R. Steele
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View article: Variation in fecal hemoglobin concentrations: Cross-sectional analysis of a screening trial and a screening program in Sweden
Variation in fecal hemoglobin concentrations: Cross-sectional analysis of a screening trial and a screening program in Sweden Open
Objectives To assess variation in fecal hemoglobin concentration according to year and season of fecal immunochemical test screening in Sweden, the detection rate of advanced neoplasia, and factors that could influence fecal immunochemical…
View article: A Provincial Interoperability Journey to Streamline Resident Transitions and Improve Integrated Care between Hospital & Long-Term Care
A Provincial Interoperability Journey to Streamline Resident Transitions and Improve Integrated Care between Hospital & Long-Term Care Open
Background: Healthcare systems across Ontario, Canada operate using health record systems with varying data structures, code sets, and interoperability capabilities, resulting in predominantly paper-based transfer of information. For patie…
View article: Large-Scale Multi-omic Biosequence Transformers for Modeling Protein-Nucleic Acid Interactions.
Large-Scale Multi-omic Biosequence Transformers for Modeling Protein-Nucleic Acid Interactions. Open
The transformer architecture has revolutionized bioinformatics and driven progress in the understanding and prediction of the properties of biomolecules. To date, most biosequence transformers have been trained on single-omic data-either p…
View article: Behavioural interventions to increase uptake of FIT colorectal screening in Scotland (TEMPO): a nationwide, eight-arm, factorial, randomised controlled trial
Behavioural interventions to increase uptake of FIT colorectal screening in Scotland (TEMPO): a nationwide, eight-arm, factorial, randomised controlled trial Open
View article: Preferences for treatment outcomes in rectal cancer: A discrete choice experiment among patients and healthy volunteers
Preferences for treatment outcomes in rectal cancer: A discrete choice experiment among patients and healthy volunteers Open
Aim Treatment for rectal cancer can leave patients with a permanent stoma or bowel dysfunction. In this work we aimed to examine preferences for treatment outcomes among people with and without rectal cancer. Method Our discrete choice exp…
View article: Colonoscopy findings after increasing two‐stool faecal immunochemical test (FIT) cut‐off: Cross‐sectional analysis of the SCREESCO randomized trial
Colonoscopy findings after increasing two‐stool faecal immunochemical test (FIT) cut‐off: Cross‐sectional analysis of the SCREESCO randomized trial Open
Background We determined the impact of an increased two‐stool faecal immunochemical test (FIT) cut‐off on colonoscopy positivity and relative sensitivity and specificity in the randomized controlled screening trial screening of Swedish col…
View article: Considerations for using potential surrogate endpoints in cancer screening trials
Considerations for using potential surrogate endpoints in cancer screening trials Open
View article: Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews
Probability of major depression diagnostic classification using semi-structured versus fully structured diagnostic interviews Open
Background: Different diagnostic interviews are used as reference standards for major depression classification in research. Semi-structured interviews involve clinical judgement, whereas fully structured interviews are completely scripted…
View article: Meteoritical Society
Meteoritical Society Open
UK), for the presentation "Fe-sulfides in experimentally and naturally
View article: The role of endoscopist adenoma detection rate in in sex differences in colonoscopy findings: cross-sectional analysis of the SCREESCO randomized controlled trial
The role of endoscopist adenoma detection rate in in sex differences in colonoscopy findings: cross-sectional analysis of the SCREESCO randomized controlled trial Open
This study provides no evidence that endoscopist skill measured by ADR underlies the sex difference in adenoma detection at colonoscopy. This study has trial number NCT02078804 and is registered with ClinicalTrials.gov.
View article: DATA FUSION: A PROJECT UPDATE & PATHWAY FORWARD
DATA FUSION: A PROJECT UPDATE & PATHWAY FORWARD Open
View article: Interval cancers in a national colorectal screening programme based on faecal immunochemical testing: Implications for faecal haemoglobin concentration threshold and sex inequality
Interval cancers in a national colorectal screening programme based on faecal immunochemical testing: Implications for faecal haemoglobin concentration threshold and sex inequality Open
Objective To compare interval cancer proportions (ICP) in the faecal immunochemical test (FIT)-based Scottish Bowel Screening Programme (SBoSP) with the former guaiac faecal occult blood test (gFOBT)-based SBoSP and investigate association…
View article: An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles
An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles Open
Objective New screening tests for colorectal cancer (CRC) are rapidly emerging. Conducting trials with mortality reduction as the end point supporting their adoption is challenging. We re-examined the principles underlying evaluation of ne…
View article: POS1232 EFFECT MODIFICATION OF CANCER ON THE ASSOCIATION BETWEEN DYSPHAGIA AND MORTALITY IN EARLY IDIOPATHIC INFLAMMATORY MYOPATHIES
POS1232 EFFECT MODIFICATION OF CANCER ON THE ASSOCIATION BETWEEN DYSPHAGIA AND MORTALITY IN EARLY IDIOPATHIC INFLAMMATORY MYOPATHIES Open
View article: Improved use of faecal immunochemical tests for haemoglobin in the Scottish bowel screening programme
Improved use of faecal immunochemical tests for haemoglobin in the Scottish bowel screening programme Open
Objectives This study aimed to develop a risk-scoring model in the Scottish Bowel Screening Programme incorporating faecal haemoglobin concentration with other risk factors for colorectal cancer. Methods Data were collected for all individ…
View article: Increasing uptake of FIT colorectal screening: protocol for the TEMPO randomised controlled trial testing a suggested deadline and a planning tool
Increasing uptake of FIT colorectal screening: protocol for the TEMPO randomised controlled trial testing a suggested deadline and a planning tool Open
