Donald J. Tindall
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View article: Supplementary Figure 3 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 3 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 79K, Mass spectrometric analysis of SENL fractions 2, 3, and 4 obtained from HPLC. The total ion chromatogram retention time and the mass spectrum of individual peaks for the fractions 2, 3, and 4 are depicted in the panel A to C, re…
View article: Supplementary Figure 7 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 7 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 103K, Molecular structures for the compounds shown in the mass spectrum are depicted.
View article: Supplementary Figure 1 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 1 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 113K, Fractionation of SENL was performed using a Kinetex C18 column on a Shimadzu HPLC system. The experiments were performed in triplicate; a representative HPLC chromatogram of SENL is shown.
View article: Data from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Data from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
Azadirachta indica, commonly known as neem, has gained worldwide prominence because of its medical properties, namely antitumor, antiviral, anti-inflammatory, antihyperglycemic, antifungal, and antibacterial activities. Despite these promi…
View article: Supplementary Figure 8 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 8 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 89K, HPLC and Mass spectrometric analysis of mice plasma and tumor tissues for the bioavailability of SENL compounds after oral administration of SENL, 200 mg/kg body weight. A, HPLC chromatogram of plasma of mice treated with SENL. …
View article: Supplementary Figure Legends from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure Legends from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 71K, Legends to Supplementary Figures 1 through 8.
View article: Supplementary Figure 7 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 7 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 103K, Molecular structures for the compounds shown in the mass spectrum are depicted.
View article: Supplementary Figure 2 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 2 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 185K, The peaks labeled in the HPLC chromatogram were evaluated for cytotoxic activity against PC3 cells. The fractions collected from HPLC were concentrated using SpeedVac at 4 degrees C, and equal weights of the fractions were reco…
View article: Supplementary Figure 2 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 2 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 185K, The peaks labeled in the HPLC chromatogram were evaluated for cytotoxic activity against PC3 cells. The fractions collected from HPLC were concentrated using SpeedVac at 4 degrees C, and equal weights of the fractions were reco…
View article: Supplementary Figure 6 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 6 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 46K, Mass spectrometric analysis of SENL fraction 14 obtained from HPLC and the standards nimbolide and 2′, 3′-dehydrosalannol. The total ion chromatogram retention time and the mass spectrum of individual peaks are depicted in the p…
View article: Supplementary Figure 8 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 8 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 89K, HPLC and Mass spectrometric analysis of mice plasma and tumor tissues for the bioavailability of SENL compounds after oral administration of SENL, 200 mg/kg body weight. A, HPLC chromatogram of plasma of mice treated with SENL. …
View article: Supplementary Figure 3 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 3 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 79K, Mass spectrometric analysis of SENL fractions 2, 3, and 4 obtained from HPLC. The total ion chromatogram retention time and the mass spectrum of individual peaks for the fractions 2, 3, and 4 are depicted in the panel A to C, re…
View article: Supplementary Figure 4 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 4 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 69K, Mass spectrometric analysis of SENL fractions 5, 6, and 7 obtained from HPLC. The total ion chromatogram retention time and the mass spectrum of individual peaks for the fractions 5, 6, and 7 are depicted in the panel A to C, re…
View article: Supplementary Figure 5 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 5 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 64K, Mass spectrometric analysis of SENL fractions 9, 11, and 12 obtained from HPLC. The total ion chromatogram retention time and the mass spectrum of individual peaks for the fractions 9, 11, and 12 are depicted in the panel A to C…
View article: Supplementary Figure 6 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 6 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 46K, Mass spectrometric analysis of SENL fraction 14 obtained from HPLC and the standards nimbolide and 2′, 3′-dehydrosalannol. The total ion chromatogram retention time and the mass spectrum of individual peaks are depicted in the p…
View article: Supplementary Figure 4 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 4 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 69K, Mass spectrometric analysis of SENL fractions 5, 6, and 7 obtained from HPLC. The total ion chromatogram retention time and the mass spectrum of individual peaks for the fractions 5, 6, and 7 are depicted in the panel A to C, re…
View article: Supplementary Figure 5 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 5 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 64K, Mass spectrometric analysis of SENL fractions 9, 11, and 12 obtained from HPLC. The total ion chromatogram retention time and the mass spectrum of individual peaks for the fractions 9, 11, and 12 are depicted in the panel A to C…
View article: Supplementary Figure 1 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure 1 from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 113K, Fractionation of SENL was performed using a Kinetex C18 column on a Shimadzu HPLC system. The experiments were performed in triplicate; a representative HPLC chromatogram of SENL is shown.
