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View article: Effects of resistance exercise training on oxygen consumption and minute by minute efficiency during the six-minute walk test in female breast cancer survivors
Effects of resistance exercise training on oxygen consumption and minute by minute efficiency during the six-minute walk test in female breast cancer survivors Open
Objective To determine the effects of resistance exercise training (RET) on oxygen consumption and minute-by-minute efficiency during the Six-Minute Walk Test (6MWT) in healthy postmenopausal female breast cancer survivors. Methods Eleven …
View article: “If I am here, it is because the system failed”: a critical qualitative study of global commercial clinical trials for advanced cancer in Chile
“If I am here, it is because the system failed”: a critical qualitative study of global commercial clinical trials for advanced cancer in Chile Open
The conditions that make Chile an attractive hub for cancer commercial clinical trials are determined by an interplay of global, national, and community-level structural arrangements between public and private actors. Chile serves as an im…
View article: Previous infection with HAdV-D36 is associated with lower bone density and increased osteoporosis risk at the femoral neck in postmenopausal women
Previous infection with HAdV-D36 is associated with lower bone density and increased osteoporosis risk at the femoral neck in postmenopausal women Open
View article: Resistance exercise training similarly improves work efficiency and measured submaximal oxygen consumption during the 6-min walk test in healthy postmenopausal women and breast cancer survivors
Resistance exercise training similarly improves work efficiency and measured submaximal oxygen consumption during the 6-min walk test in healthy postmenopausal women and breast cancer survivors Open
NCT05690295.
View article: Return to work in head and neck cancer survivors: an exploratory multimethod study at a cancer centre in Santiago, Chile
Return to work in head and neck cancer survivors: an exploratory multimethod study at a cancer centre in Santiago, Chile Open
Being a woman was associated with less RTW. Future interventions should provide support in reintegration into the workplace. This study constitutes the first published data on RTW in Chilean patients.
View article: Skeletal muscle mass, strength, and physical performance gains are similar between healthy postmenopausal women and postmenopausal breast cancer survivors after 12 weeks of resistance exercise training
Skeletal muscle mass, strength, and physical performance gains are similar between healthy postmenopausal women and postmenopausal breast cancer survivors after 12 weeks of resistance exercise training Open
Twelve weeks of RET significantly increases skeletal muscle mass, strength, and physical performance in postmenopausal women. No differences were observed between healthy postmenopausal women and postmenopausal breast cancer survivors. The…
View article: Shaping Clinical Policy for Salvage Radiotherapy After Radical Prostatectomy in Prostate Cancer: Bridging the Gap Between Clinical Trials and Daily Practice
Shaping Clinical Policy for Salvage Radiotherapy After Radical Prostatectomy in Prostate Cancer: Bridging the Gap Between Clinical Trials and Daily Practice Open
Purpose and Objective Salvage radiotherapy (sRT) can have similar outcomes to adjuvant radiotherapy (aRT) if administered at the earliest evidence of biochemical recurrence. RADICALS‐RT was the first trial to support this hypothesis and a …
View article: Influence of Seropositivity against Adenovirus-36 on the Risk of Obesity and Insulin Resistance in the Child Population of Southern Chile
Influence of Seropositivity against Adenovirus-36 on the Risk of Obesity and Insulin Resistance in the Child Population of Southern Chile Open
Background: Previous infection with Adenovirus-36 (HAdv-D36) has been associated with adipogenesis and glycemic regulation in cell culture and animal models. In humans, HAdv-D36 antibodies correlate with increased obesity risk yet paradoxi…
View article: Skeletal Muscle Mass, Strength, and Physical Performance Gains Are Similar Between Healthy Postmenopausal Women and Postmenopausal Breast Cancer Survivors After 12 Weeks of Resistance Exercise Training
Skeletal Muscle Mass, Strength, and Physical Performance Gains Are Similar Between Healthy Postmenopausal Women and Postmenopausal Breast Cancer Survivors After 12 Weeks of Resistance Exercise Training Open
Background : Resistance exercise training (RET) has been shown to be effective in increasing skeletal muscle mass and strength in healthy postmenopausal women. In postmenopausal breast cancer survivors, however, the effects of RET on these…
View article: Estado nutricional preoperatorio y complicaciones en cirugía digestiva oncológica: un estudio retrospectivo en un centro de cáncer chileno
Estado nutricional preoperatorio y complicaciones en cirugía digestiva oncológica: un estudio retrospectivo en un centro de cáncer chileno Open
Introducción: La desnutrición es una condición frecuente en pacientes oncológicos y puede estar presente en un 40-80% de éstos. En cirugía gastrointestinal, es ampliamente conocida la relación entre la desnutrición preoperatoria y las comp…
View article: Adenovirus 36 seropositivity influences the expression of anti-adipogenic lncRNAs GAS5 and MEG3 in adipose tissue obtained from subjects with obesity
Adenovirus 36 seropositivity influences the expression of anti-adipogenic lncRNAs GAS5 and MEG3 in adipose tissue obtained from subjects with obesity Open
Background Adenovirus 36 (Ad-36) promotes adipogenesis and the development of human obesity. Induction of PPARγ by Ad-36 seems to have a central role in maintenance of adipogenic status. There is limited information about epigenetic mechan…
View article: Muscle Mass and Strength Gains Following Resistance Exercise Training in Older Adults 65–75 Years and Older Adults Above 85 Years
Muscle Mass and Strength Gains Following Resistance Exercise Training in Older Adults 65–75 Years and Older Adults Above 85 Years Open
Resistance exercise training (RET) can be applied effectively to increase muscle mass and function in older adults (65–75 years). However, it has been speculated that older adults above 85 years are less responsive to the benefits of RET. …
View article: Effects of high-intensity interval training on lean mass, strength, and power of the lower limbs in healthy old and young people
Effects of high-intensity interval training on lean mass, strength, and power of the lower limbs in healthy old and young people Open
Introduction: Whether high-intensity interval training (HIIT) can improve lean mass, strength, and power of the lower limbs in young and older people is still under discussion. This study aimed to determine the effect of HIIT on lean mass,…
View article: High-intensity interval training reduces the induction of neutrophil extracellular traps in older men using live-neutrophil imaging as biosensor
High-intensity interval training reduces the induction of neutrophil extracellular traps in older men using live-neutrophil imaging as biosensor Open
Neutrophil extracellular trap formation (NETosis) is a mechanism used by neutrophils to capture pathogens with their own DNA. However, the exacerbation of this immune response is related to serious inflammatory diseases. Aging is known to …
View article: Distribución geográfica de la incidencia de cáncer de beneficiarios de un convenio de atención oncológica en Chile
Distribución geográfica de la incidencia de cáncer de beneficiarios de un convenio de atención oncológica en Chile Open
View article: Clinical and histopathological features of follicular thyroid cancer in Chile
Clinical and histopathological features of follicular thyroid cancer in Chile Open
At diagnosis, most FTCs were nodules of low or intermediate suspicion at ultrasound, nearly two thirds had indeterminate cytology according to the Bethesda system, and nearly 50% of them were of low risk of recurrence.