Introduction Screening can reduce deaths from colorectal cancer (CRC). Despite high levels of public enthusiasm, participation rates in population CRC screening programmes internationally remain persistently below target levels. Simple beh…
View article: Sex variation in colorectal cancer mortality: trends and implications for screening
Sex variation in colorectal cancer mortality: trends and implications for screening Open
Background Colorectal cancer (CRC) screening using faecal tests reduces disease-specific mortality. To investigate mortality and its association with sex, rates in women and men, and in different age ranges, were examined, before and after…
View article: Faecal haemoglobin concentration predicts all-cause mortality
Faecal haemoglobin concentration predicts all-cause mortality Open
View article: Faecal haemoglobin concentrations are associated with all-cause mortality and cause of death in colorectal cancer screening
Faecal haemoglobin concentrations are associated with all-cause mortality and cause of death in colorectal cancer screening Open
Background Colorectal cancer (CRC) screening reduces all-cause and CRC-related mortality. New research demonstrates that the faecal haemoglobin concentration (f-Hb) may indicate the presence of other serious diseases not related to CRC. We…
View article: The role of endoscopist adenoma detection rate in in sex differences in colonoscopy findings: cross-sectional analysis of the SCREESCO randomized controlled trial
The role of endoscopist adenoma detection rate in in sex differences in colonoscopy findings: cross-sectional analysis of the SCREESCO randomized controlled trial Open
Fewer adenomas are detected at colonoscopy in women compared to men and failure to detect adenomas and sessile serrated polyps is associated with an increased risk of post-colonoscopy colorectal cancer. The aim of this study was to investi…
View article: Introduction to the Minitrack on Innovative Applications of Technologies in University - Industry Collaboration to Prepare for the Future of Work
Introduction to the Minitrack on Innovative Applications of Technologies in University - Industry Collaboration to Prepare for the Future of Work Open
View article: Understanding patient barriers and facilitators to uptake of lung screening using low dose computed tomography: a mixed methods scoping review of the current literature
Understanding patient barriers and facilitators to uptake of lung screening using low dose computed tomography: a mixed methods scoping review of the current literature Open
View article: An evaluation of the feasibility of implementing the BeWEL lifestyle intervention programme for people at increased risk of colorectal cancer – from research to real life
An evaluation of the feasibility of implementing the BeWEL lifestyle intervention programme for people at increased risk of colorectal cancer – from research to real life Open
Background The BeWEL randomised controlled trial (RCT) of weight loss in people with colorectal adenomas demonstrated that a significant proportion of people are interested in lifestyle interventions (49%) and clinically relevant changes i…
View article: Optimizing the implementation of lung cancer screening in Scotland: Focus group participant perspectives in the LUNGSCOT study
Optimizing the implementation of lung cancer screening in Scotland: Focus group participant perspectives in the LUNGSCOT study Open
Introduction Targeted lung cancer screening is effective in reducing lung cancer and all‐cause mortality according to major trials in the United Kingdom and Europe. However, the best ways of implementing screening in local communities requ…
View article: Clinical and functional outcomes of reverse total shoulder arthroplasty supplemented with latissimus dorsi transfer: a systematic review and meta-analysis
Clinical and functional outcomes of reverse total shoulder arthroplasty supplemented with latissimus dorsi transfer: a systematic review and meta-analysis Open
View article: What are common barriers and helpful solutions to colorectal cancer screening? A cross-sectional survey to develop intervention content for a planning support tool
What are common barriers and helpful solutions to colorectal cancer screening? A cross-sectional survey to develop intervention content for a planning support tool Open
Objective Colorectal screening using faecal immunochemical tests (FITs) can save lives if the people invited participate. In Scotland, most people intend to complete a FIT but this is not reflected in uptake rates. Planning interventions c…
View article: Do faecal test-based colorectal cancer screening pilots provide data that are reflected in subsequent programmes? Evidence from interval cancer proportions
Do faecal test-based colorectal cancer screening pilots provide data that are reflected in subsequent programmes? Evidence from interval cancer proportions Open
Objective Guidelines on colorectal cancer (CRC) screening with guaiac faecal occult blood tests (gFOBTs) and faecal immunochemical tests (FITs) include the need for a pilot before a programme is introduced. Interval cancers (ICs), cancers …
View article: What can We Learn From High-Performing Screening Programs to Increase Bowel Cancer Screening Participation in Australia?
What can We Learn From High-Performing Screening Programs to Increase Bowel Cancer Screening Participation in Australia? Open
Background Colorectal cancer (CRC) is the second most diagnosed cancer in men and women and second most common cause of cancer death in Australia; Australia’s CRC incidence and mortality are among the world’s highest. The Australian Nation…
View article: Identification and Quantification of Carbon Phases in Conversion Fuel for the Transient Reactor Test Facility
Identification and Quantification of Carbon Phases in Conversion Fuel for the Transient Reactor Test Facility Open
As part of an overall effort to convert US research reactors to low-enriched uranium (LEU) fuel use, a LEU conversion fuel is being designed for the Transient Reactor Test Facility (TREAT) at the Idaho National Laboratory. TREAT fuel compa…
View article: Strategies to minimise the current disadvantages experienced by women in faecal immunochemical test-based colorectal cancer screening
Strategies to minimise the current disadvantages experienced by women in faecal immunochemical test-based colorectal cancer screening Open
Currently, women are disadvantaged compared to men in colorectal cancer (CRC) screening, particularly in programmes that use faecal immunochemical tests for haemoglobin (FIT) followed by colonoscopy. Although there is no single cause for a…