View article: Data from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Data from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
Azadirachta indica, commonly known as neem, has gained worldwide prominence because of its medical properties, namely antitumor, antiviral, anti-inflammatory, antihyperglycemic, antifungal, and antibacterial activities. Despite these promi…
View article: Supplementary Figure Legends from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth
Supplementary Figure Legends from Preclinical Evaluation of the Supercritical Extract of <i>Azadirachta Indica</i> (Neem) Leaves <i>In Vitro</i> and <i>In Vivo</i> on Inhibition of Prostate Cancer Tumor Growth Open
PDF - 71K, Legends to Supplementary Figures 1 through 8.
View article: Supplementary Table 4B from Global Methylation Profiling for Risk Prediction of Prostate Cancer
Supplementary Table 4B from Global Methylation Profiling for Risk Prediction of Prostate Cancer Open
PDF file - 273K, Significance of methylation in prostate cancer tissue samples from 4 microarrays with the batch effect
View article: Supplementary Table 4D from Global Methylation Profiling for Risk Prediction of Prostate Cancer
Supplementary Table 4D from Global Methylation Profiling for Risk Prediction of Prostate Cancer Open
PDF file - 267K, Significance of methylation in prostate cancer tissue samples from 4 microarrays with the batch effect
View article: Supplementary Table 2 from Global Methylation Profiling for Risk Prediction of Prostate Cancer
Supplementary Table 2 from Global Methylation Profiling for Risk Prediction of Prostate Cancer Open
XLS file - 34K, Most significantly methylated genes associated with prostate cancer recurrence from the Cox univariate analysis
Supplementary Table 1A from Global Methylation Profiling for Risk Prediction of Prostate Cancer Open
PDF file - 419K, Significantly methylated genes in prostate cancer tissues from the binary group comparisons
Supplementary Table 4C from Global Methylation Profiling for Risk Prediction of Prostate Cancer Open
PDF file - 111K, Significance of methylation in prostate cancer tissue samples from 4 microarrays with the batch effect
Data from Global Methylation Profiling for Risk Prediction of Prostate Cancer Open
Purpose: The aim of this study was to investigate the promoter hypermethylation as diagnostic markers to detect malignant prostate cells and as prognostic markers to predict the clinical recurrence of prostate cancer.Experimental Design: D…
Data from Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation Open
Clinical trials have established the benefit of androgen deprivation therapy (ADT) combined with radiotherapy in prostate cancer. ADT sensitizes prostate cancer to radiotherapy-induced death at least in part through inhibition of DNA repai…
Supplementary Table 2 from Global Methylation Profiling for Risk Prediction of Prostate Cancer Open
XLS file - 34K, Most significantly methylated genes associated with prostate cancer recurrence from the Cox univariate analysis
Data from Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation Open
Clinical trials have established the benefit of androgen deprivation therapy (ADT) combined with radiotherapy in prostate cancer. ADT sensitizes prostate cancer to radiotherapy-induced death at least in part through inhibition of DNA repai…
Supplementary Table 4B from Global Methylation Profiling for Risk Prediction of Prostate Cancer Open
PDF file - 273K, Significance of methylation in prostate cancer tissue samples from 4 microarrays with the batch effect