View article: The Armed Conflict and the Impact on Patients With Cancer in Ukraine: Urgent Considerations
The Armed Conflict and the Impact on Patients With Cancer in Ukraine: Urgent Considerations Open
On February 24, 2022, a war began within the Ukrainian borders. At least 3.0 million Ukrainian inhabitants have already fled the country. Critical infrastructure, including hospitals, has been damaged. Children with cancer were urgently tr…
View article: Anthropometric Parameters, Lower Limb Functionality and Quality of Life After High-Intensity Interval Training in Healthy Young People Versus Older Adults
Anthropometric Parameters, Lower Limb Functionality and Quality of Life After High-Intensity Interval Training in Healthy Young People Versus Older Adults Open
The aim of this study was to determine the effects of High-intensity interval training (HIIT) on the quality of life in healthy young people (YNG) and older adults (OLD)and its correlation with physical health status (anthropometric parame…
View article: Pre-existing conditions in Latin America and factors associated with adverse outcomes of COVID-19: A review
Pre-existing conditions in Latin America and factors associated with adverse outcomes of COVID-19: A review Open
The coronavirus disease 2019 (COVID-19) pandemic, produced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly throughout the world. Latin American and the Caribbean countries have been harshly affected by t…
View article: Convalescent Plasma in COVID-19. Mortality-Safety First Results of the Prospective Multicenter FALP 001-2020 Trial
Convalescent Plasma in COVID-19. Mortality-Safety First Results of the Prospective Multicenter FALP 001-2020 Trial Open
Background The use of convalescent plasma (CP) to treat COVID-19 has shown promising results; however, its effectiveness remains uncertain. The purpose of this study was to determine the safety and mortality of CP among patients hospitaliz…
View article: Alta prevalencia de dislipidemias y riesgo aterogénico en una población infanto-juvenil
Alta prevalencia de dislipidemias y riesgo aterogénico en una población infanto-juvenil Open
There is a high prevalence of dyslipidemia in the studied population, which is associated with an increased cardiometabolic risk. The indices of atherogenicity and particularly AIP are correlated with nutritional status, abdominal obesity …
View article: Rol de la cirugía bariátrica/metabólica en el manejo de la diabetes mellitus 2. Consenso SOCHED/SCCBM
Rol de la cirugía bariátrica/metabólica en el manejo de la diabetes mellitus 2. Consenso SOCHED/SCCBM Open
Diabetes Mellitus (DM) and obesity are a public health problem in Chile. Bariatric surgery is the most effective treatment alternative to achieve a significant and sustained weight reduction in patients with morbid obesity. The results of …
View article: Estrés psicológico y síndrome metabólico
Estrés psicológico y síndrome metabólico Open
Chronic psychological stress is longitudinally associated with the MetS score. Further, psychological stress and depressive symptoms at baseline predicted elevated MetS score trajectories, and a highest waist circumference.
View article: Alta prevalencia de trastornos nutricionales por exceso, resistencia insulínica y síndrome metabólico en escolares de la comuna de Carahue, Región de la Araucanía
Alta prevalencia de trastornos nutricionales por exceso, resistencia insulínica y síndrome metabólico en escolares de la comuna de Carahue, Región de la Araucanía Open
There was a high prevalence of overweight, obesity and MetS in these participants. Our results suggest that the IR criteria according to Barja allows to identify cases with higher metabolic risk.
View article: Análisis crítico del tratamiento de la enfermedad hepática grasa no alcohólica
Análisis crítico del tratamiento de la enfermedad hepática grasa no alcohólica Open
Non-alcoholic fatty liver disease (NAFDL) includes fatty liver or simple steatosis, characterized by lipid deposits in hepatocytes and more advanced stages such as steatohepatitis (NASH) and non-alcoholic cirrhosis. Physical inactivity, hy…
View article: II Consenso de la Sociedad Chilena de Endocrinología y Diabetes sobre resistencia a la insulina
II Consenso de la Sociedad Chilena de Endocrinología y Diabetes sobre resistencia a la insulina Open
Insulin resistance is a prevalent condition commonly associated with unhealthy lifestyles. It affects several metabolic pathways, increasing risk of abnormalities at different organ levels. Thus, diverse medical specialties should be invol…