Juan Sieira
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View article: Phrenic nerve palsy during cryoballoon ablation of atrial fibrillation: a minor complication or a wolf in sheep's clothing? Insights on late arrhythmia recurrences from a propensity score-matched analysis
Phrenic nerve palsy during cryoballoon ablation of atrial fibrillation: a minor complication or a wolf in sheep's clothing? Insights on late arrhythmia recurrences from a propensity score-matched analysis Open
Background Pulmonary vein isolation (PVI) has become the cornerstone of percutaneous atrial fibrillation (AF) treatment, and cryoballoon ablation (CB-A) has been shown to be non-inferior to radiofrequency (RF) ablation in terms of safety a…
View article: Genetic variants associated with ventricular arrhythmias during ajmaline test in Brugada syndrome
Genetic variants associated with ventricular arrhythmias during ajmaline test in Brugada syndrome Open
Graphical AbstractPathogenic/Likely Pathogenic variants identified in SCN5A and associated with ajmaline-induced ventricular fibrillation following ACMG guidelines
View article: Assessment of activation delay in the right ventricular outflow tract as a potential complementary diagnostic tool for Brugada Syndrome
Assessment of activation delay in the right ventricular outflow tract as a potential complementary diagnostic tool for Brugada Syndrome Open
Aims In patients with Brugada syndrome (BrS), diagnosis relies primarily on the presence of the characteristic type 1 electrocardiographic (ECG) pattern. The aim of this study was to propose an alternative diagnostic method in situations w…
View article: Pulsed field ablation in the elderly via a pentaspline multielectrode catheter: safety, efficacy, and comparison with cryoballoon devices
Pulsed field ablation in the elderly via a pentaspline multielectrode catheter: safety, efficacy, and comparison with cryoballoon devices Open
Background Catheter ablation is an effective treatment for atrial fibrillation (AF). Pulsed field ablation (PFA) has emerged as a novel energy modality, which relies on high-voltage electric fields to achieve cardiac tissue ablation. Data …
View article: Cardiac sympathetic denervation in patients with refractory ventricular arrhythmias: a single-center experience
Cardiac sympathetic denervation in patients with refractory ventricular arrhythmias: a single-center experience Open
Background Cardiac sympathetic denervation (CSD) is a therapeutic option in patients with refractory ventricular arrhythmias (VAs). However, prospective data on long term outcomes in different population cohorts undergoing CSD are scarce. …
View article: Genetic variants associated with ventricular arrhythmias during ajmaline test in Brugada syndrome
Genetic variants associated with ventricular arrhythmias during ajmaline test in Brugada syndrome Open
Background Ventricular arrhythmias (VA) occur in approximately 2-18% of patients with Brugada syndrome (BrS) undergoing sodium channel blockers (SCBs) testing. While these arrhythmias have been linked to the SCN5A gene, the impact of speci…
View article: In-vivo endocardial and epicardial mapping of human sinus node: from electrical landmarks to anatomical landmarks
In-vivo endocardial and epicardial mapping of human sinus node: from electrical landmarks to anatomical landmarks Open
Background The human sinoatrial node (SAN) pacemaker is a complex structure located at the right atrium-superior vena cava (SVC) junction. It is intramural with a depth of 1 to 3 mm, and is composed of anastomosing clusters of specialized …
View article: Grid annotation vs. ablation tags in predicting lesion area coverage for pulmonary vein isolation using a variable-loop circular catheter
Grid annotation vs. ablation tags in predicting lesion area coverage for pulmonary vein isolation using a variable-loop circular catheter Open
Background The Variable-Loop Circular Catheter (VLCC) is a bidirectional multi-electrode catheter capable of electroanatomical mapping and pulsed field energy delivery for the treatment of atrial fibrillation (AF). Objective to compare Gri…
View article: Cryoballoon Ablation With the POLARx FIT or the Arctic Front Advance Pro for Paroxysmal Atrial Fibrillation: A Health Economic Analysis
Cryoballoon Ablation With the POLARx FIT or the Arctic Front Advance Pro for Paroxysmal Atrial Fibrillation: A Health Economic Analysis Open
Background Pulmonary vein isolation (PVI) is the main ablation strategy for the treatment of paroxysmal atrial fibrillation. Different technologies are available for PVI, including various cryoballoon catheters (CB-A). Compared with the Ar…
View article: Pulmonary vein isolation durability with fluoroscopy or 3D mapping-guided radiofrequency balloon ablation: a mandated remap study
