A double network structure with metal ions was created to enhance the mechanical stability of the hydrogels and increase their low conductivity. For this purpose, the P(AM_AcOr_Gelatin) hydrogel was synthesized by combining gelatin, a biocompatible polymer, <i>N</i>-δ-acryloyl-ornithine (AcOr), an amino acid derivative, and acrylamide (AM). Because the amino acid-based monomer added charged groups to the hydrogel network, the hydrogel exhibited improved conductivity and motion sensitivity properties compared with …

A novel ion-pair receptor represents the first example of a small molecule capable of transporting highly polar zwitterions, including charged amino acids such as arginine and glutamate across lipid bilayers.

In this study, we present a thermoresponsive and electroactive hybrid microgel immobilized on an electrode surface, designed as a platform for electrochemically induced release of positively charged model substances. The microgel was synthesized using <i>N</i>-isopropylacrylamide (NIPA) copolymerized with sodium acrylate (AcNa) and cross-linked with a cystine derivative (BISS). Poly(3,4-ethylenedioxythiophene) (PEDOT) spheres were incorporated within the microgel matrix, enhancing its electroactive properties. The…

The aim of this work was the development of a novel stimuli-responsive hydrogel layer containing an acryloyl derivative of an α-amino acid and its electroanalytical characterization. The electroactive, electrosensitive, and thermosensitive gel layer was obtained through a two-step process. First, a hydrogel (p(NIPA-ArOr)) based on N-isopropylacrylamide (NIPA) and an acryloyl derivative of ornithine (ArOr) were synthesized and electrodeposited using electrochemically induced free-radical polymerization. Cyclic volt…

Studies at three-phase electrodes (TPE, glassy carbon electrode, an aqueous and organic solution) are often performed to detect organic and inorganic anions. However, it is difficult to find a redox probe or ionophore that would allow the transfer of highly hydrophilic sulphate ions. Recently, TPE studies of ion pair receptors consisting of a crown ether cation-binding site and a squaramide anion-binding domain have emerged, offering the ability to extract extremely hydrophilic sulphate salts. In this article, we …