented. However, there has been little examination of specific barriers and facilitators to timely…
View article: Early Recalls and Clinical Validation Gaps in Artificial Intelligence–Enabled Medical Devices
Early Recalls and Clinical Validation Gaps in Artificial Intelligence–Enabled Medical Devices Open
This cross-sectional study examines whether lack of clinical validation and publicly traded manufacturer status were associated with recalls of artificial intelligence–enabled medical devices that had been cleared by the US Food and Drug A…
View article: National Patterns of Remote Patient Monitoring Service Availability at US Hospitals
National Patterns of Remote Patient Monitoring Service Availability at US Hospitals Open
BACKGROUND: Digital remote patient monitoring (RPM), such as home-based blood pressure, heart rate, or weight monitoring, enables longitudinal care outside traditional health care settings, especially in the vulnerable period after hospita…
View article: Industry payments to US neurologists related to multiple sclerosis drugs and prescribing (2015–2019): a retrospective cohort study
Industry payments to US neurologists related to multiple sclerosis drugs and prescribing (2015–2019): a retrospective cohort study Open
Objectives To measure the prevalence and magnitude of industry payments to neurologists prescribing multiple sclerosis (MS) drugs and determine whether payments are associated with prescribing. Design Retrospective observational study. Set…
View article: Confounder Selection in Observational Studies in High-Impact Medical and Epidemiological Journals
Confounder Selection in Observational Studies in High-Impact Medical and Epidemiological Journals Open
This cross-sectional study investigates whether there have been improvements over time in the methods reported for selecting confounders in observational studies published in the highest impact factor medical and epidemiological journals.
View article: Comparing Claims Data to Stroke and Bleeding in the NCDR Left Atrial Appendage Occlusion Registry
Comparing Claims Data to Stroke and Bleeding in the NCDR Left Atrial Appendage Occlusion Registry Open
In the LAAO Registry, International Classification of Diseases-Tenth Revision codes have moderate agreement with stroke, GIB, and intracranial hemorrhage, and overestimate most event rates compared to adjudicated registry-reported events. …
View article: Relationship between industry payments to physicians and prescription patterns for PCSK9is, ARNis and DOACs: A report from the NCDR PINNACLE registry
Relationship between industry payments to physicians and prescription patterns for PCSK9is, ARNis and DOACs: A report from the NCDR PINNACLE registry Open
Patients with ASCVD or HFrEF whose physicians received industry payments were more likely to be prescribed PCSK9 inhibitors or ARNi, regardless of the payment amount. For DOACs, an association with prescribing was observed only among physi…
View article: Heterogeneity of Cardiovascular Effects of Second‐Line Glucose‐Lowering Therapies in Adults With Type 2 Diabetes Across the Range of Moderate Baseline Cardiovascular Risk
Heterogeneity of Cardiovascular Effects of Second‐Line Glucose‐Lowering Therapies in Adults With Type 2 Diabetes Across the Range of Moderate Baseline Cardiovascular Risk Open
Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and sodium–glucose cotransporter‐2 inhibitors (SGLT2is) have favorable cardiovascular outcomes compared with dipeptidyl peptidase‐4 inhibitors (DPP4is) and sulfonylureas in ad…
View article: Regulatory Review Time of Vaccine Approvals in China Between 2005 and 2024
Regulatory Review Time of Vaccine Approvals in China Between 2005 and 2024 Open
This cross-sectional study examines the regulatory review times for vaccine product applications submitted through China’s National Medical Products Administration over the past 2 decades.
View article: Public Health Implications of Legal Challenges to the FDA’s Regulation of Laboratory-Developed Tests
Public Health Implications of Legal Challenges to the FDA’s Regulation of Laboratory-Developed Tests Open
Importance Laboratory-developed tests (LDTs) refer to in vitro diagnostics developed and used by individual laboratories. LDTs are widely used in modern medicine, with their results informing over 70% of clinical decisions. The US Food and…
View article: Representation of Women, Older Adults, and Racial and Ethnic Minoritized Patients in Pivotal Trials for US Food and Drug Administration Novel Oncology Therapeutic Approvals, 2012-2021: Bright Spot Trials and Trends Over Time
Representation of Women, Older Adults, and Racial and Ethnic Minoritized Patients in Pivotal Trials for US Food and Drug Administration Novel Oncology Therapeutic Approvals, 2012-2021: Bright Spot Trials and Trends Over Time Open
PURPOSE To examine trends over time in clinical trial diversity for oncology therapeutics, identify bright spot trials adequately representing Black or Latino patients, and examine their associations with trial characteristics. METHODS Thi…
View article: Access to Information Cited in National Organization for Rare Disorders Reports
Access to Information Cited in National Organization for Rare Disorders Reports Open
This cross-sectional study describes the availability and access cost to the public of research findings and other clinical insights relevant to rare diseases.