Pulmonary vein isolation durability with fluoroscopy or 3D mapping-guided radiofrequency balloon ablation: a mandated remap study Open
Background Effective balloon positionnking during pulmonary vein isolation (PVI) with a radiofrequency balloon (RFB) is crucial for optimal energy delivery, maximising lesion formation, and preventing gaps. Traditionally, fluoroscopy is us…
View article: A Hybrid Minimally Invasive Atrial Fibrillation Ablation Procedure Using Unilateral Thoracoscopy and Endocardial Pulsed Field Ablation: An Early Feasibility Study
A Hybrid Minimally Invasive Atrial Fibrillation Ablation Procedure Using Unilateral Thoracoscopy and Endocardial Pulsed Field Ablation: An Early Feasibility Study Open
(1) Objective: To examine the efficiency and efficacy of using endovascular mapping and pulsed field ablation in the setting of a hybrid video-assisted thoracoscopic atrial fibrillation (AF) ablation procedure. (2) Methods: Eleven consecut…
View article: 2D speckle-tracking echocardiography assessment of left atrial and left ventricular mechanics: outcomes in patients with atrial fibrillation treated with hybrid ablation and left atrial appendage surgical closure
2D speckle-tracking echocardiography assessment of left atrial and left ventricular mechanics: outcomes in patients with atrial fibrillation treated with hybrid ablation and left atrial appendage surgical closure Open
Background and aims Hybrid atrial fibrillation (AF) ablation is a therapeutic option in non-paroxysmal AF. Our study examines cardiac mechanics changes after hybrid AF ablation plus epicardial closure of left atrial appendage (LAA). Method…
View article: Electroanatomic mapping reconstruction with photogrammetry across different mapping systems
Electroanatomic mapping reconstruction with photogrammetry across different mapping systems Open
Background Automatic digital photogrammetry produces digital reproductions of objects using photographs. The aim of this study is to analyze feasibility of photogrammetry for electroanatomic map (EAM) reconstruction from different mapping …
View article: Long-term clinical outcomes of asymptomatic patients with spontaneous type 1 Brugada electrocardiographic pattern undergoing electrophysiologic study for risk stratification
Long-term clinical outcomes of asymptomatic patients with spontaneous type 1 Brugada electrocardiographic pattern undergoing electrophysiologic study for risk stratification Open
View article: Cryoballoon Ablation With the POLARx FIT or the Arctic Front Advance Pro for Paroxysmal Atrial Fibrillation: A Health Economic Analysis
Cryoballoon Ablation With the POLARx FIT or the Arctic Front Advance Pro for Paroxysmal Atrial Fibrillation: A Health Economic Analysis Open
Background: Pulmonary vein isolation (PVI) is the main ablation strategy for the treatment of paroxysmal atrial fibrillation. Different technologies are available for PVI, including various cryoballoon catheters (CB-A). Compared with the A…
View article: Noninvasive electrocardiographic imaging assessment of conduction system pacing: A novel algorithm to assess intraventricular synchrony
Noninvasive electrocardiographic imaging assessment of conduction system pacing: A novel algorithm to assess intraventricular synchrony Open
View article: Spontaneous type 1 ECG and arrhythmic risk in Brugada syndrome: A meta-analysis of adjusted time-to-event data
Spontaneous type 1 ECG and arrhythmic risk in Brugada syndrome: A meta-analysis of adjusted time-to-event data Open
View article: Multielectrode catheter-based pulsed electric field vs. cryoballoon for atrial fibrillation ablation: a systematic review and meta-analysis
Multielectrode catheter-based pulsed electric field vs. cryoballoon for atrial fibrillation ablation: a systematic review and meta-analysis Open
Aims Pulsed field ablation (PFA) is an innovative technology recently adopted for the treatment of atrial fibrillation (AF). Preclinical and clinical studies have reported a remarkable safety profile, as a result of its tissue-specific eff…
View article: Multielectrode catheter-based pulsed field ablation of persistent and long-standing persistent atrial fibrillation
Multielectrode catheter-based pulsed field ablation of persistent and long-standing persistent atrial fibrillation Open
Aims Rhythm control of non-paroxysmal atrial fibrillation (AF) is significantly more challenging, as a result of arrhythmia perpetuation promoting atrial substrate changes and AF maintenance. We describe a tailored ablation strategy target…
View article: Focal Pulsed Field Ablation for Premature Ventricular Contractions: A Multicenter Experience
Focal Pulsed Field Ablation for Premature Ventricular Contractions: A Multicenter Experience Open
