Jacques Van Dam
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View article: Novel mouse model reveals neurodevelopmental origin of PMM2-CDG brain pathology
Novel mouse model reveals neurodevelopmental origin of PMM2-CDG brain pathology Open
Congenital disorders of glycosylation (CDG) are a group of neurogenetic conditions resulting from disruptions in the cellular glycosylation machinery. The majority of CDG patients have compound heterozygous pathogenic variants in the phosp…
View article: An oral robotic pill reliably and safely delivers teriparatide with high bioavailability in healthy volunteers: A phase 1 study
An oral robotic pill reliably and safely delivers teriparatide with high bioavailability in healthy volunteers: A phase 1 study Open
Aims The incidence of osteoporosis is projected to exceed 70 million people over the age of 65 years by 2030. Osteoanabolic agents, such as teriparatide and abaloparatide, are not only effective in reducing fracture incidence but also impr…
View article: Preference for a Novel Oral Alternative to Parenterally Administered Medications
Preference for a Novel Oral Alternative to Parenterally Administered Medications Open
Patients taking injections and prescribing physicians strongly prefer oral dosing to parenteral administration of biologics even if dosing frequency with the oral option, such as the RP, is increased.
View article: SAT235 An Orally Administered Robotic Pill (RP) Reliably And Safely Delivers the Human Parathyroid Hormone Analog hPTH(1-34) (Teriparatide) With High Bioavailability in Healthy Human Volunteers: A Phase 1 Study
SAT235 An Orally Administered Robotic Pill (RP) Reliably And Safely Delivers the Human Parathyroid Hormone Analog hPTH(1-34) (Teriparatide) With High Bioavailability in Healthy Human Volunteers: A Phase 1 Study Open
Disclosure: J.T. Myers: Employee; Self; Rani Therapeutics. Stock Owner; Self; Rani Therapeutics. A. Dasari: Employee; Self; Rani Therapeutics. Stock Owner; Self; Rani Therapeutics. A. Battiwala: Employee; Self; Rani Therapeutics. Stock Own…
View article: Infliximab Redosing During Massive GI Bleeding Resulting from Severe Crohn’s Disease
Infliximab Redosing During Massive GI Bleeding Resulting from Severe Crohn’s Disease Open
In moderate-to-severe Crohn’s disease (CD), early introduction of biologics is indicated. However, a standard frequency induction regimen may be insufficient for disease activity control in patients with significant ongoing hematochezia. W…
View article: Transenteric delivery of antibodies via an orally ingestible robotic pill yields high bioavailability comparable to parenteral administration in awake canines
Transenteric delivery of antibodies via an orally ingestible robotic pill yields high bioavailability comparable to parenteral administration in awake canines Open
Biotherapeutics such as peptides and antibodies are highly efficacious clinically but, unlike conventional medications, cannot be administered orally as they get digested and inactivated. Thus, biotherapeutics require parenteral routes for…
View article: Tu1047 THE EFFECT OF MONTH OF FELLOW TRAINING ON FLUOROSCOPY TIME, CONTRAST DOSE AND TOTAL ENDOSCOPY TIME
Tu1047 THE EFFECT OF MONTH OF FELLOW TRAINING ON FLUOROSCOPY TIME, CONTRAST DOSE AND TOTAL ENDOSCOPY TIME Open
View article: 254 – Validation of Blue Light Imaging (BLI) Criteria for the Optical Characterization of Colorectal Polyps by the U.S. Bli Working Group
254 – Validation of Blue Light Imaging (BLI) Criteria for the Optical Characterization of Colorectal Polyps by the U.S. Bli Working Group Open
View article: DDW 2019: Activities and Interests of the AGA Council
DDW 2019: Activities and Interests of the AGA Council Open
View article: Spectroscopy for Esophageal Diseases.
Spectroscopy for Esophageal Diseases. Open
View article: DDW 2017: Activities and Interests of the AGA Council
DDW 2017: Activities and Interests of the AGA Council Open
Disease Week® (DDW) just around the corner, we have compiled the following section highlights and meeting guides prepared by the AGA Council Sections listed below.We hope that this feature helps support the basic and translational research…
View article: The feasibility of R0 resection of locally advanced pancreatic cancer involving major visceral arteries (T4 lesions) using arterial resections and reconstructions: short- and long-term outcomes
The feasibility of R0 resection of locally advanced pancreatic cancer involving major visceral arteries (T4 lesions) using arterial resections and reconstructions: short- and long-term outcomes Open