Subhash Chander
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View article: Acute kidney injury induced by topical hair straightening products: A systematic review
Acute kidney injury induced by topical hair straightening products: A systematic review Open
BACKGROUND Hair straightening products containing formaldehyde, glycolic acid, and glyoxylic acid may be nephrotoxic, as several studies have reported acute kidney injury (AKI) induced by these chemicals. AIM To investigate the clinical fe…
View article: NAMS task force report on oral cancer
NAMS task force report on oral cancer Open
EXECUTIVE SUMMARY Oral cancer is the term described as cancers occurring in the mouthparts that include lips, cheeks, sinuses, tongue, hard and soft palate, or the base of the mouth extending up to the oropharynx. Globally, oral cancer ran…
View article: Type of arrhythmias and the risk of sudden cardiac death in dialysis patients: a systematic review and meta-analysis
Type of arrhythmias and the risk of sudden cardiac death in dialysis patients: a systematic review and meta-analysis Open
Background Patients on long-term dialysis for end-stage kidney disease have a high mortality rate, predominantly due to sudden cardiac death (SCD), which is associated with an increased risk of arrhythmias compared to the general populatio…
View article: Effect of low vs. high vancomycin trough level on the clinical outcomes of adult patients with sepsis or gram-positive bacterial infections: a systematic review and meta-analysis
Effect of low vs. high vancomycin trough level on the clinical outcomes of adult patients with sepsis or gram-positive bacterial infections: a systematic review and meta-analysis Open
Background & objective The Infectious Disease Society of America guidelines recommend vancomycin trough levels of 15–20 mg/L for severe methicillin-resistant Staphylococcus aureus. However, recent consensus guidelines of four infectious di…
View article: Antiarrhythmic drug therapy and catheter ablation in patients with paroxysmal or persistent atrial fibrillation: a systematic review and meta-analysis
Antiarrhythmic drug therapy and catheter ablation in patients with paroxysmal or persistent atrial fibrillation: a systematic review and meta-analysis Open
Background Catheter ablation and antiarrhythmic drug therapy are utilized for rhythm control in atrial fibrillation (AF), but their comparative effectiveness, especially with contemporary treatment modalities, remains undefined. We conduct…
View article: Evaluating the efficacy of different volume resuscitation strategies in acute pancreatitis patients: a systematic review and meta-analysis
Evaluating the efficacy of different volume resuscitation strategies in acute pancreatitis patients: a systematic review and meta-analysis Open
Introduction Acute pancreatitis poses a significant health risk due to the potential for pancreatic necrosis and multi-organ failure. Fluid resuscitation has demonstrated positive effects; however, consensus on the ideal intravenous fluid …
View article: Closing the gender gap in the authorship of hematology/oncology-related randomized controlled trials requires inclusive effort from male and female senior researchers
Closing the gender gap in the authorship of hematology/oncology-related randomized controlled trials requires inclusive effort from male and female senior researchers Open
Importance : Severe gender gap in academic research output is pervasive across all medical specialties, including hematology and oncology. Objective : This bibliometric study aimed to investigate the representation of females in premier fi…
View article: A Systematic Review of the Attitude, Beliefs, and Acceptance of COVID-19 Vaccine in the Western and Eastern Hemisphere
A Systematic Review of the Attitude, Beliefs, and Acceptance of COVID-19 Vaccine in the Western and Eastern Hemisphere Open
Background The availability of an effective vaccine does not equate to its use; its effectiveness primarily depends on vaccine acceptance by the targeted population. Despite the rapid development and widespread access to the COVID-19 vacci…
View article: Changing Faces of Authorship: A Study of Gender, Race, Regional Disparities in Gastroenterology/Hepatology-related RCTs. A Two Decade Analysis (2000-2022)
Changing Faces of Authorship: A Study of Gender, Race, Regional Disparities in Gastroenterology/Hepatology-related RCTs. A Two Decade Analysis (2000-2022) Open
Objective To investigate gender, racial, ethnic, and regional disparities in first and senior authorship positions in gastroenterology/hepatology-related randomised controlled trials (RCT). Design Retrospective bibliometric analysis of Pub…
View article: Glycemic Control in Critically Ill COVID-19 Patients: Systematic Review and Meta-Analysis
Glycemic Control in Critically Ill COVID-19 Patients: Systematic Review and Meta-Analysis Open
Background: Given the mortality risk in COVID-19 patients, it is necessary to estimate the impact of glycemic control on mortality rates among inpatients by designing and implementing evidence-based blood glucose (BG) control methods. Ther…
View article: Improving Healthcare Quality by Unifying the American Electronic Medical Record Systems. Time for Change
Improving Healthcare Quality by Unifying the American Electronic Medical Record Systems. Time for Change Open
Innovation development in healthcare has paved the path towards the improvement in system efficiency, patient care and cost-effective healthcare services, increasing the overall efficiency of the healthcare system in a significant manner. …
View article: Types of Arrhythmias and the risk of sudden cardiac death in dialysis patients: A Systematic Review and Meta-analysis
Types of Arrhythmias and the risk of sudden cardiac death in dialysis patients: A Systematic Review and Meta-analysis Open
Background Patients on long-term dialysis therapy due to ESRD tend to have a high mortality rate, predominantly due to cardiovascular complications, which is associated with an increased risk of arrhythmias compared to the general populati…
View article: Mortality and Mode of Dialysis
Mortality and Mode of Dialysis Open
Background Dialysis is an intervention used chiefly to cover poorly functioning kidneys’ ultrafiltration and diffusion functions. Dialysis can be performed using three major approaches: peritoneal dialysis, hemodialysis, and continuous ren…
View article: Design, synthesis, anti-acetylcholinesterase evaluation and molecular modelling studies of novel coumarin-chalcone hybrids
Design, synthesis, anti-acetylcholinesterase evaluation and molecular modelling studies of novel coumarin-chalcone hybrids Open
The major enzyme responsible for the hydrolytic breakdown of the neurotransmitter acetylcholine (ACh) is acetylcholinesterase (AChE). Acetylcholinesterase inhibitors (AChEIs) are the most prescribed class of medications for the treatment o…
View article: Discovery of multitargeting inhibitors for the treatment of COVID-19: An in- silico studies
Discovery of multitargeting inhibitors for the treatment of COVID-19: An in- silico studies Open
Coronavirus disease-2019 (COVID-19), a global pandemic has currently infected more than 247 million people around the world. Nowadays, several receptors of COVID-19 have been reported, and few of them are explored for drug discovery. New m…
View article: Effect of COVID-19 pandemic on education and psychology of medical students in Himachal Pradesh (India)
Effect of COVID-19 pandemic on education and psychology of medical students in Himachal Pradesh (India) Open
Background: WHO announced COVID-19 which is caused by SARS-CoV-2 as pandemic on 11 March 2020. In India first case of COVID-19 registered in Kerala on 29 January 2020 after that cases started to increase gradually. Government of India anno…
View article: Antenatal care providers’ attitudes and beliefs towards maternal vaccination in Kenya
Antenatal care providers’ attitudes and beliefs towards maternal vaccination in Kenya Open
Background: Maternal immunization is known to be one of the best strategies to protect both mothers and their infants from infectious diseases. Studies have shown that healthcare providers play a critical role in implementation of maternal…