Tian Gao
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View article: Qingyu formula inhibits ferroptosis in HK-2 cells and in a diabetic nephropathy mouse model via the Nrf2/SLC7A11/GPX4 pathway
Qingyu formula inhibits ferroptosis in HK-2 cells and in a diabetic nephropathy mouse model via the Nrf2/SLC7A11/GPX4 pathway Open
View article: Spatial distribution and pedigree age of traditional handicraft intangible cultural heritage in the Yellow River Basin
Spatial distribution and pedigree age of traditional handicraft intangible cultural heritage in the Yellow River Basin Open
View article: Marsupenaeus japonicus HSP90’s Function Under Low Temperature Stress
Marsupenaeus japonicus HSP90’s Function Under Low Temperature Stress Open
Molecular chaperones, especially heat shock proteins (HSPs) have vital functions in cells’ responses to stress. Here, we cloned and sequenced the complete complementary DNA encoding HSP90 (MjHSP90) from the shrimp Marsupenaeus japonicus. T…
View article: Cloning of Heat Shock Protein 90 from the Marsupenaeus Japonicus and its Anti-Apoptotic Role in Low Temperature Stress
Cloning of Heat Shock Protein 90 from the Marsupenaeus Japonicus and its Anti-Apoptotic Role in Low Temperature Stress Open
View article: Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying MicroRNA-29a Improves Ovarian Function of Mice with Primary Ovarian Insufficiency by Targeting HMG-Box Transcription Factor/Wnt/β-Catenin Signaling
Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying MicroRNA-29a Improves Ovarian Function of Mice with Primary Ovarian Insufficiency by Targeting HMG-Box Transcription Factor/Wnt/β-Catenin Signaling Open
Background. Primary ovarian insufficiency (POI) is a female disease characterized by ovarian function loss under 40 years old. Transplantation of exosomes is an encouraging regenerative medicine method that has the potential for restoring …
View article: Four-octyl itaconate improves osteoarthritis by enhancing autophagy in chondrocytes via PI3K/AKT/mTOR signalling pathway inhibition
Four-octyl itaconate improves osteoarthritis by enhancing autophagy in chondrocytes via PI3K/AKT/mTOR signalling pathway inhibition Open
Osteoarthritis (OA) is a highly prevalent and chronic disorder that is associated with a substantial social and economic burden. Itaconate, as an important regulator of cellular inflammation, is a metabolite synthesised by an enzyme encode…
View article: Protein kinases regulate hyperactivated motility of human sperm
Protein kinases regulate hyperactivated motility of human sperm Open
Once the sperm enters into the female reproductive tract, they undergo an important process called capacitation, which involves a series of physiological and biochemical changes that ensure fertilization. During capacitation, calcium ions …
View article: <i>AKAP1</i> Deficiency Attenuates Diet‐Induced Obesity and Insulin Resistance by Promoting Fatty Acid Oxidation and Thermogenesis in Brown Adipocytes
<i>AKAP1</i> Deficiency Attenuates Diet‐Induced Obesity and Insulin Resistance by Promoting Fatty Acid Oxidation and Thermogenesis in Brown Adipocytes Open
Altering the balance between energy intake and expenditure is a major strategy for treating obesity. Nonetheless, despite the progression in antiobesity drugs on appetite suppression, therapies aimed at increasing energy expenditure are li…
View article: Periprosthetic metastasis following total hip arthroplasty in a patient with lung carcinoma
Periprosthetic metastasis following total hip arthroplasty in a patient with lung carcinoma Open
Rationale: Periprosthetic osteolysis secondary to septic loosening and aseptic loosening is a well-described phenomenon associated with artificial hip arthroplasty. Periprosthetic bone loss as a result of metastatic infiltration is an unco…
View article: PKCζ Phosphorylates SIRT6 to Mediate Fatty Acid β-Oxidation in Colon Cancer Cells
PKCζ Phosphorylates SIRT6 to Mediate Fatty Acid β-Oxidation in Colon Cancer Cells Open
View article: p53 cooperates with SIRT6 to regulate cardiolipin de novo biosynthesis
p53 cooperates with SIRT6 to regulate cardiolipin de novo biosynthesis Open
View article: 797 Aberrant SIRT6 expression contributes to melanoma growth: Role of autophagy paradox and IGF-Akt signaling
797 Aberrant SIRT6 expression contributes to melanoma growth: Role of autophagy paradox and IGF-Akt signaling Open
View article: Sirtuins in glucose and lipid metabolism
Sirtuins in glucose and lipid metabolism Open
Sirtuins are evolutionarily conserved protein, serving as nicotinamide adenine dinucleotide-dependent deacetylases or adenosine diphosphate-ribosyltransferases. The mammalian sirtuins family, including SIRT1~7, is involved in many biologic…