BACKGROUND: Pulsed field ablation (PFA) is a novel technology for catheter-based atrial arrhythmia treatment. Evidence of its application for ventricular arrhythmia ablation is still limited. In this study, we describe the feasibility and …
View article: Noninvasive electrocardiographic imaging assessment of intraventricular synchrony for conduction system pacing device: a novel algorythm to assess intraventricular synchrony
Noninvasive electrocardiographic imaging assessment of intraventricular synchrony for conduction system pacing device: a novel algorythm to assess intraventricular synchrony Open
Structured Abstract Background Left Bundle branch area pacing has become the procedure of choice for various indications including atrioventricular block and considered to be a physiologic modality of pacing compared to RV apex pacing. Obj…
View article: Predicting and Recognizing Drug‐Induced Type I Brugada Pattern Using ECG‐Based Deep Learning
Predicting and Recognizing Drug‐Induced Type I Brugada Pattern Using ECG‐Based Deep Learning Open
Background Brugada syndrome (BrS) has been associated with sudden cardiac death in otherwise healthy subjects, and drug‐induced BrS accounts for 55% to 70% of all patients with BrS. This study aims to develop a deep convolutional neural ne…
View article: PO-01-131 FIRST EXPERIENCE OF FOCAL PULSED FIELD ABLATION FOR PREMATURE VENTRICULAR CONTRACTIONS
PO-01-131 FIRST EXPERIENCE OF FOCAL PULSED FIELD ABLATION FOR PREMATURE VENTRICULAR CONTRACTIONS Open
View article: A propensity score matched comparison of pulsed field versus hybrid ablation in patients with long standing persistent atrial fibrillation
A propensity score matched comparison of pulsed field versus hybrid ablation in patients with long standing persistent atrial fibrillation Open
Introduction On one hand pulsed-field ablation (PFA) has shown favourable data in terms of safety and efficiency for pulmonary veins isolation (PVI). One the other hand, hybrid ablation results in better outcomes in patients with persisten…
View article: Comparative analysis of pulsed-field and cryoballoon ablation in octogenarians with atrial fibrillation: a multicenter study
Comparative analysis of pulsed-field and cryoballoon ablation in octogenarians with atrial fibrillation: a multicenter study Open
Background The prevalence of atrial fibrillation (AF) increases with advancing age, and AF contributes to higher rates of stroke, dementia, heart failure, and mortality. Catheter ablation is recognized as an effective treatment for AF; how…
View article: In-vivo mapping of human polymorphic ventricular tachycardia in Brugada syndrome
In-vivo mapping of human polymorphic ventricular tachycardia in Brugada syndrome Open
Background/introduction Brugada syndrome (BrS) is associated with ventricular fibrillation (VF) and polymorphic ventricular tachycardia (PMVT). Different mechanisms have been described for human PMVT, including epicardial drifting of rotat…
View article: Pericarditis prophylactic therapy after sinus node–sparing hybrid ablation for inappropriate sinus tachycardia/postural orthostatic sinus tachycardia
Pericarditis prophylactic therapy after sinus node–sparing hybrid ablation for inappropriate sinus tachycardia/postural orthostatic sinus tachycardia Open
View article: Redo procedures after sinus node sparing hybrid ablation for inappropriate sinus tachycardia/postural orthostatic sinus tachycardia
Redo procedures after sinus node sparing hybrid ablation for inappropriate sinus tachycardia/postural orthostatic sinus tachycardia Open
Aims A novel sinus node (SN) sparing hybrid ablation for inappropriate sinus node tachycardia (IST)/postural orthostatic tachycardia syndrome (POTS) has been demonstrated to be an effective and safe therapeutic option in patients with symp…
View article: Pulsed electric field, cryoballoon, and radiofrequency for paroxysmal atrial fibrillation ablation: a propensity score-matched comparison
Pulsed electric field, cryoballoon, and radiofrequency for paroxysmal atrial fibrillation ablation: a propensity score-matched comparison Open
Aims Pulsed field ablation (PFA) has emerged as a novel, non-thermal energy source to selectively ablate cardiac tissue. We describe a multicentre experience on pulmonary vein isolation (PVI) via the pentaspline Farapulse™ PFA system vs. t…
View article: Coronary artery disease in atrial fibrillation ablation: impact on arrhythmic outcomes
Coronary artery disease in atrial fibrillation ablation: impact on arrhythmic outcomes Open
Aims Catheter ablation (CA) is an established treatment for atrial fibrillation (AF). A computed tomography (CT) may be performed before ablation to evaluate the anatomy of pulmonary veins. The aim of this study is to investigate the preva…