View article: Ransomware Attacks and Data Breaches in US Health Care Systems
Ransomware Attacks and Data Breaches in US Health Care Systems Open
This cross-sectional study analyzes ransomware attacks across all HIPAA-covered entities from 2010 to 2024 and examines their contribution to protected health information data breaches.
View article: Racial and Ethnic Reporting and Representation in Phase III Alzheimer’s Disease Clinical Trials in the US
Racial and Ethnic Reporting and Representation in Phase III Alzheimer’s Disease Clinical Trials in the US Open
Background Alzheimer’s disease (AD) disproportionately affects racial and ethnic minoritized populations in the United States, yet these groups remain markedly underrepresented in clinical research. Phase III clinical trials are critical f…
View article: Insulin rationing in states with and without insulin copay caps: a cross-sectional study
Insulin rationing in states with and without insulin copay caps: a cross-sectional study Open
View article: Nonconcurrent Control Use in FDA Approval of High-Risk Medical Devices
Nonconcurrent Control Use in FDA Approval of High-Risk Medical Devices Open
Importance The US Food and Drug Administration (FDA) may consider historical controls, objective performance criteria, or performance goals as alternatives to concurrent control groups in clinical studies evaluating safety and/or effective…
View article: Research Derived From Medicare’s Coverage With Evidence Development Program
Research Derived From Medicare’s Coverage With Evidence Development Program Open
This cross-sectional study assesses published research articles about medical items and services approved by the Coverage With Evidence Development program to characterize their scientific impact.
View article: Floods and cause-specific mortality in the United States applying a triply robust approach
Floods and cause-specific mortality in the United States applying a triply robust approach Open
View article: Differences In Debt Among Postgraduate Medical Residents By Self-Designated Race And Ethnicity, 2014–19
Differences In Debt Among Postgraduate Medical Residents By Self-Designated Race And Ethnicity, 2014–19 Open
The US physician workforce does not reflect the racial and ethnic makeup of the country's population, despite efforts to promote diversity. Becoming a physician requires significant time and financial investment, and populations that are u…
View article: Late adverse event reporting from medical device manufacturers to the US Food and Drug Administration: cross sectional study
Late adverse event reporting from medical device manufacturers to the US Food and Drug Administration: cross sectional study Open
Objective To describe the extent of late adverse event reporting by manufacturers to the US Food and Drug Administration’s (FDA) Manufacturer And User Facility Device Experience (MAUDE) database as well as the distribution of late reportin…
View article: Capacity assessment for EHR-based medical device post-market surveillance for synthetic mid-urethral slings among women with stress urinary incontinence: a NEST consortium study
Capacity assessment for EHR-based medical device post-market surveillance for synthetic mid-urethral slings among women with stress urinary incontinence: a NEST consortium study Open
Objectives To evaluate the feasibility for use of electronic health record (EHR) data in conducting adverse event surveillance among women who received mid-urethral slings (MUS) to treat stress urinary incontinence (SUI) in five health sys…
View article: Long-term drought and risk of infant mortality in Africa: A cross-sectional study
Long-term drought and risk of infant mortality in Africa: A cross-sectional study Open
Background As extreme events such as drought and flood are projected to increase in frequency and intensity under climate change, there is still large missing evidence on how drought exposure potentially impacts mortality among young child…
View article: Ten‐Year Medicare Use and Spending on the 10 Drugs Selected for Negotiation Under the Inflation Reduction Act
Ten‐Year Medicare Use and Spending on the 10 Drugs Selected for Negotiation Under the Inflation Reduction Act Open